scholarly journals Cell signaling pathways associated with a reduction in mammary cancer burden by dietary common bean ( Phaseolus vulgaris L.)

2011 ◽  
Vol 33 (1) ◽  
pp. 226-232 ◽  
Author(s):  
Matthew D. Thompson ◽  
Meghan M. Mensack ◽  
Weiqin Jiang ◽  
Zongjian Zhu ◽  
Matthew R. Lewis ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Cell Signaling ◽  
Common Bean ◽  
Signaling Pathways ◽  
Mammary Cancer ◽  
Phaseolus Vulgaris L ◽  
Cancer Burden ◽  
Cell Signaling Pathways

scholarly journals Cell Signaling Pathways in Mammary Carcinoma Induced in Rats with Low versus High Inherent Aerobic Capacity

2019 ◽  
Vol 20 (6) ◽  
pp. 1506 ◽  
Author(s):  
Tymofiy Lutsiv ◽  
John McGinley ◽  
Elizabeth Neil ◽  
Henry Thompson
Keyword(s):  
Physical Activity ◽  
Fatty Acid ◽  
Cell Signaling ◽  
Signaling Pathways ◽  
Aerobic Capacity ◽  
Mammary Cancer ◽  
Breast Cancer Incidence ◽  
Acid Oxidation ◽  
Inverse Association ◽  
Cell Signaling Pathways

An inverse association exists between physical activity and breast cancer incidence and outcomes. An objective indicator of an individual’s recent physical activity exposure is aerobic capacity. We took advantage of the fact that there is an inherited as well as inducible component of aerobic capacity to show that experimentally induced mammary cancer is inversely related to inherent aerobic capacity (IAC). The objective of this study was to determine whether cell signaling pathways involved in the development of mammary cancer differed in rats with low inherent aerobic capacity (LIAC, n = 55) versus high inherent aerobic capacity (HIAC, n = 57). Cancer burden was 0.21 ± 0.16 g/rat in HIAC versus 1.14 ± 0.45 in LIAC, p < 0.001. Based on protein expression, cancer in LIAC animals was associated with upregulated glucose utilization, and protein and fatty acid synthesis. Signaling in cancers from HIAC rats was associated with energy sensing, fatty acid oxidation and cell cycle arrest. These findings support the thesis that pro-glycolytic, metabolic inflexibility in LIAC favors not only insulin resistance and obesity but also tumor development and growth. This provides an unappreciated framework for understanding how obesity and low aerobic fitness, hallmarks of physical inactivity, are associated with higher cancer risk and poorer prognosis.

scholarly journals Characterization of common bean ( Phaseolus vulgaris L.) germplasm for morphological and seed nutrient traits from Western Himalayas

2021 ◽  
Author(s):  
Sofora Jan ◽  
Irshad Ahmad Rather ◽  
Parvaze Ahmad Sofi ◽  
Mohd Altaf Wani ◽  
Farooq Ahmad Sheikh ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Common Bean ◽  
Western Himalayas ◽  
Phaseolus Vulgaris L ◽  
Nutrient Traits

scholarly journals Common bean ( Phaseolus vulgaris L.) with increased cysteine and methionine concentration

2021 ◽  
Author(s):  
Rosa Cecilia Viscarra‐Torrico ◽  
Aga Pajak ◽  
Alvaro Soler Garzón ◽  
BaiLing Zhang ◽  
Sudhakar Pandurangan ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Common Bean ◽  
Phaseolus Vulgaris L ◽  
Methionine Concentration

Impact of soil moisture on common bean (Phaseolus vulgaris L.) phytochemicals

2021 ◽  
Vol 99 ◽  
pp. 103883
Author(s):  
Mayra Denise Herrera ◽  
Rosalía Reynoso-Camacho ◽  
Valentín Melero-Meraz ◽  
Salvador H. Guzmán-Maldonado ◽  
Jorge A. Acosta-Gallegos
Keyword(s):  
Soil Moisture ◽  
Phaseolus Vulgaris ◽  
Common Bean ◽  
Phaseolus Vulgaris L

scholarly journals Yield and antiyield genes in common bean ( Phaseolus vulgaris L.)

2021 ◽  
Author(s):  
Yarmilla Reinprecht ◽  
Yanzhou Qi ◽  
Fariba Shahmir ◽  
Thomas H. Smith ◽  
Karl Peter Pauls
Keyword(s):  
Phaseolus Vulgaris ◽  
Common Bean ◽  
Phaseolus Vulgaris L
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