scholarly journals Impacts of Gene Essentiality, Expression Pattern, and Gene Compactness on the Evolutionary Rate of Mammalian Proteins

2007 ◽  
Vol 24 (4) ◽  
pp. 1091-1091
Keyword(s):  
Expression Pattern ◽  
Evolutionary Rate ◽  
Gene Essentiality ◽  
Mammalian Proteins ◽  
Gene Compactness

scholarly journals Impact of Extracellularity on the Evolutionary Rate of Mammalian Proteins

2010 ◽  
Vol 2 ◽  
pp. 39-43 ◽  
Author(s):  
Ben-Yang Liao ◽  
Meng-Pin Weng ◽  
Jianzhi Zhang
Keyword(s):  
Evolutionary Rate ◽  
Mammalian Proteins

scholarly journals A benchmark of gene expression tissue-specificity metrics

2015 ◽  
Author(s):  
Nadezda Kryuchkova ◽  
Marc Robinson-Rechavi
Keyword(s):  
Gene Expression ◽  
Molecular Evolution ◽  
Expression Pattern ◽  
Tissue Specificity ◽  
Evolutionary Rate ◽  
Evolutionary Conservation ◽  
Rna Seq ◽  
Functional Feature ◽  
Tissue Specific

One of the major properties of genes is their expression pattern. Notably, genes are often classified as tissue-specific or housekeeping. This property is of interest to molecular evolution as an explanatory factor of, e.g., evolutionary rate, as well as a functional feature which may in itself evolve. While many different methods of measuring tissue specificity have been proposed and used for such studies, there has been no comparison or benchmarking of these methods to our knowledge, and little justification of their use. In this study we compare nine measures of tissue-specificity. Most methods were established for ESTs and microarrays, and several were later adapted to RNA-seq. We analyze their capacity to distinguish gene categories, their robustness to the choice and number of tissues used, and their capture of evolutionary conservation signal.

Expression pattern of GPR30 in endometriosis

2011 ◽  
Vol 71 (05) ◽  
Author(s):  
EP Samartzis ◽  
N Samartzis ◽  
A Noske ◽  
A Fedier ◽  
R Caduff ◽  
...  
Keyword(s):  
Expression Pattern

Characteristic expression pattern of hypoxia inducible factor 2 alpha mutation-related paragangliomas

2015 ◽  
Vol 122 (03) ◽  
Author(s):  
S Fliedner ◽  
U Shankavaram ◽  
A Elkahloun ◽  
H Lehnert ◽  
K Pacak
Keyword(s):  
Expression Pattern ◽  
Hypoxia Inducible Factor
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