scholarly journals PLASTICITY IN THE HUMAN NERVOUS SYSTEM. INVESTIGATIONS WITH TRANSCRANIAL MAGNETIC STIMULATION

Brain ◽  
2004 ◽  
Vol 127 (5) ◽  
pp. 1212-1213 ◽  
Author(s):  
K. R. Mills
2007 ◽  
Vol 87 (6) ◽  
pp. 719-736 ◽  
Author(s):  
Andrew J Butler ◽  
Steven L Wolf

The plasticity of the brain is an increasingly important topic for physical therapists interested in childhood development, learning, and repair following injury. The study of plasticity directly in the human nervous system presents numerous challenges, such as the ability to assess neuronal function in vivo because of physical impediments, such as the skull, skin, and dura. Transcranial magnetic stimulation (TMS), however, has become a suitable, noninvasive, and painless technique that can be applied to detect changes in cortical excitability as an indicator of neurological changes. Furthermore, repetitive trains of TMS themselves can induce plasticity. This article discusses the use of TMS to investigate and manipulate plasticity in the human nervous system.


2017 ◽  
Vol 2017 ◽  
pp. 1-16 ◽  
Author(s):  
Mengchu Cui ◽  
Hongfei Ge ◽  
Hengli Zhao ◽  
Yongjie Zou ◽  
Yujie Chen ◽  
...  

Localized magnetic fields (MFs) could easily penetrate the scalp, skull, and meninges, thus inducing an electrical current in both the central and peripheral nervous systems, which is primarily used in transcranial magnetic stimulation (TMS) for inducing specific effects on different regions or cells that play roles in various brain activities. Studies of repetitive transcranial magnetic stimulation (rTMS) have led to novel attractive therapeutic approaches. Neural stem cells (NSCs) in adult human brain are able to self-renew and possess multidifferential ability to maintain homeostasis and repair damage after acute central nervous system. In the present review, we summarized the electrical activity of NSCs and the fundamental mechanism of electromagnetic fields and their effects on regulating NSC proliferation, differentiation, migration, and maturation. Although it was authorized for the rTMS use in resistant depression patients by US FDA, there are still unveiling mechanism and limitations for rTMS in clinical applications of acute central nervous system injury, especially on NSC regulation as a rehabilitation strategy. More in-depth studies should be performed to provide detailed parameters and mechanisms of rTMS in further studies, making it a powerful tool to treat people who are surviving with acute central nervous system injuries.


2017 ◽  
Vol 19 (3) ◽  
pp. 49-55
Author(s):  
Igor V Litvinenko ◽  
Anton A Yurin ◽  
Daria N Frunza ◽  
Tatyana V Bodrova

Magnetic stimulation is a noninvasive technique that allows you to directly stimulate the neurons of the cerebral cortex. Currently, transcranial magnetic stimulation is used as informative diagnostic and effective therapeutic techniques for the treatment of diseases and injuries of the nervous system. The article discusses the indications, contraindications and the recommended protocols for the use of transcranial magnetic stimulation in certain diseases and consequences of traumas of the nervous system (bibliography: 37 refs).


Author(s):  
John Rothwell ◽  
Ricci Hannah

Transcranial magnetic stimulation (TMS) can be viewed as interacting with voluntary movement in two ways: it can used to probe the excitability of central nervous system (CNS) pathways before, during, and after a movement; alternatively, it can be used to interfere with movement and give information about the role of different cortical areas in different aspects of a task. This chapter concentrates on the role of single and paired pulse TMS methods that have been covered in detail in previous chapters. Long lasting effects of repetitive TMS (rTMS) are described in later chapters. Almost all of the TMS measures described in previous chapters differ in subjects at rest and during tonic voluntary activity.


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