scholarly journals Influence of dietary zinc concentration and supplemental zinc source on nutrient digestibility, zinc absorption, and retention in sheep1

2018 ◽  
Vol 96 (12) ◽  
pp. 5336-5344 ◽  
Author(s):  
Katherine R VanValin ◽  
Olivia N Genther-Schroeder ◽  
Remy N Carmichael ◽  
Christopher P Blank ◽  
Erin L Deters ◽  
...  
2010 ◽  
Vol 80 (45) ◽  
pp. 300-306 ◽  
Author(s):  
Janet C. King

Unlike iron, zinc absorption is influenced by dietary zinc intake, not zinc status. As dietary zinc increases, the total amount of absorbed zinc increases while the percent absorbed declines. The gastrointestinal tract maintains whole-body zinc homeostasis by adjusting endogenous zinc losses to the amount absorbed. At intakes below about 9 mg/day, zinc absorption occurs primarily by a saturable (carrier) process involving ZIP4, ZnT1, and other transporters. There is no evidence that past zinc intakes, or status, influences zinc absorption. Instead, current zinc intake is the chief determinant of zinc absorption. Supplemental zinc taken with water in the post-absorptive state initially is absorbed more efficiently than food zinc, but absorption efficiency declines within 24 hours presumably due to down-regulation of the zinc transporters. More research is needed to understand the effect of physiological state on zinc absorption.


1985 ◽  
Vol 5 (1) ◽  
pp. 117-122 ◽  
Author(s):  
Charles R. Brown ◽  
Peter J. Bechtel ◽  
Richard M. Forbes ◽  
Raymond S. Vogel

2016 ◽  
Vol 94 (suppl_2) ◽  
pp. 139-139
Author(s):  
K. E. Jordan ◽  
K. M. Gourley ◽  
M. D. Tokach ◽  
R. D. Goodband ◽  
S. S. Dritz ◽  
...  

2011 ◽  
Vol 141 (7) ◽  
pp. 1369-1374 ◽  
Author(s):  
Grant J. Aaron ◽  
Nafissatou Ba Lo ◽  
Sonja Y. Hess ◽  
Amadou T. Guiro ◽  
Salimata Wade ◽  
...  

Author(s):  
Helena Wall ◽  
Malin Boyner ◽  
Dirk Jan de Koning ◽  
Andreas Kindmark ◽  
Heather A McCormack ◽  
...  

IUBMB Life ◽  
2010 ◽  
Vol 62 (3) ◽  
pp. 176-182 ◽  
Author(s):  
Xiaoxi Wang ◽  
Bing Zhou
Keyword(s):  

1999 ◽  
Vol 77 (7) ◽  
pp. 1788 ◽  
Author(s):  
M Sadoval ◽  
P R Henry ◽  
R C Littell ◽  
R D Miles ◽  
G D Butcher ◽  
...  

1985 ◽  
Vol 31 (4) ◽  
pp. 581-584 ◽  
Author(s):  
P G Reeves ◽  
B L O'Dell

Abstract The activity in serum of zinc-dependent angiotensin converting enzyme (ACE), is measured to aid in diagnosis and monitor treatment of certain diseases. This report shows the effect of dietary zinc deprivation on ACE activity in the serum of rats. The mean (and SE) of the zinc concentration (mumol/L) in serum was 3.5 (0.3) in rats deprived of dietary zinc for four days, 16.3 (0.2) in control rats, and 19.8 (0.9) in rats deprived of zinc for four days, then repleted with zinc for 12 h. The respective mean (and SE) of ACE activities (nmol/mL per min) in serum were 390 (15), 543 (13), and 545 (20). Serum ACE activity was restored also by adding zinc to the assay mixture in vitro. The Vmax for ACE was 1.4 times greater when serum was diluted 40-fold as compared with twofold dilution. There was a small effect on the Km for the substrate, but the Km for zinc was decreased by 22-fold when serum was diluted 40-fold. The Vmax under these conditions was decreased by only 9%.


1958 ◽  
Vol 36 (6) ◽  
pp. 557-569 ◽  
Author(s):  
M. J. Millar ◽  
M. I. Fischer ◽  
P. V. Elcoate ◽  
C. A. Mawson

Dietary zinc deficiency produced by feeding a zinc-poor diet (0.5 μg. zinc per g.) to weanling rats for 8 weeks caused marked retardation in body growth, depressed growth and development of testes, epididymes, accessory sex organs, and pituitary glands, and in many cases severe atrophy of testicular germinal epithelium. The zinc concentration of dorsolateral prostates, testes, epididymes, and bone was reduced in zinc-deficient rats compared with controls receiving the zinc-poor diet plus 100 μg. zinc daily. Restricted feeding of the zinc-supplemented diet to produce body weights comparable to those in zinc-deficient rats caused a reduction in pituitary gland and accessory sex organ size which was similar to that observed in zinc-deficient rats. Testis growth and development were normal in the restricted controls and did not differ from controls fed ad libitum. The zinc concentration of dorsolateral prostates was reduced in restricted controls but exceeded that in the zinc-deficient rats. All the observed changes produced by zinc deficiency except the testicular atrophy were reversed when zinc was replaced in the diet. If testicular atrophy had occurred, neither testis nor epididymis regained normal size, function, or zinc concentration.


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