scholarly journals Public health need versus sales of antibacterial agents active against multidrug-resistant bacteria: a historical perspective

2013 ◽  
Vol 69 (4) ◽  
pp. 1151-1153 ◽  
Author(s):  
D. L. Monnet ◽  
J. Giesecke
Keyword(s):  
Public Health ◽  
Historical Perspective ◽  
Antibacterial Agents ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Health Need

Polymicrobial multidrug-resistant bacteria isolated from street vended fresh fruit juices in Pakistan

2018 ◽  
Vol 120 (6) ◽  
pp. 1358-1365
Author(s):  
Muhammad Hussnain Siddique ◽  
Muhammad Usman Qamar ◽  
Sumreen Hayat ◽  
Bilal Aslam ◽  
Habibullah Nadeem ◽  
...  
Keyword(s):  
Public Health ◽  
Multidrug Resistant ◽  
Fruit Juices ◽  
Fresh Fruit ◽  
Resistant Bacteria ◽  
Local Market ◽  
Multidrug Resistant Bacteria ◽  
Content Type ◽  
Preliminary Identification ◽  
Surface Spread

Purpose The purpose of this paper is to evaluate the prevalence and antibiograms of bacteria isolated from various fresh fruit juices at a local market in Faisalabad. Design/methodology/approach Fresh fruit juice samples (n=125) were randomly collected using aseptic technique. Each sample (10 mL) was serially diluted with 90 mL of sterile peptone water, from 1×10−1 to 1×10−5. Each dilution was then used to inoculate nutrient agar by surface spread plating. Aerobic colony counts (ACCs) were determined by colony counting. The isolates were sub-cultured on blood and MacConkey agar. Preliminary identification was achieved on the basis of colony morphology and culture characteristic, and confirmed by API® 20E, 20NE, and API® Staph testing. Antimicrobial susceptibility testing was carried out using the Kirby-Bauer disk diffusion assay, per CLSI 2015 guidelines. Findings The mean ACC ranged from 2.0×106 CFU/mL to 4.93×106 CFU/mL, with the highest ACC determined for orange juice. Overall, 153 polymicrobial were identified in 125 samples; 103 of these were Gram-negative rods (GNR) and 28 were Gram-positive cocci (GPC). Escherichia coli (n=38), Klebsiella pneumoniae (n=32) and Pseudomonas aeruginosa (n=24) were the predominant GNR; Staphylococcus aureus (n=28) was the predominant GPC. Antibiogram analysis revealed that all GNR were resistant to ampicillin. However, most E. coli isolates were resistant to ceftazidime (72.4 percent of isolates), and ceftriaxone and cefepime (68.9 percent), while most K. pneumoniae isolates were resistant to cefepime (72 percent) and ceftriaxone (64 percent). All S. aureus isolates were resistant to penicillin, while most (64 percent) were resistant to piperacillin; the most effective drugs against bacteria were vancomycin and imipenem. Practical implications The findings suggest that the local government regulatory food and public health authorities should take immediate emergency measures. Appropriate surveillance studies and periodic monitoring of food items should be regularly performed to safeguard public health. Originality/value The current study revealed the prevalence of multidrug-resistant bacteria in freshly prepared fruit juices sold by local street vendors.

Hospital liquid waste contaminated with multidrug-resistant bacteria raises a public health hazard alert in Brazil

2021 ◽  
Vol 193 (11) ◽  
Author(s):  
Leila Lúcia Dias ◽  
Rafael Nakamura-Silva ◽  
Gilberto André Teles de Oliveira Junior ◽  
Ivan Orlando Gonzales Mego ◽  
Guilherme Silva Mendonça ◽  
...  
Keyword(s):  
Public Health ◽  
Health Hazard ◽  
Liquid Waste ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria

scholarly journals Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections

2021 ◽  
Vol 7 (8) ◽  
pp. 112
Author(s):  
Lingchao Xiang ◽  
Ozioma Udochukwu Akakuru ◽  
Chen Xu ◽  
Aiguo Wu
Keyword(s):  
Public Health ◽  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Public Health Problem ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Bacterial Detection ◽  
Prevention And Treatment ◽  
Further Development

Infections caused by pathogenic bacteria, especially multidrug-resistant bacteria, have become a serious worldwide public health problem. Early diagnosis and treatment can effectively prevent the adverse effects of such infections. Therefore, there is an urgent need to develop effective methods for the early detection, prevention, and treatment of diseases that are caused by bacterial infections. So far, magnetic material nanoparticles (MNPs) have been widely used in the detection and treatment of bacterial infections as detection agents and therapeutics. Therefore, this review describes the recent research on MNPs in bacterial detection and treatment. Finally, a brief discussion of challenges and perspectives in this field is provided, which is expected to guide the further development of MNPs for bacterial detection and treatment.

Cholesteroled polymer (Chol-b-Lys)-based nanoparticles (CL-NPs) confer antibacterial efficacy without resistance

2021 ◽  
Author(s):  
Ke-Wu Yang ◽  
Huan-Huan Ding ◽  
Jia-Zhu Chigan ◽  
Jian-Bin Zhen ◽  
Lu Liu ◽  
...  
Keyword(s):  
Antibacterial Agents ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Antibacterial Efficacy ◽  
Multidrug Resistant Bacteria

It is imperative to develop innovative and efficient antibacterial agents, on account of the mounting prevalence of complicated infections induced by multidrug-resistant bacteria. In this work, Chol-b-Lys nanoparticles (CL-NPs) with...

scholarly journals “Infectious Supercarelessness” in Discussing Antibiotic-Resistant Bacteria

2016 ◽  
Vol 1 (2) ◽  
pp. 304 ◽  
Author(s):  
Neil S. Greenspan
Keyword(s):  
Public Health ◽  
Full Range ◽  
Multidrug Resistant ◽  
Health Interventions ◽  
Resistant Bacteria ◽  
Public Health Interventions ◽  
Multidrug Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Evolutionary Context ◽  
The Media

Many bacterial pathogens are exhibiting resistance to increasing numbers of antibiotics making it much more challenging to treat the infections caused by these microbes. In many reports in the media and perhaps even in discussions among physicians and biomedical scientists, these bacteria are frequently referred to as “bugs” with the prefix “super” appended. This terminology has a high potential to elicit unjustified inferences and fails to highlight the broader evolutionary context. Understanding the full range of biological and evolutionary factors that influence the spread and outcomes of infections is critical to formulating effective individual therapies and public health interventions. Therefore, more accurate terminology should be used to refer these multidrug-resistant bacteria. 

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