scholarly journals Functional Heterogeneity in Posterior Parietal Cortex Across Attention and Episodic Memory Retrieval

2012 ◽  
Vol 24 (1) ◽  
pp. 49-66 ◽  
Author(s):  
J. Benjamin Hutchinson ◽  
Melina R. Uncapher ◽  
Kevin S. Weiner ◽  
David W. Bressler ◽  
Michael A. Silver ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Parietal Cortex ◽  
Memory Retrieval ◽  
Posterior Parietal Cortex ◽  
Functional Heterogeneity ◽  
Posterior Parietal

scholarly journals The contribution of the human posterior parietal cortex to episodic memory

2017 ◽  
Vol 18 (3) ◽  
pp. 183-192 ◽  
Author(s):  
Carlo Sestieri ◽  
Gordon L. Shulman ◽  
Maurizio Corbetta
Keyword(s):  
Episodic Memory ◽  
Parietal Cortex ◽  
Posterior Parietal Cortex ◽  
Posterior Parietal

scholarly journals Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Yoonjeong Jeon ◽  
Yun Lim ◽  
Jiwoo Yeom ◽  
Eun-Kyoung Kim
Keyword(s):  
Mental Disorders ◽  
Parietal Cortex ◽  
Metabolic Pathways ◽  
Memory Retrieval ◽  
Posterior Parietal Cortex ◽  
Conditioned Fear ◽  
Fear Memory ◽  
Glutathione Metabolism ◽  
Potential Biomarker ◽  
Posterior Parietal

AbstractFear conditioning and retrieval are suitable models to investigate the biological basis of various mental disorders. Hippocampus and amygdala neurons consolidate conditioned stimulus (CS)-dependent fear memory. Posterior parietal cortex is considered important for the CS-dependent conditioning and retrieval of fear memory. Metabolomic screening among functionally related brain areas provides molecular signatures and biomarkers to improve the treatment of psychopathologies. Herein, we analyzed and compared changes of metabolites in the hippocampus, amygdala, and posterior parietal cortex under the fear retrieval condition. Metabolite profiles of posterior parietal cortex and amygdala were similarly changed after fear memory retrieval. While the retrieval of fear memory perturbed various metabolic pathways, most metabolic pathways that overlapped among the three brain regions had high ranks in the enrichment analysis of posterior parietal cortex. In posterior parietal cortex, the most perturbed pathways were pantothenate and CoA biosynthesis, purine metabolism, glutathione metabolism, and NAD+ dependent signaling. Metabolites of posterior parietal cortex including 4′-phosphopantetheine, xanthine, glutathione, ADP-ribose, ADP-ribose 2′-phosphate, and cyclic ADP-ribose were significantly regulated in these metabolic pathways. These results point to the importance of metabolites of posterior parietal cortex in conditioned fear memory retrieval and may provide potential biomarker candidates for traumatic memory-related mental disorders.

scholarly journals The posterior parietal cortex and subjectively perceived confidence during memory retrieval

2018 ◽  
Vol 25 (8) ◽  
pp. 382-389 ◽  
Author(s):  
Syanah C. Wynn ◽  
Marc P. H. Hendriks ◽  
Sander M. Daselaar ◽  
Roy P. C. Kessels ◽  
Dennis J. L. G. Schutter
Keyword(s):  
Parietal Cortex ◽  
Memory Retrieval ◽  
Posterior Parietal Cortex ◽  
Posterior Parietal

scholarly journals Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory

2021 ◽  
Author(s):  
Yoonjeong Jeon ◽  
Jiwoo Yeom ◽  
Eun-Kyoung Kim
Keyword(s):  
Mental Disorders ◽  
Parietal Cortex ◽  
Metabolic Pathways ◽  
Memory Retrieval ◽  
Posterior Parietal Cortex ◽  
Conditioned Fear ◽  
Fear Memory ◽  
Glutathione Metabolism ◽  
Potential Biomarker ◽  
Posterior Parietal

Abstract Fear conditioning and retrieval are suitable models to investigate the biological basis of various mental disorders. Hippocampus and amygdala neurons consolidate conditioned stimulus (CS)-dependent fear memory. Posterior parietal cortex is considered important for the CS-dependent conditioning and retrieval of fear memory. Metabolomic screening among functionally related brain areas provides molecular signatures and biomarkers to improve the treatment of psychopathologies. Herein, we analyzed and compared changes of metabolites in the hippocampus, amygdala and posterior parietal cortex under the fear retrieval condition. Metabolite profiles of posterior parietal cortex and amygdala were similarly changed after fear memory retrieval. While the retrieval of fear memory perturbed various metabolic pathways, most metabolic pathways that overlapped among the three brain regions had high ranks in the enrichment analysis of posterior parietal cortex. In posterior parietal cortex, the most perturbed pathways were pantothenate and CoA biosynthesis, purine metabolism, glutathione metabolism, and NAD+ dependent signaling. Metabolites of posterior parietal cortex including 4′-phosphopantetheine, xanthine, glutathione, ADP-ribose, ADP-ribose phosphate, and cyclic ADP-ribose were significantly regulated in these metabolic pathways. These results point to the importance of metabolites of posterior parietal cortex in conditioned fear memory retrieval and may provide potential biomarker candidates for traumatic memory–related mental disorders.

scholarly journals Functional Differentiation of Memory Retrieval Network in Macaque Posterior Parietal Cortex

Neuron ◽  
2013 ◽  
Vol 77 (4) ◽  
pp. 787-799 ◽  
Author(s):  
Kentaro Miyamoto ◽  
Takahiro Osada ◽  
Yusuke Adachi ◽  
Teppei Matsui ◽  
Hiroko M. Kimura ◽  
...  
Keyword(s):  
Parietal Cortex ◽  
Memory Retrieval ◽  
Posterior Parietal Cortex ◽  
Functional Differentiation ◽  
Posterior Parietal
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