scholarly journals The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups

1987 ◽  
Vol 15 (2) ◽  
pp. 397-416 ◽  
Author(s):  
J.C. Schulhof ◽  
D. Molko ◽  
R. Teoule
Keyword(s):  
Protecting Groups ◽  
Oligonucleotide Synthesis ◽  
Ammonia Treatment

ChemInform Abstract: Nucleotide Chemistry. Part 16. Amidine Protecting Groups for Oligonucleotide Synthesis.

1986 ◽  
Vol 17 (32) ◽  
Author(s):  
L. J. MCBRIDE ◽  
R. KIERZEK ◽  
S. L. BEAUCAGE ◽  
M. H. CARUTHERS
Keyword(s):  
Protecting Groups ◽  
Oligonucleotide Synthesis

Oligonucleotide Synthesis Involving Deprotection of Amidine-Type Protecting Groups for Nucleobases under Acidic Conditions

2010 ◽  
Vol 12 (11) ◽  
pp. 2496-2499 ◽  
Author(s):  
Akihiro Ohkubo ◽  
Yasukazu Kuwayama ◽  
Yudai Nishino ◽  
Hirosuke Tsunoda ◽  
Kohji Seio ◽  
...  
Keyword(s):  
Protecting Groups ◽  
Oligonucleotide Synthesis ◽  
Acidic Conditions

scholarly journals Oligonucleotide synthesis using the 2-(levulinyloxymethyl)-5-nitrobenzoyl group for the 5'-position of nucleoside 3'-phosphoramidite derivatives.

1998 ◽  
Vol 45 (4) ◽  
pp. 949-976 ◽  
Author(s):  
K Kamaike ◽  
H Takahashi ◽  
K Morohoshi ◽  
N Kataoka ◽  
T Kakinuma ◽  
...  
Keyword(s):  
Comparative Study ◽  
Protecting Groups ◽  
Protecting Group ◽  
Oligonucleotide Synthesis ◽  
Amino Groups ◽  
Initiator Trna ◽  
15N Labeling

A comparative study on the utility of 2-(levulinyloxymethyl)-5-nitrobenzoyl (LMNBz) and 2-(levulinyloxymethyl)benzoyl (LMBz) protecting groups for the 5'-positions of nucleoside 3'-phosphoramidite derivatives in the oligonucleotide synthesis is presented in terms of the syntheses of TpTpT, TpTpTpT, and UpCpApGpUpUpGpG. In addition we describe the synthesis, using the LMNBz protecting group, of the CpCpA terminus triplet of tRNAs bearing exocyclic amino groups with 15N-labeling, and the trimer Gp[A*]pG containing 2'-O-(beta-D-ribofuranosyl)adenosine ([A*]), the latter of which is found at position 64 in the yeast initiator tRNA(Met).

ChemInform Abstract: Protecting Groups Used in Oligonucleotide Synthesis: A Current Survey

ChemInform ◽  
2010 ◽  
Vol 22 (14) ◽  
pp. no-no
Author(s):  
R. K. SINGH ◽  
A. DIKSHIT ◽  
M. CHADDHA ◽  
G. WATAL ◽  
K. MISRA
Keyword(s):  
Protecting Groups ◽  
Oligonucleotide Synthesis ◽  
Current Survey ◽  
A Current
Sign in / Sign up

Export Citation Format

Share Document