scholarly journals Layer-specific Production of Nitric Oxide during Cortical Circuit Formation in Postnatal Mouse Brain

2004 ◽  
Vol 15 (3) ◽  
pp. 332-340 ◽  
Author(s):  
T. Imura
Keyword(s):  
Nitric Oxide ◽  
Mouse Brain ◽  
Specific Production ◽  
Cortical Circuit ◽  
Circuit Formation

Developmental shift in bidirectional functions of taurine-sensitive chloride channels during cortical circuit formation in postnatal mouse brain

2004 ◽  
Vol 60 (2) ◽  
pp. 166-175 ◽  
Author(s):  
Mika Yoshida ◽  
Satoshi Fukuda ◽  
Yusuke Tozuka ◽  
Yusei Miyamoto ◽  
Tatsuhiro Hisatsune
Keyword(s):  
Mouse Brain ◽  
Chloride Channels ◽  
Developmental Shift ◽  
Cortical Circuit ◽  
Circuit Formation

scholarly journals Genotoxic and oxidative effect of duloxetine on mouse brain and liver tissues

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Isela Álvarez-González ◽  
Scarlett Camacho-Cantera ◽  
Patricia Gómez-González ◽  
Michael J. Rendón Barrón ◽  
José A. Morales-González ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dna Damage ◽  
Mouse Brain ◽  
Control Level ◽  
Dna Oxidation ◽  
Methyl Methanesulfonate ◽  
Control Group ◽  
Oxidative Potential ◽  
The Brain ◽  
Oxidative Effect

AbstractWe evaluated the duloxetine DNA damaging capacity utilizing the comet assay applied to mouse brain and liver cells, as well as its DNA, lipid, protein, and nitric oxide oxidative potential in the same cells. A kinetic time/dose strategy showed the effect of 2, 20, and 200 mg/kg of the drug administered intraperitoneally once in comparison with a control and a methyl methanesulfonate group. Each parameter was evaluated at 3, 9, 15, and 21 h postadministration in five mice per group, except for the DNA oxidation that was examined only at 9 h postadministration. Results showed a significant DNA damage mainly at 9 h postexposure in both organs. In the brain, with 20 and 200 mg/kg we found 50 and 80% increase over the control group (p ≤ 0.05), in the liver, the increase of 2, 20, and 200 mg/kg of duloxetine was 50, 80, and 135% in comparison with the control level (p ≤ 0.05). DNA, lipid, protein and nitric oxide oxidation increase was also observed in both organs. Our data established the DNA damaging capacity of duloxetine even with a dose from the therapeutic range (2 mg/kg), and suggest that this effect can be related with its oxidative potential.

scholarly journals Characterization of the Subventricular-Thalamo-Cortical Circuit in the NP-C Mouse Brain, and New Insights Regarding Treatment

2019 ◽  
Vol 27 (8) ◽  
pp. 1507-1526 ◽  
Author(s):  
Min Hee Park ◽  
Byung Jo Choi ◽  
Min Seock Jeong ◽  
Ju Youn Lee ◽  
In Kyung Jung ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Cortical Circuit

Neuroprotective Effect of Chuk-Me-Sun-Dan on NMDA- and AMPA-Evoked Nitric Oxide Synthase Activity in Mouse Brain

2005 ◽  
Vol 27 (3) ◽  
pp. 499-514 ◽  
Author(s):  
Byung-Soo Koo ◽  
Eun-Gyu Choi ◽  
Jae-Bok Park ◽  
Chang-Ho Cho ◽  
Kang-Hyun Chung ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Mouse Brain ◽  
Neuroprotective Effect ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

Acetylcholine induces intracellular Ca2+ oscillations and nitric oxide release in mouse brain endothelial cells

Cell Calcium ◽  
2017 ◽  
Vol 66 ◽  
pp. 33-47 ◽  
Author(s):  
Estella Zuccolo ◽  
Dmitry Lim ◽  
Dlzar Ali Kheder ◽  
Angelica Perna ◽  
Paolo Catarsi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Mouse Brain ◽  
Brain Endothelial Cells ◽  
Nitric Oxide Release ◽  
Mouse Brain Endothelial Cells

Poster #128 NITRIC OXIDE SYNTHASE ACTIVITY IS DIFFERENTIALLY ALTERED BETWEEN ACUTE AND SUBCHRONIC PHENCYCLIDINE TREATMENTS IN DISCRETE MOUSE BRAIN REGIONS

2012 ◽  
Vol 136 ◽  
pp. S137-S138
Author(s):  
Graham Lee ◽  
David M. Thomson ◽  
Allan McVie ◽  
Colin J. Suckling ◽  
Brian J. Morris ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Mouse Brain ◽  
Brain Regions ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity
Sign in / Sign up

Export Citation Format

Share Document