scholarly journals EEG BURST SUPPRESSION WITH PROPOFOL DURING CARDIOPULMONARY BYPASS IN CHILDREN: A STUDY OF THE HAEMODYNAMIC, METABOLIC AND ENDOCRINE EFFECTS

1992 ◽  
Vol 69 (4) ◽  
pp. 356-362 ◽  
Author(s):  
G.J.A. LAYCOCK ◽  
J.M. MITCHELL ◽  
R.D. PATON ◽  
S.F.O'B. DONAGHEY ◽  
R.W. LOGAN ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Endocrine Effects

Cerebral Physiologic Effects of Burst Suppression Doses of Propofol During Nonpulsatile Cardiopulmonary Bypass

1995 ◽  
Vol 81 (3) ◽  
pp. 452-457 ◽  
Author(s):  
Mark F. Newman ◽  
John M. Murkin ◽  
Gary Roach ◽  
Narda D. Croughwell ◽  
William D. White ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression

A PRELIMINARY REPORT ON THE EFFECTS OF BURST SUPPRESSION DOSES OF PROPOFOL ON CEREBRAL PHYSIOLOGY DURING NONPULSATILE CARDIOPULMONARY BYPASS

1994 ◽  
Vol 81 (SUPPLEMENT) ◽  
pp. A159
Author(s):  
M. Newman ◽  
J. Murkin ◽  
G. Roach ◽  
N. Croughwell ◽  
D. Kramer ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Preliminary Report ◽  
Burst Suppression ◽  
Cerebral Physiology

Arterial isoflurane concentration and EEG burst suppression during cardiopulmonary bypass

1986 ◽  
Vol 40 (3) ◽  
pp. 304-313 ◽  
Author(s):  
Christopher W Loomis ◽  
Donald Brunet ◽  
Brian Milne ◽  
Frank W Cervenko ◽  
Graeme D Johnson
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Isoflurane Concentration

scholarly journals Plasma propofol concentration and EEG burst suppression ratio during normothermic cardiopulmonary bypass †

2003 ◽  
Vol 90 (2) ◽  
pp. 122-126 ◽  
Author(s):  
K. Yoshitani ◽  
M. Kawaguchi ◽  
M. Takahashi ◽  
K. Kitaguchi ◽  
H. Furuya
Keyword(s):  
Cardiopulmonary Bypass ◽  
Suppression Ratio ◽  
Burst Suppression

scholarly journals Electroencephalogram dynamics during general anesthesia predict the later incidence and duration of burst-suppression during cardiopulmonary bypass

2019 ◽  
Vol 130 (1) ◽  
pp. 55-60 ◽  
Author(s):  
George S. Plummer ◽  
Reine Ibala ◽  
Eunice Hahm ◽  
Jingzhi An ◽  
Jacob Gitlin ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
General Anesthesia ◽  
Burst Suppression

Arterial Isoflurane Concentration and EEG Burst Suppression During Cardiopulmonary Bypass

1987 ◽  
Vol XXXI (3) ◽  
pp. 154
Author(s):  
C. W. LOOMIS ◽  
D. BRUNET ◽  
B. MILNE ◽  
F. W. CERVENKO ◽  
G. D. JOHNSON
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Isoflurane Concentration

Dose-Related Changes in Plasma Propofol Concentration and Burst Suppression Ratio on Electroencephalography during Normothermic Cardiopulmonary Bypass

2002 ◽  
Vol 96 (Sup 2) ◽  
pp. A239
Author(s):  
Kenji Yoshitani ◽  
Masahiko Kawaguchi ◽  
Masahiro Takahashi ◽  
Katsuyasu Kitaguchi ◽  
Hitoshi Furuya
Keyword(s):  
Cardiopulmonary Bypass ◽  
Suppression Ratio ◽  
Burst Suppression

scholarly journals Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium

2020 ◽  
Vol 133 (2) ◽  
pp. 280-292 ◽  
Author(s):  
Juan C. Pedemonte ◽  
George S. Plummer ◽  
Shubham Chamadia ◽  
Joseph J. Locascio ◽  
Eunice Hahm ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiopulmonary Bypass ◽  
Physical Function ◽  
Cognitive Assessment ◽  
Odds Ratio ◽  
Postoperative Delirium ◽  
Burst Suppression ◽  
Alpha Power ◽  
Multivariable Model ◽  
Univariate Analyses

Background Intraoperative burst-suppression is associated with postoperative delirium. Whether this association is causal remains unclear. Therefore, the authors investigated whether burst-suppression during cardiopulmonary bypass (CPB) mediates the effects of known delirium risk factors on postoperative delirium. Methods This was a retrospective cohort observational substudy of the Minimizing ICU [intensive care unit] Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS) trial. The authors analyzed data from patients more than 60 yr old undergoing cardiac surgery (n = 159). Univariate and multivariable regression analyses were performed to assess for associations and enable causal inference. Delirium risk factors were evaluated using the abbreviated Montreal Cognitive Assessment and Patient-Reported Outcomes Measurement Information System questionnaires for applied cognition, physical function, global health, sleep, and pain. The authors also analyzed electroencephalogram data (n = 141). Results The incidence of delirium in patients with CPB burst-suppression was 25% (15 of 60) compared with 6% (5 of 81) in patients without CPB burst-suppression. In univariate analyses, age (odds ratio, 1.08 [95% CI, 1.03 to 1.14]; P = 0.002), lowest CPB temperature (odds ratio, 0.79 [0.66 to 0.94]; P = 0.010), alpha power (odds ratio, 0.65 [0.54 to 0.80]; P < 0.001), and physical function (odds ratio, 0.95 [0.91 to 0.98]; P = 0.007) were associated with CPB burst-suppression. In separate univariate analyses, age (odds ratio, 1.09 [1.02 to 1.16]; P = 0.009), abbreviated Montreal Cognitive Assessment (odds ratio, 0.80 [0.66 to 0.97]; P = 0.024), alpha power (odds ratio, 0.75 [0.59 to 0.96]; P = 0.025), and CPB burst-suppression (odds ratio, 3.79 [1.5 to 9.6]; P = 0.005) were associated with delirium. However, only physical function (odds ratio, 0.96 [0.91 to 0.99]; P = 0.044), lowest CPB temperature (odds ratio, 0.73 [0.58 to 0.88]; P = 0.003), and electroencephalogram alpha power (odds ratio, 0.61 [0.47 to 0.76]; P < 0.001) were retained as predictors in the burst-suppression multivariable model. Burst-suppression (odds ratio, 4.1 [1.5 to 13.7]; P = 0.012) and age (odds ratio, 1.07 [0.99 to 1.15]; P = 0.090) were retained as predictors in the delirium multivariable model. Delirium was associated with decreased electroencephalogram power from 6.8 to 24.4 Hertz. Conclusions The inference from the present study is that CPB burst-suppression mediates the effects of physical function, lowest CPB temperature, and electroencephalogram alpha power on delirium. Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New

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