scholarly journals Cytochrome P450 1 Genes in Early Deuterostomes (Tunicates and Sea Urchins) and Vertebrates (Chicken and Frog): Origin and Diversification of the CYP1 Gene Family

2007 ◽  
Vol 24 (12) ◽  
pp. 2619-2631 ◽  
Author(s):  
J. V. Goldstone ◽  
H. M. H. Goldstone ◽  
A. M. Morrison ◽  
A. Tarrant ◽  
S. E. Kern ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Gene Family ◽  
Sea Urchins ◽  
Cyp1 Gene

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

2009 ◽  
Vol 127 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Cristina Rodriguez-Antona ◽  
Alvin Gomez ◽  
Maria Karlgren ◽  
Sarah C. Sim ◽  
Magnus Ingelman-Sundberg
Keyword(s):  
Cytochrome P450 ◽  
Cancer Risk ◽  
Gene Family ◽  
Molecular Genetics ◽  
Cytochrome P450 Gene ◽  
P450 Gene

Comparative aspects of the mammalian cytochrome P450 IV gene family

Xenobiotica ◽  
1989 ◽  
Vol 19 (10) ◽  
pp. 1123-1148 ◽  
Author(s):  
G. Gordon Gibson
Keyword(s):  
Cytochrome P450 ◽  
Gene Family

Isolation and molecular characterisation of the benzoate-para-hydroxylase gene (bphA) of Aspergillus niger: A member of a new gene family of the cytochrome P450 superfamily

1990 ◽  
Vol 223 (2) ◽  
pp. 192-197 ◽  
Author(s):  
Robert F. M. van Gorcom ◽  
Johan G. Boschloo ◽  
Anneke Kuijvenhoven ◽  
Jacqueline Lange ◽  
Arjen J. van Vark ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Aspergillus Niger ◽  
Gene Family ◽  
Molecular Characterisation ◽  
Hydroxylase Gene ◽  
New Gene

scholarly journals The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine

FEBS Letters ◽  
2006 ◽  
Vol 580 (27) ◽  
pp. 6338-6342 ◽  
Author(s):  
Sanjeewa Rupasinghe ◽  
Mary A. Schuler ◽  
Norio Kagawa ◽  
Hang Yuan ◽  
Li Lei ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Gene Family ◽  
Cytochrome P450 Gene ◽  
P450 Gene ◽  
The Absolute

scholarly journals Genome-Wide Analysis of the Cytochrome P450 Gene Family Involved in Salt Tolerance in Gossypium hirsutum

2021 ◽  
Vol 12 ◽  
Author(s):  
Kangtai Sun ◽  
Hui Fang ◽  
Yu Chen ◽  
Zhimin Zhuang ◽  
Qi Chen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Salt Tolerance ◽  
Gossypium Hirsutum ◽  
Gene Family ◽  
Gene Structure ◽  
Transcriptome Analysis ◽  
Upland Cotton ◽  
Chromosomal Localization ◽  
P450 Gene ◽  
Qrt Pcr

Plant cytochrome P450 (P450) participates in a wide range of biosynthetic reactions and targets a variety of biological molecules. These reactions lead to various fatty acid conjugates, plant hormones, secondary metabolites, lignin, and various defensive compounds. In our previous research, transcriptome analysis was performed on the salt-tolerant upland cotton “Tongyan No. 1.” Many differentially expressed genes (DEGs) belong to the P450 family, and their domains occur widely in plants. In this current research, P450 genes were identified in Gossypium hirsutum with the aid of bioinformatics methods for investigating phylogenetic relations, gene structure, cis-elements, chromosomal localization, and collinearity within a genome. qRT-PCR was conducted to analyze P450 gene expression patterns under salt stress. The molecular weights of the 156 P450 genes were in the range of 5,949.6–245,576.3 Da, and the length of the encoded amino acids for all the identified P450 genes ranged from 51 to 2,144. P450 proteins are divided into four different subfamilies based on phylogenetic relationship, gene structure, and chromosomal localization of gene replication. The length of P450 genes in upland cotton differs greatly, ranging from 1,500 to 13,000 bp. The number of exons in the P450 family genes ranged from 1 to 9, while the number of introns ranged from 0 to 8, and there were similar trends within clusters. A total of 31 cis-acting elements were identified by analyzing 1,500 bp promoter sequences. Differences were found in cis-acting elements among genes. The consistency between qRT-PCR and previous transcriptome analysis of salt tolerance DEGs indicated that they were likely to be involved in the salt tolerance of cotton seedlings. Our results provide valuable information on the evolutionary relationships of genes and functional characteristics of the gene family, which is beneficial for further study of the cotton P450 gene family.

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