scholarly journals INSRIRED OXYGEN AND OXYGEN TRANSFER DURING ARTIFICIAL VENTILATION FOR RESPIRATORY FAILURE

1983 ◽  
Vol 55 (1) ◽  
pp. 3-13 ◽  
Author(s):  
G.B. DRUMMOND ◽  
N.S. ZHONG
1977 ◽  
Vol 5 (4) ◽  
pp. 372-377 ◽  
Author(s):  
O. F. James ◽  
R. M. Mills ◽  
K. Murree Allen

One thousand, six hundred and sixteen patients with acute respiratory failure were managed in a regional respiratory unit. The patients are classified according to cause, the need for artificial ventilation and results.


2021 ◽  
Author(s):  
Karolina Dolezalova ◽  
Cabelova Tamara ◽  
Tomas Hecht ◽  
Pavel Heinige

We present an otherwise healthy, fully immunized 12-year-old girl who was transferred intubated and ventilated to our Paediatric Intensive Care Unit with fever, cough, and acute respiratory failure. The epidemiologic history was positive for COVID-19, and, furthermore, she tested PCR positive resulting from a nasopharyngeal swab. CT of the thorax revealed bilateral consolidation with the tree-in-bud signs. Her condition required artificial ventilation support for 13 days. Remdesivir, pronation, high dose Ascorbic acid with Thiamine, and combined antimicrobial therapy were successfully used. Our patient made a full clinical recovery. The case demonstrates that even though critical course of COVID-19 infection in children is scarce, it might occur. We hereby would like to share our experience with the medical community.


2016 ◽  
Vol 70 (2) ◽  
Author(s):  
Muhammed Kurt ◽  
Udo Boeken ◽  
Jens Litmathe ◽  
Peter Feindt ◽  
Emmeran Gams

Background: Due to an increasing incidence of respiratory failure after cardiac surgery we wanted to study whether nasal continuous positive airway pressure (NCPAP) may improve pulmonary oxygen transfer and may avoid reintubation after coronary operations. Additionally, we compared this protocol to non-invasive positive pressure ventilation (NPPV). Methods: For a period of 2 years we analyzed all patients that were extubated within 12 hours after coronary surgery, and in whom oxygen transfer (PaO2/FIO2) deteriorated without hypercapnia so that all these patients met predefined criteria for reintubation: group A=immediate reintubation (n=88), group B=NCPAP-treatment (n=173), group C=NPPV(n=18). Results: 25,4% of group B- and 22,2% of group C-patients were also intubated after a period of NCPAP or NPPV. All other patients of groups B and C could be weaned from these devices (B = 34.3 ± 5.9 hours; C = 26.4 ± 4.4 h; p<0.05) and were well oxygenated by face mask at ambient pressure (Ratio PaO2/FIO2: B, 138 ± 13; C, 140 ± 13). In group A we found a higher mortality (7.95%) compared to group B (4.04%) and group C (5.55%). NCPAP-patients suffered more frequently from an impaired sternal wound healing (A = 4.5%, B = 8.6%; p<0.05). Conclusions: We conclude that reintubation after cardiac operations should be avoided since NCPAP and NPPV are safe and effective to improve arterial oxygenation in most patients with non hypercapnic respiratory failure.


2000 ◽  
Vol 80 (7) ◽  
pp. 662-670 ◽  
Author(s):  
Wai Pong Wong

Abstract Background and Purpose. The main indications for physical therapy for patients in intensive care units (ICUs) are excessive pulmonary secretions or atelectasis. Timely physical therapy interventions may improve gas exchange and reverse pathological progression, thereby curtailing or avoiding artificial ventilation. The purpose of this case report is to illustrate 24-hour availability of physical therapy for a patient with acute respiratory failure. Case Description. The patient was a 66-year-old man who was admitted to an ICU for acute respiratory failure. Intensive physical therapy, based on Dean's physiologic treatment hierarchy for patients with impaired oxygen transport, consisted of upright body positioning, mobilization and exercise, and active cycles of breathing techniques every 2 hours for the first 12 hours he was in the ICU. Outcomes. In total, the patient received 11 physical therapy sessions over his 48-hour stay in the ICU (6 sessions on day 1 and 5 sessions on day 2). Arterial oxygenation improved markedly with radiographic resolution of infiltrates, and planned endotracheal intubation and mechanical ventilation were avoided. Discussion. This patient with acute respiratory failure received physical therapy in a timely manner afforded by 24-hour access to physical therapy. The intensive physical therapy might be more cost-effective than if the patient had been managed with intubation and mechanical ventilation. Patients in ICUs who have excessive pulmonary secretions or atelectasis may benefit from access to physical therapy 24 hours a day.


The Lancet ◽  
1976 ◽  
Vol 307 (7966) ◽  
pp. 974 ◽  
Author(s):  
J. Labrousse ◽  
A. Tenaillon ◽  
P. Massabie ◽  
G. Simonneau ◽  
J. Lissac

2021 ◽  
Vol 11 (1) ◽  
pp. 3-9
Author(s):  
Karolina Dolezalova ◽  
Cabelova Tamara ◽  
Tomas Hecht ◽  
Pavel Heinige

The authors present a case report of an otherwise healthy, fully immunized 12-year-old girl who had a critical course of COVID-19 infection with acute respiratory failure. The epidemiologic history was positive for COVID-19, and she tested PCR positive resulting from a nasopharyngeal swab. She was presented with fever and cough to a regional pediatric department, and she was immediately intubated and transferred to a pediatric ICU in a University Hospital. CT of the thorax revealed bilateral consolidation with the tree-in-bud signs. Her condition required artificial ventilation support for 13 days. Remdesivir, pronation, high dose Ascorbic acid with Thiamine, and combined antimicrobial therapy were successfully used. The patient made a full clinical recovery. This case report is unique because of a very scarce critical course of COVID-19 infection in children. It demonstrates the successful use of a combined therapeutic approach with artificial ventilation, pronation, Remdesivir, and combined antimicrobial therapy. Clinical symptoms, laboratory results, imaging methods, and therapeutic attitude are mentioned to share our experience with the medical community.


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