scholarly journals Dietary zinc absorption: A play of Zips and ZnTs in the gut

IUBMB Life ◽  
2010 ◽  
Vol 62 (3) ◽  
pp. 176-182 ◽  
Author(s):  
Xiaoxi Wang ◽  
Bing Zhou
Keyword(s):  
Zinc Absorption ◽  
Dietary Zinc

Does Zinc Absorption Reflect Zinc Status?

2010 ◽  
Vol 80 (45) ◽  
pp. 300-306 ◽  
Author(s):  
Janet C. King
Keyword(s):  
Physiological State ◽  
Absorption Efficiency ◽  
Zinc Homeostasis ◽  
Zinc Transporters ◽  
Whole Body ◽  
Zinc Absorption ◽  
Zinc Status ◽  
Dietary Zinc ◽  
Zinc Intake ◽  
Supplemental Zinc

Unlike iron, zinc absorption is influenced by dietary zinc intake, not zinc status. As dietary zinc increases, the total amount of absorbed zinc increases while the percent absorbed declines. The gastrointestinal tract maintains whole-body zinc homeostasis by adjusting endogenous zinc losses to the amount absorbed. At intakes below about 9 mg/day, zinc absorption occurs primarily by a saturable (carrier) process involving ZIP4, ZnT1, and other transporters. There is no evidence that past zinc intakes, or status, influences zinc absorption. Instead, current zinc intake is the chief determinant of zinc absorption. Supplemental zinc taken with water in the post-absorptive state initially is absorbed more efficiently than food zinc, but absorption efficiency declines within 24 hours presumably due to down-regulation of the zinc transporters. More research is needed to understand the effect of physiological state on zinc absorption.

Dietary zinc absorption is mediated by ZnT1 in Drosophila melanogaster

2009 ◽  
Vol 23 (8) ◽  
pp. 2650-2661 ◽  
Author(s):  
Xiaoxi Wang ◽  
Yuantai Wu ◽  
Bing Zhou
Keyword(s):  
Drosophila Melanogaster ◽  
Zinc Absorption ◽  
Dietary Zinc

scholarly journals Influence of dietary zinc concentration and supplemental zinc source on nutrient digestibility, zinc absorption, and retention in sheep1

2018 ◽  
Vol 96 (12) ◽  
pp. 5336-5344 ◽  
Author(s):  
Katherine R VanValin ◽  
Olivia N Genther-Schroeder ◽  
Remy N Carmichael ◽  
Christopher P Blank ◽  
Erin L Deters ◽  
...  
Keyword(s):  
Zinc Concentration ◽  
Nutrient Digestibility ◽  
Zinc Absorption ◽  
Dietary Zinc ◽  
Zinc Source ◽  
Supplemental Zinc

scholarly journals Current dietary zinc intake has a greater effect on fractional zinc absorption than does longer term zinc consumption in healthy adult men

2008 ◽  
Vol 87 (5) ◽  
pp. 1224-1229 ◽  
Author(s):  
Carolyn S Chung ◽  
Jodi Stookey ◽  
Doris Dare ◽  
Ross Welch ◽  
Tuan Q Nguyen ◽  
...  
Keyword(s):  
Healthy Adult ◽  
Zinc Absorption ◽  
Dietary Zinc ◽  
Zinc Intake ◽  
Adult Men

scholarly journals Influence of Dairy Products on Bioavailability of Zinc from Other Food Products: A Review of Complementarity at a Meal Level

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4253
Author(s):  
Blerina Shkembi ◽  
Thom Huppertz
Keyword(s):  
Dairy Products ◽  
Food Products ◽  
Zinc Absorption ◽  
Dietary Zinc ◽  
Zinc Intake ◽  
Beneficial Effects ◽  
Dairy Consumption ◽  
Dietary Strategy ◽  
Zinc Sources

In this paper, we reviewed the role of dairy products in dietary zinc absorption. Dairy products can have a reasonable contribution for dietary zinc intake in Western diets, where dairy consumption is high. However, the co-ingestion of dairy products can also improve zinc absorption from other food products. Such improvements have been observed when dairy products (e.g., milk or yoghurt) were ingested together with food such as rice, tortillas or bread products, all of which are considered to be high-phytate foods with low inherent zinc absorption. For foods low in phytate, the co-ingestion of dairy products did not improve zinc absorption. Improved zinc absorption of zinc from high-phytate foods following co-ingestion with dairy products may be related to the beneficial effects of the citrate and phosphopeptides present in dairy products. Considering that the main dietary zinc sources in areas in the world where zinc deficiency is most prevalent are typically high in phytate, the inclusion of dairy products in meals may be a viable dietary strategy to improve zinc absorption.

scholarly journals A Mathematical Model of Zinc Absorption in Humans As a Function of Dietary Zinc and Phytate

2007 ◽  
Vol 137 (1) ◽  
pp. 135-141 ◽  
Author(s):  
Leland V. Miller ◽  
Nancy F. Krebs ◽  
K. Michael Hambidge
Keyword(s):  
Mathematical Model ◽  
Zinc Absorption ◽  
Dietary Zinc

scholarly journals Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability

2008 ◽  
Vol 87 (5) ◽  
pp. 1336-1345 ◽  
Author(s):  
Janet R Hunt ◽  
Jeannemarie M Beiseigel ◽  
LuAnn K Johnson
Keyword(s):  
Zinc Absorption ◽  
Dietary Zinc

scholarly journals Measurement of Zinc Absorption From Meals: Comparison of Extrinsic Zinc Labeling and Independent Measurements of Dietary Zinc Absorption

2009 ◽  
Vol 79 (4) ◽  
pp. 230-237 ◽  
Author(s):  
Xiao-Yang Sheng ◽  
K. Michael Hambidge ◽  
Leland V. Miller ◽  
Jamie E. Westcott ◽  
Sian Lei ◽  
...  
Keyword(s):  
Adult Women ◽  
Zinc Absorption ◽  
Dietary Zinc ◽  
Dual Isotope ◽  
Isotope Tracer ◽  
Wide Range ◽  
Balance Technique ◽  
Living Adult ◽  
Fractional Absorption

Background: Extrinsic labeling techniques are typically used to measure fractional absorption of zinc (FAZextrinsic) but none have been adequately evaluated. Objective: To compare determination of the quantity of zinc absorbed (TAZextrinisic) using measurements of FAZextrinsic with results of simultaneous determinations of dietary zinc absorbed (TAZmetabolic) that are not dependent on labeling ingested food with an extrinsic tracer (modified metabolic balance technique). Design: 70Zn was administered orally with all meals for 6 consecutive days to 21 healthy, free-living adult women consuming a constant diet. 68Zn and 67Zn were administered intravenously. FAZextrinsic was measured using a dual isotope tracer ratio technique and multiplied by dietary zinc to give TAZextrinsic. TAZmetabolic was determined by addition of net absorption of zinc and endogenous fecal zinc, the latter determined by an isotope dilution technique. Results: TAZextrinsic and TAZnetabolic were 3.0 ± 1.1 mg/day and 3.1 ± 1.1 mg/day respectively, paired t-test p = 0.492. The correlation coefficient for TAZextrinsic and TAZmetabolic was 0.91, and for FAZextrinsic and FAZmetabolic was 0.95. A Bland Altman analysis indicated a bias of 0.07, and the limits of agreement of -0.86 to 1.01 for TAZextrinsic and TAZmetabolic. Conclusion: These results from two independent methods provide reasonable validation of our extrinsic labeling technique for a wide range of composite diets.

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