scholarly journals CYTOLOGICAL IDENTIFICATION OF THE CHROMOSOMES INVOLVED IN SEARLE'S TRANSLOCATION AND THE LOCATION OF THE CENTROMERE IN THE X CHROMOSOME OF THE MOUSE

Genetics ◽  
1972 ◽  
Vol 71 (4) ◽  
pp. 643-648
Author(s):  
Eva M Eicher ◽  
Muriel N Nesbitt ◽  
Uta Francke
Keyword(s):  
Linkage Group ◽  
X Chromosome ◽  
Chromosome 16 ◽  
Autosome Translocation ◽  
Group Xv

ABSTRACT The autosome in Searle's X-autosome translocation has been shown to be chromosome 16. The breakpoint in chromosome 16 is slightly proximal to the middle and in the X is slightly distal to the middle.—Available evidence indicates that either Linkage Group XV or Linkage Group XIX is carried on chromosome 16.—The centromere of the X chromosome is at the spf end of the linkage group.

scholarly journals The location of Cattanach's translocation in the X-chromosome linkage map of the mouse

1966 ◽  
Vol 8 (2) ◽  
pp. 253-256 ◽  
Author(s):  
B. M. Cattanach
Keyword(s):  
Linkage Group ◽  
Linkage Map ◽  
X Chromosome ◽  
Present Communication ◽  
Group I ◽  
Autosome Translocation

In Cattanach's X-autosome translocation a piece of autosome of linkage group I has been inserted into the X-chromosome and a piece of X may have been reciprocally translocated to the autosome (Cattanach, 1961; Ohno & Cattanach, 1962). The present communication reports investigations to locate the autosomal insertion in the X-chromosome linkage map and provide evidence pertinent to the question of the possible reciprocal nature of the rearrangement; a brief summary of the results has already been reported (Cattanach & Isaacson, 1965).

scholarly journals Development of a bovine X chromosome linkage group and painting probes to assess cattle, sheep, and goat X chromosome segment homologies.

1996 ◽  
Vol 93 (8) ◽  
pp. 3450-3454 ◽  
Author(s):  
F. A. Ponce de Leon ◽  
S. Ambady ◽  
G. A. Hawkins ◽  
S. M. Kappes ◽  
M. D. Bishop ◽  
...  
Keyword(s):  
Linkage Group ◽  
X Chromosome ◽  
Chromosome Segment ◽  
Painting Probes

Genetics of the tsetse fly Glossina morsitans submorsitans Newstead (Diptera: Glossinidae): further mapping of linkage groups I, II, and III

1999 ◽  
Vol 77 (8) ◽  
pp. 1309-1313 ◽  
Author(s):  
R H Gooding ◽  
C M Challoner
Keyword(s):  
Linkage Group ◽  
X Chromosome ◽  
Aldehyde Oxidase ◽  
Female Offspring ◽  
Tsetse Fly ◽  
Glossina Morsitans ◽  
Group Iii ◽  
Glossina Morsitans Submorsitans ◽  
Group I ◽  
Group Ii

Standard mapping procedures were used to map four loci in linkage group I (the X chromosome), two loci in linkage group II, and two loci in linkage group III of Glossina morsitans submorsitans. In the presence of the allele Srd (the distorter allele favoring production of female offspring), no recombination occurred between any of the following loci: Pgm (phosphoglucomutase), wht (white eye color), Est-X (a thoracic esterase), and Sr (sex-ratio distortion). However, in the absence of Srd (i.e., in females homozygous for Srn, the allele that permits males to sire both female and male offspring in approximately equal numbers), the loci Pgm and wht were separated by 23 ± 4.0% recombination (map distance). These results indicate that ourG. m. submorsitans strains carry two forms of the X chromosome, designated XA and XB. In support of this interpretation, two lines of G. m. submorsitans were established: in both lines, males with wild-type eyes sired families that were almost exclusively female, while males with white eyes sired families having males and females in approximately equal numbers. Two loci, Ao (aldehyde oxidase) and Est-1 (a thoracic esterase) were separated by 6.1 ± 2.3% recombination in linkage group II, and two loci, Mdh (malate dehydrogenase) and Pgi (phosphoglucose isomerase), showed 51.9 ± 4.9% recombination in linkage group III.

GENETICS OF GLOSSINA MORSITANS MORSITANS (DIPTERA: GLOSSINIDAE). V. DEFINITION AND PRELIMINARY MAPPING OF LINKAGE GROUPS I AND II

1981 ◽  
Vol 23 (3) ◽  
pp. 399-403 ◽  
Author(s):  
R. H. Gooding
Keyword(s):  
Linkage Group ◽  
X Chromosome ◽  
Aldehyde Oxidase ◽  
Glossina Morsitans Morsitans ◽  
Linkage Groups ◽  
Glossina Morsitans ◽  
Eye Color ◽  
Group I ◽  
Octanol Dehydrogenase ◽  
Differential Part

Linkage group I is defined as the loci on the differential part of the X-chromosome of adult Glossina morsitans morsitans Westwood. Three loci are known and their order on the X-chromosome has been demonstrated as ocra (body color), salmon (eye color), and Apk (arginine phosphokinase, E.C. 2.7.3.3) with 38 map units separating the first two loci and 32 to 41 separating the second two. This region of the X-chromosome does not contain the chromosomal inversion known to occur in the Handeni line of G. m. morsitans. Linkage group II is defined as the autosome carrying the locus Xo (xanthine oxidase, E.C. 1.2.3.2), and it is demonstrated to carry also the loci Ao (aldehyde oxidase, E.C. 1.2.3.1) and Odh (octanol dehydrogenase, E.C. 1.1.1.73). Ao and Odh are within 0.36 map units of each other and have not been separated by recombination; this pair of loci occur about 48 map units from Xo. During mapping experiments, no evidence for genetical recombination was found in male G. m. morsitans.

Genetic activity at the albino locus in Cattanach's insertion in the mouse

Development ◽  
1986 ◽  
Vol 96 (1) ◽  
pp. 295-302
Author(s):  
M. S. Deol ◽  
Gillian M. Truslove ◽  
Anne McLaren
Keyword(s):  
X Chromosome ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
The Other ◽  
Normal Allele ◽  
Cell Type ◽  
Direct Examination ◽  
Autosome Translocation ◽  
Genetic Activity ◽  
Preferential Inactivation

Cattanach's insertion (Is(In7;X)1Ct or XCt) includes the normal allele at the albino locus (c+), which is subject to inactivation of the X chromosome carrying it, so that XCtX; c c mice have albino and pigmented patches. The X-autosome translocation T(X;16)16H or XT16H leads to preferential inactivation of the other X chromosome in female cells, so that XCtXT16H; c c mice are almost entirely white. However, they grow darker with age, as if reversal of inactivation of the c+ allele were taking place in increasing numbers of melanocytes. To test whether this is dependent only on age or whether it is related to the number of times the animal has moulted, hair was repeatedly plucked from selected areas at the early telogen stage when the follicles are also removed, assuming that the melanocytes or melanoblasts in that region of the skin would be forced to undergo further divisions to colonize the new follicles. The plucked areas grew darker at the same rate as the rest of the coat, suggesting that the progressive reversal of inactivation is dependent only on age. As direct examination of melanocytes in the follicles is difficult, they were examined in the choroid and the retinal pigment epithelium (RPE) of the eye. The frequency of the pigmented cells was lower in the choroid than in the RPE. Since the melanocytes in these structures are different in origin as well as in physical characteristics, it appears that cell type influences either reversal of inactivation, or the frequency with which the influence of the X chromosome extends to the albino locus.

Different patterns of X chromosome inactivity in lymphocytes and fibroblasts of a human balanced X; autosome translocation

1982 ◽  
Vol 60 (2) ◽  
pp. 126-129 ◽  
Author(s):  
Bernard Hellkuhl ◽  
Albert de la Chapelle ◽  
Karl-Heinz Grzeschik
Keyword(s):  
X Chromosome ◽  
Autosome Translocation

scholarly journals DUPLICATIONS IN CAENORHABDITIS ELEGANS

Genetics ◽  
1979 ◽  
Vol 92 (2) ◽  
pp. 419-435
Author(s):  
Robert K Herman ◽  
James E Madl ◽  
Claire K Kari
Keyword(s):  
Caenorhabditis Elegans ◽  
Linkage Group ◽  
X Chromosome ◽  
Linkage Groups ◽  
Group V ◽  
Chromosome Map ◽  
Mitotic Instability ◽  
X Irradiation ◽  
Group Ii ◽  
Map Data

ABSTRACT Thirteen chromosomal duplications, all unlinked to their linkage group of origin, have been identified following X-irradiation. Ten are X-chromosome duplications, of which six are half-translocations on three autosomomal linkage groups and four are free fragments. Five of the half-translocations are homozygous fertile and two are recognizable cytologically as chromosome satellites, both of which show some mitotic instability. The free-X duplications show varying tendencies for loss. Three appear not to overlap in extent previously identified free-X duplications. The fourth carries genes from linkage group V, as well as X. Three duplications of a portion of linkage group II were identified and found to be free and quite stable in hyperploids. Some of the free duplications tend to disjoin from the X chromosome in males. New X-chromosome map data are presented.

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