Comprehensive review of the identification of essential genes using computational methods: focusing on feature implementation and assessment

2018 ◽  
Author(s):  
Chuan Dong ◽  
Yan-Ting Jin ◽  
Hong-Li Hua ◽  
Qing-Feng Wen ◽  
Sen Luo ◽  
...  
Keyword(s):  
Computational Methods ◽  
Essential Genes ◽  
Comprehensive Review

Recent Advances of Computational Methods for Identifying Bacteriophage Virion Proteins

2020 ◽  
Vol 27 (4) ◽  
pp. 259-264 ◽  
Author(s):  
Wei Chen ◽  
Fulei Nie ◽  
Hui Ding
Keyword(s):  
Experimental Method ◽  
Computational Methods ◽  
Biological Processes ◽  
Future Perspectives ◽  
Accurate Identification ◽  
Independent Dataset ◽  
Computational Approaches ◽  
Comprehensive Review ◽  
The Past ◽  
Mechanism Of Interaction

Phage Virion Proteins (PVP) are essential materials of bacteriophage, which participate in a series of biological processes. Accurate identification of phage virion proteins is helpful to understand the mechanism of interaction between the phage and its host bacteria. Since experimental method is labor intensive and time-consuming, in the past few years, many computational approaches have been proposed to identify phage virion proteins. In order to facilitate researchers to select appropriate methods, it is necessary to give a comprehensive review and comparison on existing computational methods on identifying phage virion proteins. In this review, we summarized the existing computational methods for identifying phage virion proteins and also assessed their performances on an independent dataset. Finally, challenges and future perspectives for identifying phage virion proteins were presented. Taken together, we hope that this review could provide clues to researches on the study of phage virion proteins.

Computational Methods for the Prediction of Microbial Essential Genes

2014 ◽  
Vol 9 (2) ◽  
pp. 89-101 ◽  
Author(s):  
Yao Lu ◽  
Jingyuan Deng ◽  
Matthew Carson ◽  
Hui Lu ◽  
Long Lu
Keyword(s):  
Computational Methods ◽  
Essential Genes
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