Vedolizumab Induced Clinical, Endoscopic, and Histological Improvement in Common Variable Immunodeficiency Disease–associated Intestinal Enteropathy

2020 ◽  
Vol 26 (4) ◽  
pp. e22-e23 ◽  
Author(s):  
Hisham Javed Akhtar ◽  
Bharat Markandey ◽  
Christopher Ma ◽  
Darryl Ramsewak ◽  
Joanna C Walsh ◽  
...  

After treatment with vedolizumab, a patient with diarrhea and malnutrition secondary to common variable immune deficiency (CVID)–related enteropathy was able to achieve clinical, endoscopic, and histological improvement. Vedolizumab may be a treatment option for patients with CVID-associated enteropathy.

Blood ◽  
2019 ◽  
Vol 134 (21) ◽  
pp. 1787-1795 ◽  
Author(s):  
Charlotte Cunningham-Rundles

In this review, the authors describe 3 patients with common variable immunodeficiency (CVID), noting the disease manifestations most relevant to the practicing hematologist, especially autoimmune cytopenias, benign lymphoproliferation, granulomatous disease, and lymphomas such as common noninfectious complications of CVID.


2013 ◽  
Vol 10 (1) ◽  
pp. 58-61
Author(s):  
E A Latysheva

Primary immunodeficiencies (PID) occur more often than we used to think. Due to the low awareness of physicians about this disease, from the onset of symptoms to diagnosis patients are difficult path, often measured in years. In PID adults the most common is humoral immunity disorder. Given the wide range of clinical phenotypes of the disease, immunologist may be far from the GP during diagnosis. The article presents a case of a patient with common variable immune deficiency, that was masked under the brain tumor.


1986 ◽  
Vol 3 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Daphne Morrell ◽  
Charles L. Chase ◽  
Michael Swift ◽  
D. C. Rao

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