scholarly journals Broad anti-HIV activity of the Oscillatoria agardhii agglutinin homologue lectin family

2014 ◽  
Vol 69 (10) ◽  
pp. 2746-2758 ◽  
Author(s):  
Geoffrey Férir ◽  
Dana Huskens ◽  
Sam Noppen ◽  
Leonardus M. I. Koharudin ◽  
Angela M. Gronenborn ◽  
...  
2012 ◽  
Vol 287 (40) ◽  
pp. 33796-33811 ◽  
Author(s):  
Leonardus M. I. Koharudin ◽  
Sireesha Kollipara ◽  
Christopher Aiken ◽  
Angela M. Gronenborn

Structure ◽  
2011 ◽  
Vol 19 (8) ◽  
pp. 1170-1181 ◽  
Author(s):  
Leonardus M.I. Koharudin ◽  
Angela M. Gronenborn

2015 ◽  
Vol 9 (2) ◽  
pp. 317-319 ◽  
Author(s):  
Marta G. Carneiro ◽  
Leonardus M. I. Koharudin ◽  
Christian Griesinger ◽  
Angela M. Gronenborn ◽  
Donghan Lee

Author(s):  
A.S. Dabholkar ◽  
W.W. Carmichael ◽  
K. Berg ◽  
J. Wyman

Intracellular changes in the hepatocytes of isolated rat livers perfused with cyclic heptapeptide toxins are described. The toxins used are 1) -Ala-Leu- β-methyl isoAsp-Arg-ADDA-isoGlu-mdha (M.W. 944) from Microcystis aeruginosa- Lake Akersvatn, Norway; 2) -Ala-Arg-isoAsp-Arg-ADDA-isoGlu-mdha (M.W. 1023) from Oscillatoria agardhii var. - Lake Kolbatnvatn, Norway; 3) -Ala-Arg-isoAsp-Arg-ADDA-isoGlu-dha (M.W. 1009) from Oscillatoria agardhii var. isothrix - Lake Froylandsvatn, Norway. Approximate LD intraperitoneal mouse for the toxins is 50, 500 and 1000 μg/kg respectively.Livers were removed from male Sprague Dawley rats and perfused for 15 min with a blood-free perfusate (50 ml) followed by 60 min with perfusate containing i) 25, 50, or 200 μg of M. aeruginosa toxin ii) 50, 250, 500 or 1000 μg of O. agardhii var. toxin and iii) 1000, 2000, 2500 or 5000 μg of O. agardhii var. isothrix toxin. Control livers were perfused for 75 min with the blood-free perfusate.


Nature ◽  
2010 ◽  
Author(s):  
Rebecca Trager
Keyword(s):  

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