Isolation and molecular characterisation of the benzoate-para-hydroxylase gene (bphA) of Aspergillus niger: A member of a new gene family of the cytochrome P450 superfamily

1990 ◽  
Vol 223 (2) ◽  
pp. 192-197 ◽  
Author(s):  
Robert F. M. van Gorcom ◽  
Johan G. Boschloo ◽  
Anneke Kuijvenhoven ◽  
Jacqueline Lange ◽  
Arjen J. van Vark ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Aspergillus Niger ◽  
Gene Family ◽  
Molecular Characterisation ◽  
Hydroxylase Gene ◽  
New Gene

scholarly journals Characterization of the pixB gene in Xenorhabdus nematophila and discovery of a new gene family

Microbiology ◽  
2018 ◽  
Vol 164 (4) ◽  
pp. 495-508 ◽  
Author(s):  
John Lucas ◽  
Mary Goetsch ◽  
Matt Fischer ◽  
Steven Forst
Keyword(s):  
Gene Family ◽  
Xenorhabdus Nematophila ◽  
New Gene

scholarly journals Evolutionary history of dimethylsulfoniopropionate (DMSP) demethylation enzyme DmdA in marine bacteria

2019 ◽  
Author(s):  
Laura Hernández ◽  
Alberto Vicens ◽  
Luis Enrique Eguiarte ◽  
Valeria Souza ◽  
Valerie De Anda ◽  
...  
Keyword(s):  
Gene Family ◽  
Evolutionary History ◽  
Common Ancestor ◽  
Functional Divergence ◽  
Gene Families ◽  
Recent Common Ancestor ◽  
Common Ancestry ◽  
Demethylation Pathway ◽  
History Of ◽  
New Gene

ABSTRACTDimethylsulfoniopropionate (DMSP), an osmolyte produced by oceanic phytoplankton, is predominantly degraded by bacteria belonging to the Roseobacter lineage and other marine Alphaproteobacteria via DMSP-dependent demethylase A protein (DmdA). To date, the evolutionary history of DmdA gene family is unclear. Some studies indicate a common ancestry between DmdA and GcvT gene families and a co-evolution between Roseobacter and the DMSP-producing-phytoplankton around 250 million years ago (Mya). In this work, we analyzed the evolution of DmdA under three possible evolutionary scenarios: 1) a recent common ancestor of DmdA and GcvT, 2) a coevolution between Roseobacter and the DMSP-producing-phytoplankton, and 3) pre-adapted enzymes to DMSP prior to Roseobacter origin. Our analyses indicate that DmdA is a new gene family originated from GcvT genes by duplication and functional divergence driven by positive selection before a coevolution between Roseobacter and phytoplankton. Our data suggest that Roseobacter acquired dmdA by horizontal gene transfer prior to exposition to an environment with higher DMSP. Here, we propose that the ancestor that carried the DMSP demethylation pathway genes evolved in the Archean, and was exposed to a higher concentration of DMSP in a sulfur rich atmosphere and anoxic ocean, compared to recent Roseobacter ecoparalogs (copies performing the same function under different conditions), which should be adapted to lower concentrations of DMSP.

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

2009 ◽  
Vol 127 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Cristina Rodriguez-Antona ◽  
Alvin Gomez ◽  
Maria Karlgren ◽  
Sarah C. Sim ◽  
Magnus Ingelman-Sundberg
Keyword(s):  
Cytochrome P450 ◽  
Cancer Risk ◽  
Gene Family ◽  
Molecular Genetics ◽  
Cytochrome P450 Gene ◽  
P450 Gene

scholarly journals pgaE encodes a fourth member of the endopolygalacturonase gene family from Aspergillus niger

1998 ◽  
Vol 251 (1-2) ◽  
pp. 72-80 ◽  
Author(s):  
Lucie Parenicova ◽  
Jacques A. E. Benen ◽  
Harry C. M. Kester ◽  
Jaap Visser
Keyword(s):  
Aspergillus Niger ◽  
Gene Family ◽  
Fourth Member
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