A double-blinded comparative study of sultamicillin and potassium penicillin V in the treatment of childhood streptococcal pharyngitis*

1984 ◽  
Vol 14 (3) ◽  
pp. 261-265 ◽  
Author(s):  
Stephen C. Aronoff ◽  
Jeffrey D. Klinger ◽  
Cheryl A. O'Brien ◽  
Arthur C. Jaffe ◽  
Jeffrey L. Blumer
PEDIATRICS ◽  
1963 ◽  
Vol 31 (1) ◽  
pp. 22-28
Author(s):  
Maxwell Stillerman ◽  
Stanley H. Bernstein ◽  
Martha Smith ◽  
Jack D. Gorvoy

The relative effectiveness of erythromycin propionate and K penicillin V in two dosage schedules was evaluated in the treatment of 261 cases of acute pharyngitis from which Group A hemolytic streptococci were recovered from December, 1958, to June, 1959. Erythromycin propionate, in a daily dose of 30 mg/kg up to 1.0 gm, and K penicillin V, in daily doses of 375 mg and 750 mg, were administered orally for 10 days. The adjusted bacterial cure rate was 78% among 86 patients treated with erythromycin, 72% among 102 patients treated with K penicillin V, 375 mg, and 88% among 73 patients treated with K penicillin V, 750 mg. The data indicate that K penicillin V was more effective in eradicating Group A streptococci from the pharynx in a daily dose of 750 mg than 375 mg, and suggest that erythromycin propionate in the dosage used, was less effective than K penicillin V, 750 mg, but equally as effective as K penicillin V, 375 mg daily. The incidence, time of occurrence, and results of retreatments of bacterial relapses are presented, and two possible causes of relapses are considered.


1998 ◽  
Vol 37 (6) ◽  
pp. 341-346 ◽  
Author(s):  
Ishwar Gopichand ◽  
Gary D. Williams ◽  
Carla Saracusa ◽  
Sharon V. Medendorp ◽  
Camille Sabella ◽  
...  

Chemotherapy ◽  
1992 ◽  
Vol 38 (2) ◽  
pp. 33-37 ◽  
Author(s):  
J. Ramet ◽  
D. Pierard ◽  
P. Vandenberghe ◽  
K. De Boeck

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