scholarly journals Preterm Birth Associated With Group B Streptococcus Maternal Colonization Worldwide: Systematic Review and Meta-analyses

2017 ◽  
Vol 65 (suppl_2) ◽  
pp. S133-S142 ◽  
Author(s):  
Fiorella Bianchi-Jassir ◽  
Anna C Seale ◽  
Maya Kohli-Lynch ◽  
Joy E Lawn ◽  
Carol J Baker ◽  
...  
Keyword(s):  
Systematic Review ◽  
Preterm Birth ◽  
Group B Streptococcus ◽  
Group B ◽  
Meta Analyses

scholarly journals Maternal Disease With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses

2017 ◽  
Vol 65 (suppl_2) ◽  
pp. S112-S124 ◽  
Author(s):  
Jennifer Hall ◽  
Nadine Hack Adams ◽  
Linda Bartlett ◽  
Anna C Seale ◽  
Theresa Lamagni ◽  
...  
Keyword(s):  
Systematic Review ◽  
Group B Streptococcus ◽  
Serotype Distribution ◽  
Group B ◽  
Meta Analyses ◽  
Maternal Disease

scholarly journals Stillbirth With Group B Streptococcus Disease Worldwide: Systematic Review and Meta-analyses

2017 ◽  
Vol 65 (suppl_2) ◽  
pp. S125-S132 ◽  
Author(s):  
Anna C Seale ◽  
Hannah Blencowe ◽  
Fiorella Bianchi-Jassir ◽  
Nicholas Embleton ◽  
Quique Bassat ◽  
...  
Keyword(s):  
Systematic Review ◽  
Group B Streptococcus ◽  
Group B ◽  
Meta Analyses

scholarly journals Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China

2020 ◽  
Vol 26 (11) ◽  
pp. 2651-2659
Author(s):  
Yijun Ding ◽  
Yajuan Wang ◽  
Yingfen Hsia ◽  
Neal Russell ◽  
Paul T. Heath
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Group B Streptococcus ◽  
Group B ◽  
Meta Analyses

scholarly journals Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses

2017 ◽  
Vol 65 (suppl_2) ◽  
pp. S100-S111 ◽  
Author(s):  
Neal J Russell ◽  
Anna C Seale ◽  
Megan O’Driscoll ◽  
Catherine O’Sullivan ◽  
Fiorella Bianchi-Jassir ◽  
...  
Keyword(s):  
Systematic Review ◽  
Group B Streptococcus ◽  
Serotype Distribution ◽  
Group B ◽  
Meta Analyses

scholarly journals Relationship between vaginal group B streptococcus colonization in the early stage of pregnancy and preterm birth: a retrospective cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sho Tano ◽  
Takuji Ueno ◽  
Michinori Mayama ◽  
Takuma Yamada ◽  
Takehiko Takeda ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Birth ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Early Stage ◽  
Group B Streptococcus ◽  
Multivariable Logistic Regression Analysis ◽  
Simple Method ◽  
Group B ◽  
Singleton Pregnancies

Abstract Background Although infection and inflammation within the genital tract during pregnancy is considered a major risk factor for spontaneous preterm birth (PTB), there are few studies on association between vaginal microorganisms in the early stage of pregnancy and PTB. The aim of this study was to investigate relationship between vaginal Group B streptococcus (GBS) colonization, a leading cause of infection during pregnancy, in the early stage of pregnancy and PTB. Methods This single-center, retrospective cohort study utilized data from 2009 to 2017 obtained at TOYOTA Memorial Hospital. Women with singleton pregnancies who underwent vaginal culture around 14 weeks of gestation during their routine prenatal check-up were included. Vaginal sampling for Gram staining and culture was performed regardless of symptoms. GBS colonization was defined as positive for GBS latex agglutination assay. Statistical analysis was performed to determine the factors associated with PTB. Results Overall 1079 singleton pregnancies were included. GBS (5.7%) and Candida albicans (5.5%) were the most frequently observed microorganisms. The incidence of PTB (before 34 and before 37 weeks of gestation) were significantly higher in the GBS-positive group than in the GBS-negative group (6.6% vs 0.5%, p = 0.001 and 9.8% vs 4.3%, p = 0.047). Our multivariable logistic regression analysis revealed that GBS colonization was a factor associated with PTB before 34 and before 37 weeks of gestation (Odds ratio [OR] 15.17; 95% confidence interval [CI] 3.73–61.74), and OR 2.42; 95%CI 1.01–5.91, respectively). Conclusions The present study found that vaginal GBS colonization in the early stage of pregnancy was associated with PTB. Our study indicates that patients at a high risk for PTB can be extracted by a simple method using conventional culture method.

Rectovaginal group B streptococcus colonization among pregnant women in Nicaragua: a systematic review and meta-analysis

2019 ◽  
pp. 1-9
Author(s):  
Nadja A. Vielot ◽  
Christian E. Toval-Ruíz ◽  
Rachel Palmieri Weber ◽  
Sylvia Becker-Dreps ◽  
Teresa de Jesús Alemán Rivera
Keyword(s):  
Systematic Review ◽  
Pregnant Women ◽  
Meta Analysis ◽  
Group B Streptococcus ◽  
Group B

scholarly journals Group B Streptococcus and the vaginal microbiome among pregnant women: a systematic review

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11437
Author(s):  
Sungju Lim ◽  
Shilpa Rajagopal ◽  
Ye Ryn Jeong ◽  
Dumebi Nzegwu ◽  
Michelle L. Wright
Keyword(s):  
Systematic Review ◽  
Group B Streptococcus ◽  
Taxonomic Composition ◽  
Vaginal Microbiome ◽  
Large Variability ◽  
Microbiome Analysis ◽  
Genus Level ◽  
Level Data ◽  
Subsequent Birth ◽  
Group B

Background Vaginal microbiome studies frequently report diversity metrics and communities of microbiomes associated with reproductive health outcomes. Reports of Streptococcus agalactiae (also known as Group B Streptococcus or GBS), the leading cause of neonatal infectious morbidity and mortality, are notably lacking from the studies of the vaginal microbiome, despite being a known contributor to preterm birth and other complications. Therefore, the purpose of this systematic review was to explore the frequency of GBS reporting in vaginal microbiome literature pertaining to pregnancy and to examine methodological bias that contributes to differences in species and genus-level microbiome reporting. Lack of identification of GBS via sequencing-based approaches due to methodologic or reporting bias may result incomplete understanding of bacterial composition during pregnancy and subsequent birth outcomes. Methodology A systematic review was conducted following the PRISMA guideline. Three databases (PubMed, CINAHL, and Web of Science) were used to identify papers for review based on the search terms “vaginal microbiome”, “pregnancy”, and “16S rRNA sequencing”. Articles were evaluated for methods of DNA extraction and sequencing, 16S region, taxonomy classification database, number of participants or vaginal specimens, and pregnancy trimester. Results Forty-five research articles reported employing a metagenomic approach or 16S approach for vaginal microbiome analysis during pregnancy that explicitly reported taxonomic composition and were included in this review. Less than 30% of articles reported the presence of GBS (N = 13). No significant differences in methodology were identified between articles that reported versus did not report GBS. However, there was large variability across research methods used for vaginal microbiome analysis and species-level bacterial community reporting. Conclusion Considerable differences in study design and data formatting methods may contribute to underrepresentation of GBS, and other known pathogens, in existing vaginal microbiome literature. Previous studies have identified considerable variation in methodology across vaginal microbiome studies. This study adds to this body of work because in addition to laboratory or statistical methods, how results and data are shared (e.g., only analyzing genus level data or 20 most abundant microbes), may hinder reproducibility and limit our understanding of the influence of less abundant microbes. Sharing detailed methods, analysis code, and raw data may improve reproducibility and ability to more accurately compare microbial communities across studies.

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