scholarly journals Structural equation modelling of viral tropism reveals its impact on achieving viral suppression within 6 months in treatment-naive HIV-1-infected patients after combination antiretroviral therapy

2016 ◽  
Vol 72 (1) ◽  
pp. 220-226 ◽  
Author(s):  
Carlo Mengoli ◽  
Samantha Andreis ◽  
Renzo Scaggiante ◽  
Mario Cruciani ◽  
Oliviero Bosco ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Structural Equation Modelling ◽  
Structural Equation ◽  
Viral Suppression ◽  
Combination Antiretroviral Therapy ◽  
Viral Tropism ◽  
Equation Modelling ◽  
Treatment Naïve ◽  
Hiv 1

Cost Effectiveness of Darunavir/ritonavir Combination Antiretroviral Therapy for Treatment-Naive Adults with HIV-1 Infection in Canada

2014 ◽  
Vol 32 (9) ◽  
pp. 903-917 ◽  
Author(s):  
Anita J. Brogan ◽  
Erik Smets ◽  
Josephine A. Mauskopf ◽  
Sarah A. L. Manuel ◽  
Ines Adriaenssen
Keyword(s):  
Cost Effectiveness ◽  
Antiretroviral Therapy ◽  
Combination Antiretroviral Therapy ◽  
Treatment Naïve ◽  
Hiv 1

scholarly journals CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import

2021 ◽  
Author(s):  
Julie Janssens ◽  
Jolien Blokken ◽  
Yulia Lampi ◽  
Flore De Wit ◽  
Irena Zurnic Bonisch ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Nuclear Import ◽  
Viral Suppression ◽  
Combination Antiretroviral Therapy ◽  
Viral Loads ◽  
Sustained Viral Suppression ◽  
Induced Mutagenesis ◽  
Hiv 1

Combination antiretroviral therapy (cART) effectively controls HIV-1 by reducing viral loads, but it does not cure the infection. Lifelong treatment with cART is a prerequisite for sustained viral suppression.

Classes of Antiretrovirals

2017 ◽  
Author(s):  
Benjamin Young
Keyword(s):  
Antiretroviral Therapy ◽  
Viral Suppression ◽  
Hiv Protease ◽  
People Living With Hiv ◽  
Hiv Integrase ◽  
Combination Antiretroviral Therapy ◽  
Entry Inhibitors ◽  
Asymptomatic Individuals ◽  
Living With Hiv ◽  
Hiv 1

Results of the randomized, international INSIGHT START clinical trial provide definitive proof of the benefit of antiretroviral therapy initiation in asymptomatic individuals with CD4+ counts greater than 500 cells/mm3. There are six different classes of antiretroviral agents: two types of reverse transcriptase inhibitors, two types of entry inhibitors, one class of inhibitors of HIV protease, and one class of inhibitors of HIV integrase. Combination antiretroviral therapy is recommended for all people living with HIV. The primary goal of combination antiretroviral therapy is to achieve viral suppression. Each antiretroviral class targets a unique step in the replication cycle of HIV-1.

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