scholarly journals Effects of Piperonyl Butoxide on the Anticholinesterase Activities of Some Organic Phosphorus Insecticides on House Fly and Purified Bovine Erythrocyte Cholinesterases1

1956 ◽  
Vol 49 (5) ◽  
pp. 591-595 ◽  
Author(s):  
Lallan Rai ◽  
C. C. Roan
1973 ◽  
Vol 28 (3-4) ◽  
pp. 107-112 ◽  
Author(s):  
W. Rückert ◽  
K. Ballschmiter

The aspects of molecular-structure and biological conversion have been studied for 12 derivatives of the endosulfan ether 1 [4, 5, 6, 7, 8, 8- hexachloro- 1, 3, 3a, 4, 7, 7a- hexahydro- 4, 7-methanoisobenzofuran]. Adults of a normal house-fly strain (Musca domestica) have been used in the assay. Derivatives of 1 monosubstituted in position I are found to be converted substantially faster than products disubstituted in position I and 3, respectively. Metabolism is inhibited for all compounds studied after application of piperonyl butoxide as a synergist. Besides proving that on oxidative metabolism has to be discussed and in fact could be proved for some derivatives, the intrinsic toxicity of the compounds studied shows up under these conditions. Some derivatives known to be metabolites of the pesticide Endosulfan® show a high intrinsic toxicity to houseflies if the oxidative metabolism is inhibited.


1954 ◽  
Vol 47 (4) ◽  
pp. 701-703
Author(s):  
Robert A. Hoffman ◽  
Nathan W. Cohen

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