Arterial isoflurane concentration and EEG burst suppression during cardiopulmonary bypass

1986 ◽  
Vol 40 (3) ◽  
pp. 304-313 ◽  
Author(s):  
Christopher W Loomis ◽  
Donald Brunet ◽  
Brian Milne ◽  
Frank W Cervenko ◽  
Graeme D Johnson
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Isoflurane Concentration

Arterial Isoflurane Concentration and EEG Burst Suppression During Cardiopulmonary Bypass

1987 ◽  
Vol XXXI (3) ◽  
pp. 154
Author(s):  
C. W. LOOMIS ◽  
D. BRUNET ◽  
B. MILNE ◽  
F. W. CERVENKO ◽  
G. D. JOHNSON
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Isoflurane Concentration

Cerebral Physiologic Effects of Burst Suppression Doses of Propofol During Nonpulsatile Cardiopulmonary Bypass

1995 ◽  
Vol 81 (3) ◽  
pp. 452-457 ◽  
Author(s):  
Mark F. Newman ◽  
John M. Murkin ◽  
Gary Roach ◽  
Narda D. Croughwell ◽  
William D. White ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression

The depth of anaesthesia associated with the administration of isoflurane 2.5% during cardiopulmonary bypass

Perfusion ◽  
2019 ◽  
Vol 34 (5) ◽  
pp. 392-398 ◽  
Author(s):  
R Peter Alston ◽  
Michael Connelly ◽  
Christopher MacKenzie ◽  
George Just ◽  
Natalie Homer
Keyword(s):  
Cardiopulmonary Bypass ◽  
Bispectral Index ◽  
Venous Blood ◽  
Index Score ◽  
Mixed Venous Blood ◽  
Depth Of Anaesthesia ◽  
Isoflurane Concentration ◽  
Time Points ◽  
Arterial Blood ◽  
Mixed Venous

Background:Administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass results in no patient movement. However, doing so may result in an excessive depth of anaesthesia particularly, when hypothermia is induced. Bispectral index and arterial blood and oxygenator exhaust concentrations of volatile anaesthetics should be related to depth of anaesthesia. The primary aim of this study was to measure the depth of anaesthesia using bispectral index, resulting from administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass, and secondary aims were to examine the relationships between blood and oxygenator exhaust isoflurane concentrations and bispectral index.Methods:Arterial and mixed-venous blood samples were aspirated at three time points during cardiopulmonary bypass and measured for isoflurane concentration using mass spectrometry. Simultaneously, oxygenator exhaust isoflurane concentration, nasopharyngeal temperature and bispectral index were recorded.Results:When averaged across the three time points, all patients had a bispectral index score below 40 (binomial test, p < 0.001). There were no significant correlations between bispectral index score and arterial or mixed-venous blood isoflurane concentrations (r = –0.082, p = 0.715; r = –0.036, p = 0.874) and oxygenator exhaust gas concentration of isoflurane (r = –0.369, p = 0.091).Conclusion:When 2.5% isoflurane was administered into the sweep gas supply to the oxygenator during cardiopulmonary bypass, all patients experienced a bispectral index score less than 40 and no significant relationship was found between either arterial or mixed-venous blood or oxygenator exhaust concentrations of isoflurane and bispectral index.

A PRELIMINARY REPORT ON THE EFFECTS OF BURST SUPPRESSION DOSES OF PROPOFOL ON CEREBRAL PHYSIOLOGY DURING NONPULSATILE CARDIOPULMONARY BYPASS

1994 ◽  
Vol 81 (SUPPLEMENT) ◽  
pp. A159
Author(s):  
M. Newman ◽  
J. Murkin ◽  
G. Roach ◽  
N. Croughwell ◽  
D. Kramer ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Preliminary Report ◽  
Burst Suppression ◽  
Cerebral Physiology

scholarly journals Plasma propofol concentration and EEG burst suppression ratio during normothermic cardiopulmonary bypass †

2003 ◽  
Vol 90 (2) ◽  
pp. 122-126 ◽  
Author(s):  
K. Yoshitani ◽  
M. Kawaguchi ◽  
M. Takahashi ◽  
K. Kitaguchi ◽  
H. Furuya
Keyword(s):  
Cardiopulmonary Bypass ◽  
Suppression Ratio ◽  
Burst Suppression

scholarly journals Electroencephalogram dynamics during general anesthesia predict the later incidence and duration of burst-suppression during cardiopulmonary bypass

2019 ◽  
Vol 130 (1) ◽  
pp. 55-60 ◽  
Author(s):  
George S. Plummer ◽  
Reine Ibala ◽  
Eunice Hahm ◽  
Jingzhi An ◽  
Jacob Gitlin ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
General Anesthesia ◽  
Burst Suppression

scholarly journals EEG BURST SUPPRESSION WITH PROPOFOL DURING CARDIOPULMONARY BYPASS IN CHILDREN: A STUDY OF THE HAEMODYNAMIC, METABOLIC AND ENDOCRINE EFFECTS

1992 ◽  
Vol 69 (4) ◽  
pp. 356-362 ◽  
Author(s):  
G.J.A. LAYCOCK ◽  
J.M. MITCHELL ◽  
R.D. PATON ◽  
S.F.O'B. DONAGHEY ◽  
R.W. LOGAN ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Burst Suppression ◽  
Endocrine Effects
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