scholarly journals Is smoking a risk factor for decreased semen quality? A cross-sectional analysis

2006 ◽  
Vol 22 (1) ◽  
pp. 188-196 ◽  
Author(s):  
C.H. Ramlau-Hansen ◽  
A.M. Thulstrup ◽  
A.S. Aggerholm ◽  
M.S. Jensen ◽  
G. Toft ◽  
...  
Keyword(s):  
Risk Factor ◽  
Semen Quality ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

Hyperfiltration Is a Risk Factor For The Development Of Microalbuminuria In Sickle Cell Anemia

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 1003-1003
Author(s):  
Benjamin Vazquez ◽  
Santosh L. Saraf ◽  
Robert E. Molokie ◽  
Michel Gowhari ◽  
Johara Hassan ◽  
...  
Keyword(s):  
Risk Factor ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Red Blood Cell Transfusion ◽  
Common Finding ◽  
Albumin Concentration ◽  
Cross Sectional ◽  
Hemoglobin F ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

Abstract Hyperfiltration, which has been implicated in the early stages of development of chronic kidney disease (CKD) in diabetes mellitus, is a common finding in sickle cell anemia (SCA) patients with normal kidney function. We hypothesized that it may be a risk factor for the development of microalbuminuria, an early indicator of glomerular injury that is observed in 40-60% of adult patients with sickle cell anemia (SCA). In the cross-sectional analysis, 233 adult SCA patients treated at the University of Illinois at Chicago Sickle Cell Center with baseline estimated glomerular filtration rates (eGFR) determined by the MDRD equation and albuminuria concentrations were screened. Data was collected from steady-state visits defined as four weeks from a vaso-occlusive pain episode or red blood cell transfusion. Eight-two patients with normoalbuminuria (urine albumin concentration < 30mg/g creatinine) and an eGFR ≥ 90mL/min/1.73m2 were evaluated of which 38 (46%) had normal eGFR (defined as eGFR 90-150mL/min/1.73m2) and 44 (54%) had hyperfiltration (defined as eGFR >150mL/min/1.73 m2). On univariate analysis, the median age of patients with hyperfiltration was 23 years compared to 34 years in patients with a normal eGFR (p<0.0001). Additionally, patients with hyperfiltration had lower hemoglobin F concentrations (3.9 vs. 7.3%, p=0.01) and higher absolute reticulocyte counts (390 vs. 288 x103/µL, p=0.03) than patients with normal eGFR, respectively. On multivariate analysis, hyperfiltration was independently associated with age (OR 0.9, 95% CI: 0.8-0.9; p=0.0001) and the natural log of hemoglobin F concentration (OR 0.5, 95% CI: 0.2-1.0; p=0.04). Forty-six patients with normoalbuminuria and eGFR ≥ 90mL/min/1.73m2 were followed longitudinally for progression to microalbuminuria. At a median follow up of 30 months (range 1-81 months), 35% (16/46) of patients developed microalbuminuria with a mean time to progression of 49 months (range 11-57 months). The average time to develop microalbuminuria in patients with hyperfiltration was 33 months (42%, 11/26) compared to 62 months in patients with normal eGFR (25%, 5/20) (age-adjusted HR 4.0, 95% CI 1.5 – 10.4; log-rank p=0.016) (Figure 1). In summary, hyperfiltration in SCA patients with normoalbuminuria was associated with younger age and lower hemoglobin F concentration on cross sectional analysis and with higher rates of progression to microalbuminuria on longitudinal analysis. Future research to better understand the development of hyperfiltration and its contribution to kidney damage may help guide future therapies for sickle cell nephropathy. Disclosures: No relevant conflicts of interest to declare.

Dental Caries in HIV-seropositive Women

2004 ◽  
Vol 83 (11) ◽  
pp. 869-873 ◽  
Author(s):  
J.A. Phelan ◽  
R. Mulligan ◽  
E. Nelson ◽  
J. Brunelle ◽  
M.E.A.F. Alves ◽  
...  
Keyword(s):  
Risk Factor ◽  
Dental Caries ◽  
Hiv Infection ◽  
Root Caries ◽  
Caries Prevalence ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Hiv Women ◽  
Sectional Analysis ◽  
Hiv Seropositive

Reports that compare dental caries indices in HIV-seropositive (HIV+) subjects with HIV-seronegative (HIV-) subjects are rare. The objective of this study was to determine if there was an association between HIV infection and dental caries among women enrolled in the Women’s Interagency HIV Study. Subjects included 538 HIV+ and 141 HIV- women at baseline and 242 HIV+ and 66 HIV- women at year 5. Caries indices included DMFS and DFS (coronal caries) and DFSrc (root caries). Cross-sectional analysis of coronal caries data revealed a 1.2-fold-higher caries prevalence among HIV+ women compared with HIV- women. Longitudinally, DMFS increased with increasing age and lower average stimulated salivary volume. Root caries results were not significant except for an overall increased DFSrc associated with smoking. Anti-retroviral therapy was not identified as a risk factor for dental caries.

scholarly journals Mediterranean diet and the risk of poor semen quality: cross‐sectional analysis of men referring to an Italian Fertility Clinic

Andrology ◽  
2019 ◽  
Vol 7 (2) ◽  
pp. 156-162 ◽  
Author(s):  
E. Ricci ◽  
F. Bravi ◽  
S. Noli ◽  
S. Ferrari ◽  
V. De Cosmi ◽  
...  
Keyword(s):  
Mediterranean Diet ◽  
Semen Quality ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Fertility Clinic ◽  
Sectional Analysis

scholarly journals Antioxidant Vitamins and Carotenoids Intake and the Association With Poor Semen Quality: A Cross-Sectional Analysis of Men Referring to an Italian Fertility Clinic

2021 ◽  
Vol 8 ◽  
Author(s):  
Valentina De Cosmi ◽  
Fabio Parazzini ◽  
Carlo Agostoni ◽  
Stefania Noli ◽  
Sonia Cipriani ◽  
...  
Keyword(s):  
Randomized Clinical Trials ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Health History ◽  
Semen Volume ◽  
Sectional Analysis ◽  
Β Carotene

Several studies suggested that male's diet affects fertility. This cross-sectional analysis from a prospective cohort study aims to explore the relation between antioxidants intake and sperm parameters in sub-fertile couples referring to a Fertility center. Socio-demographic characteristics, health history, lifestyle habits, and diet information were obtained. A semen sample was analyzed to proceed with assisted reproduction. Three hundred and twenty-three men were enrolled: 19.1% had semen volume (SV) &lt; 1.5 mL, 31.4% sperm concentration (SC) &lt; 15.0 mil/mL, 26.8% sperm motility &lt; 32%, and 33.0% had total sperm count (TSC) &lt; 39.0 mil. Higher levels of α-carotene were associated to lower risk of low SC [4th vs. 1st quartile, adjusted OR (aOR) 0.43, 95% CI 0.20–0.91) and low TSC (aOR 0.46, 95% CI 0.22–0.95). Higher intake of β-carotene was inversely associated with risk of low TSC. Lycopene intake was associated with higher risk for these conditions (aOR 2.46, 95%CI 1.01–5.98, SC), and (aOR 3.11, 95%CI 1.29–7.50, TSC). Risk of low semen volume was lower in men with higher level of vitamin D intake (aOR 0.25, 95%CI 0.09–0.66)]. Further research, especially, well-designed randomized clinical trials (RCT), is needed to understand how diet modifications may have a role in modulating male fertility and fecundability.

Evaluation of the prevalence and nutritional and social determinants of overweight in a population of schoolchildren: a cross-sectional analysis of 5,037 children

2012 ◽  
Vol 58 (4) ◽  
pp. 472-476 ◽  
Author(s):  
Caroline Filla Rosaneli ◽  
Flavia Auler ◽  
Carla Barreto Manfrinato ◽  
Claudine Filla Rosaneli ◽  
Caroline Sganzerla ◽  
...  
Keyword(s):  
Social Determinants ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis
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