scholarly journals Capillary Electrophoresis for Simultaneous Analysis of Heparin, Chondroitin Sulfate and Hyaluronic Acid and its Application in Preparations and Synovial Fluid

2012 ◽  
Vol 50 (5) ◽  
pp. 373-379 ◽  
Author(s):  
X. Liu ◽  
C. Sun ◽  
H. Zang ◽  
W. Wang ◽  
R. Guo ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Hyaluronic Acid ◽  
Synovial Fluid ◽  
Chondroitin Sulfate ◽  
Simultaneous Analysis

Online preconcentration and determination of chondroitin sulfate, dermatan sulfate and hyaluronic acid in biological and cosmetic samples using capillary electrophoresis

2019 ◽  
Vol 42 (17) ◽  
pp. 2867-2874 ◽  
Author(s):  
Kanokporn Chindaphan ◽  
Kanet Wongravee ◽  
Thumnoon Nhujak ◽  
Thasinas Dissayabutra ◽  
Monpichar Srisa‐Art
Keyword(s):  
Capillary Electrophoresis ◽  
Hyaluronic Acid ◽  
Chondroitin Sulfate ◽  
Dermatan Sulfate ◽  
Online Preconcentration

Comparison of the antioxidant effects of synovial fluid from equine metacarpophalangeal joints with those of hyaluronic acid and chondroitin sulfate

2010 ◽  
Vol 71 (4) ◽  
pp. 399-404 ◽  
Author(s):  
Andrea J. Müller ◽  
María E. Letelier ◽  
Marco A. Galleguillos ◽  
Alfredo E. Molina-Berríos ◽  
Héctor H. Adarmes
Keyword(s):  
Hyaluronic Acid ◽  
Synovial Fluid ◽  
Chondroitin Sulfate ◽  
Metacarpophalangeal Joints ◽  
Antioxidant Effects

scholarly journals Oral glucosamine and chondroitin sulfate on synovial fluid biomarkers from osteoarthritic equine joints

2019 ◽  
Vol 49 (9) ◽  
Author(s):  
Juliana Junqueira Moreira ◽  
Joyce Martins Coelho ◽  
Thais Sodré Lima Machado ◽  
Ana Paula Lopes Morais ◽  
Yara Maria Michelacci ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Synovial Fluid ◽  
Chondroitin Sulfate ◽  
Oral Treatment ◽  
Anabolic Effect ◽  
Oral Supplementation ◽  
Systemic Distribution ◽  
End Of Treatment ◽  
Anti Inflammatory

ABSTRACT: Several studies, mainly in vitro, have shown that chondroitin sulfate (CS) and glucosamine (GlcN) do have chondro protective and anti-inflammatory actions. The aim of the present study was to investigate whether oral CS/GlcN supplementation has effects on the CS, hyaluronic acid (HA) and prostaglandin E2 (PGE2) concentrations on synovial fluid of equine osteoarthritic joints. Horses with mild osteoarthritis (OA) in tibiotarsal joint received daily PO doses of CS and GlcN (2.8/3.1 g) for 25 days. Synovial fluid (SF) and urine samples were collected before treatment (day 0), and every 7 days, until day 55 (30 days after the end of treatment). Urinary CS increased upon oral treatment, indicating that this compound was systemically distributed. Concerning the SF, CS concentration increased after the end of the treatment and returning to baseline afterwards, while HA and PGE2 concentrations did not change. Despite the systemic distribution, oral supplementation of CS/GlcNfor 25 days was insufficient as an anti-inflammatory support. However, it is possible to infer that there was an anabolic effect upon cartilage matrix.

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