scholarly journals Multiple Paleopolyploidizations during the Evolution of the Compositae Reveal Parallel Patterns of Duplicate Gene Retention after Millions of Years

2008 ◽  
Vol 25 (11) ◽  
pp. 2445-2455 ◽  
Author(s):  
M. S. Barker ◽  
N. C. Kane ◽  
M. Matvienko ◽  
A. Kozik ◽  
R. W. Michelmore ◽  
...  
Keyword(s):  
Duplicate Gene ◽  
Parallel Patterns ◽  
Gene Retention

Knockdown of duplicated zebrafishhoxb1genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention

Development ◽  
2002 ◽  
Vol 129 (10) ◽  
pp. 2339-2354 ◽  
Author(s):  
James M. McClintock ◽  
Mazen A. Kheirbek ◽  
Victoria E. Prince
Keyword(s):  
Protein Function ◽  
Cranial Nerve ◽  
Duplicate Gene ◽  
Regulatory Elements ◽  
Duplicate Genes ◽  
Duplicated Genes ◽  
Gene Retention ◽  
Redundant Functions ◽  
Group 1 ◽  
Rhombomere 4

We have used a morpholino-based knockdown approach to investigate the functions of a pair of zebrafish Hox gene duplicates, hoxb1a and hoxb1b, which are expressed during development of the hindbrain. We find that the zebrafish hoxb1 duplicates have equivalent functions to mouse Hoxb1 and its paralogue Hoxa1. Thus, we have revealed a ‘function shuffling’ among genes of paralogue group 1 during the evolution of vertebrates. Like mouse Hoxb1, zebrafish hoxb1a is required for migration of the VIIth cranial nerve branchiomotor neurons from their point of origin in hindbrain rhombomere 4 towards the posterior. By contrast, zebrafish hoxb1b, like mouse Hoxa1, is required for proper segmental organization of rhombomere 4 and the posterior hindbrain. Double knockdown experiments demonstrate that the zebrafish hoxb1 duplicates have partially redundant functions. However, using an RNA rescue approach, we reveal that these duplicated genes do not have interchangeable biochemical functions: only hoxb1a can properly pattern the VIIth cranial nerve. Despite this difference in protein function, we provide evidence that the hoxb1 duplicate genes were initially maintained in the genome because of complementary degenerative mutations in defined cis-regulatory elements.

scholarly journals Evaluating dosage compensation as a cause of duplicate gene retention in Paramecium tetraurelia

2007 ◽  
Vol 8 (5) ◽  
pp. 213 ◽  
Author(s):  
Timothy Hughes ◽  
Diana Ekman ◽  
Himanshu Ardawatia ◽  
Arne Elofsson ◽  
David A Liberles
Keyword(s):  
Dosage Compensation ◽  
Duplicate Gene ◽  
Paramecium Tetraurelia ◽  
Gene Retention

scholarly journals Generating Configurable Hardware from Parallel Patterns

2016 ◽  
Vol 51 (4) ◽  
pp. 651-665 ◽  
Author(s):  
Raghu Prabhakar ◽  
David Koeplinger ◽  
Kevin J. Brown ◽  
HyoukJoong Lee ◽  
Christopher De Sa ◽  
...  
Keyword(s):  
Parallel Patterns ◽  
Configurable Hardware

Towards On-the-fly Self-Adaptation of Stream Parallel Patterns

2021 ◽  
Author(s):  
Adriano Vogel ◽  
Gabriele Mencagli ◽  
Dalvan Griebler ◽  
Marco Danelutto ◽  
Luiz Gustavo Fernandes
Keyword(s):  
Parallel Patterns ◽  
Self Adaptation

Comparison of Brassica Genomes reveals asymmetrical gene retention between functional groups of genes in recurrent polyploidizations

2021 ◽  
Vol 106 (1-2) ◽  
pp. 193-206
Author(s):  
Haorui Zhang ◽  
Jiandan Xie ◽  
Wenliang Wang ◽  
Jianbo Wang
Keyword(s):  
Functional Groups ◽  
Gene Retention
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