scholarly journals Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality

2005 ◽  
Vol 20 (10) ◽  
pp. 2776-2783 ◽  
Author(s):  
Jiri Rubes ◽  
Sherry G. Selevan ◽  
Donald P. Evenson ◽  
Dagmar Zudova ◽  
Miluse Vozdova ◽  
...  
Keyword(s):  
Air Pollution ◽  
Dna Fragmentation ◽  
Semen Quality ◽  
Human Sperm

scholarly journals Melatonin and Caffeine Supplementation Used, Respectively, as Protective and Stimulating Agents in the Cryopreservation of Human Sperm Improves Survival, Viability, and Motility after Thawing compared to Traditional TEST-Yolk Buffer

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Juliana R. Pariz ◽  
Caroline Ranéa ◽  
Rosa A. C. Monteiro ◽  
Donald P. Evenson ◽  
Joël R. Drevet ◽  
...  
Keyword(s):  
Dna Fragmentation ◽  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Concentration ◽  
Human Sperm ◽  
Mitochondrial Activity ◽  
Ros Production ◽  
Stimulant Effect ◽  
Progressive Motility ◽  
Before And After

Cryopreservation processes can damage spermatozoa and impair structural and functional cell characteristics. Plasma, nuclear membranes, and cellular organelles can suffer from the freeze and thaw process. This study evaluates the protective and stimulant effect of melatonin and caffeine supplementation on the functional characteristics of human spermatozoa before and after freezing. Thirty seminal samples from normozoospermic men aged 19–45 years old collected between October 2012 and May 2017 were included. Semen samples were supplemented with either 2 mM melatonin (MEL) prior to cryopreservation, 2 mM caffeine (CAF) in postthaw, or CAF and MEL (CM) in precryopreservation and postthaw, respectively. Kinetics and seminal parameters, mitochondrial activity, DNA fragmentation, and reactive oxygen species (ROS) levels were analyzed before and after cryopreservation. A significant reduction in sperm concentration, total and progressive motility, sperm kinetics, and mitochondrial activity, as well as a significant increase in DNA fragmentation and ROS production in postthaw samples compared to fresh samples, was identified. After administration of a caffeine and/or melatonin supplement, there was a significant increase in progressive motility in the CAF (p=0.005) and CM (p=0.048) groups, as well as mitochondrial activity in the CM group (p<0.05). Cryopreservation has negative effects on overall sperm quality and increases ROS production. A combination of caffeine and melatonin in prefreeze and postthaw sperm samples has proven to be a very effective and simple way to improve semen quality. This will be particularly useful for initial low-quality semen samples, those which suffer the most from the freezing/thawing process.

Use of laptop computers connected to internet through Wi-Fi decreases human sperm motility and increases sperm DNA fragmentation

2012 ◽  
Vol 97 (1) ◽  
pp. 39-45.e2 ◽  
Author(s):  
Conrado Avendaño ◽  
Ariela Mata ◽  
César A. Sanchez Sarmiento ◽  
Gustavo F. Doncel
Keyword(s):  
Dna Fragmentation ◽  
Sperm Motility ◽  
Human Sperm ◽  
Sperm Dna Fragmentation ◽  
Laptop Computers ◽  
Sperm Dna

Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility

2004 ◽  
Vol 82 (4) ◽  
pp. 871-877 ◽  
Author(s):  
T SAID ◽  
A AGARWAL ◽  
R SHARMA ◽  
E MASCHA ◽  
S SIKKA ◽  
...  
Keyword(s):  
Male Infertility ◽  
Superoxide Anion ◽  
Semen Quality ◽  
Human Sperm ◽  
Superoxide Anion Generation

DETERMINATION OF THE HUMAN SPERM DNA FRAGMENTATION INDEX

Vestnik ◽  
2021 ◽  
pp. 226-232
Author(s):  
К. К. Тлеуханов ◽  
Н. А. Алтыбаева ◽  
М. К. Отарбаев ◽  
Е. М. Тойшибеков ◽  
А. А. Тлеуханова
Keyword(s):  
Dna Fragmentation ◽  
Human Sperm ◽  
Sperm Dna Fragmentation ◽  
Fragmentation Index ◽  
Sperm Dna ◽  
Sperm Dna Fragmentation Index ◽  
Dna Fragmentation Index

В статье представлены собранные данные о методах устранения повышенной частоты фрагментации ДНК у сперматозоидов, которые в некоторых исследованиях подтверждают, что введение антиоксидантов может снизить уровень фрагментации ДНК у сперматозоидов. The article presents collected data on methods of eliminating the increased frequency of DNA fragmentation in spermatozoa, which in some studies confirm that the introduction of antioxidants can reduce the level of DNA fragmentation in spermatozoa.

scholarly journals Exposures to air pollution and endocrine disruptors and measures of semen quality in a population based cohort of US men

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
J.E. Hart ◽  
I. Holland ◽  
S. Gillooly ◽  
G. Adamkiewicz ◽  
K.A. Anderson ◽  
...  
Keyword(s):  
Air Pollution ◽  
Endocrine Disruptors ◽  
Semen Quality ◽  
Population Based
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