scholarly journals RNA methylation in vaccinia virus-infected chick embryo fibroblasts treated with homologous interferon

1978 ◽  
Vol 5 (7) ◽  
pp. 2441-2454 ◽  
Author(s):  
Hans Kroath ◽  
Hans J. Gross ◽  
Christoph Jungwirth ◽  
Gerhard Bodo
Keyword(s):  
Chick Embryo ◽  
Vaccinia Virus ◽  
Rna Methylation ◽  
Embryo Fibroblasts

scholarly journals Mushrooms as a source of substances with antiviral activity

2014 ◽  
Vol 16 (2) ◽  
pp. 215-220 ◽  
Author(s):  
Martyna Kandefer-Szerszeń ◽  
Zbigniew Kawecki ◽  
Bogusław Sałata ◽  
Maria Witek
Keyword(s):  
Tissue Culture ◽  
Chick Embryo ◽  
Antiviral Activity ◽  
Vaccinia Virus ◽  
Fungal Species ◽  
Water Extracts ◽  
Boletus Edulis ◽  
Vaccinia Viruses ◽  
Embryo Fibroblasts ◽  
Armillariella Mellea

Water extracts the fructifications of 56 species of fungi were examined as a source of antiviral substances with activity against VS and vaccinia viruses. Extracts from 16 fungal species exhibited the antiviral activity. Water extracts from <i>Boletus edulis</i> active against vaccinia virus and extract from <i>Armillariella mellea</i> active against VS virus are particularly worth nothing. Both of them in applied concentrations were not toxic in chick embryo fibroblasts tissue culture.

scholarly journals INHIBITION OF RELEASE OF VACCINIA VIRUS BY N1-ISONICOTINOYL-N2-3-METHYL-4-CHLOROBENZOYLHYDRAZINE

1969 ◽  
Vol 129 (4) ◽  
pp. 795-808 ◽  
Author(s):  
Nobuo Kato ◽  
Hans J. Eggers ◽  
Heinrich Rolly
Keyword(s):  
Chick Embryo ◽  
Vaccinia Virus ◽  
Inhibitory Effect ◽  
Virus Multiplication ◽  
Kidney Cells ◽  
Virus Release ◽  
Single Cycle ◽  
Infected Cells ◽  
Embryo Fibroblasts ◽  
Intracellular Virus

N1-isonicotinoyl-N2-3-methyl-4-chlorobenzoylhydrazine (IMCBH) is a selective inhibitor of vaccinia virus multiplication. In concentrations up to 50 µg/ml, IMCBH causes neither toxic morphologic changes, nor does it inhibit the multiplication of cells. Viruses other than vaccinia are not affected by IMCBH. The virus-inhibitory effect of IMCBH is dependent on the type of host cell used, i.e., the compound is effective in chick embryo fibroblasts and monkey kidney cells but not in L cells. IMCBH does not exhibit any protecting effect on vaccinia virus-infected mice or rabbits. IMCBH interferes with virus release: in single cycle experiments in chick embryo fibroblasts, IMCBH strongly blocks the release of vaccinia virus at concentrations as low as 3 µg/ml, while intracellular virus synthesis is hardly affected. Viral cytopathic changes are completely suppressed by IMCBH within the span of a single cycle infection, although extensive changes eventually occur. By inhibiting virus release from initially infected cells, IMCBH markedly inhibits the multiplication of vaccinia virus in cell cultures infected at low virus/ cell multiplicities. IMCBH does not inhibit the early toxic cytopathic changes induced by large inocula of vaccinia virus in BHK21 cells.

Reduced steady-state levels of vaccinia virus-specific early mRNAs in interferon-treated chick embryo fibroblasts

Virology ◽  
1987 ◽  
Vol 158 (1) ◽  
pp. 28-33 ◽  
Author(s):  
J. Grün ◽  
E. Kroon ◽  
B. Zoller ◽  
U. Krempien ◽  
C. Jungwirth
Keyword(s):  
Steady State ◽  
Chick Embryo ◽  
Vaccinia Virus ◽  
Steady State Levels ◽  
Embryo Fibroblasts

Regulation of histone H5 and H1° gene expression under the control of vaccinia virus-specific sequences in interferon-treated chick embryo fibroblasts

Virology ◽  
1991 ◽  
Vol 180 (2) ◽  
pp. 535-542 ◽  
Author(s):  
Joachim Grün ◽  
Ingrid Redmann-Müller ◽  
Doris Blum ◽  
Hans-Joachim Degen ◽  
Detlef Doenecke ◽  
...  
Keyword(s):  
Gene Expression ◽  
Chick Embryo ◽  
Vaccinia Virus ◽  
Embryo Fibroblasts ◽  
Histone H5 ◽  
Specific Sequences

scholarly journals Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts

1978 ◽  
Vol 253 (16) ◽  
pp. 5869-5874
Author(s):  
B.H. Howard ◽  
S.L. Adams ◽  
M.E. Sobel ◽  
I. Pastan ◽  
B. de Crombrugghe
Keyword(s):  
Chick Embryo ◽  
Rous Sarcoma Virus ◽  
Collagen Mrna ◽  
Rous Sarcoma ◽  
Sarcoma Virus ◽  
Embryo Fibroblasts
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