scholarly journals A Comprehensive Review of Computational Methods for Automatic Prediction of Schizophrenia With Insight Into Indigenous Populations

2019 ◽  
Vol 10 ◽  
Author(s):  
Randall Ratana ◽  
Hamid Sharifzadeh ◽  
Jamuna Krishnan ◽  
Shaoning Pang
Keyword(s):  
Computational Methods ◽  
Indigenous Populations ◽  
Comprehensive Review ◽  
Insight Into

Computational Approaches to Predict the Non-canonical DNAs

2019 ◽  
Vol 14 (6) ◽  
pp. 470-479 ◽  
Author(s):  
Nazia Parveen ◽  
Amen Shamim ◽  
Seunghee Cho ◽  
Kyeong Kyu Kim
Keyword(s):  
Computational Methods ◽  
Genetic Instability ◽  
Computational Prediction ◽  
Structure And Function ◽  
Sequence Motifs ◽  
Computational Approaches ◽  
Functional Roles ◽  
And Function ◽  
Genetic Events ◽  
Insight Into

Background: Although most nucleotides in the genome form canonical double-stranded B-DNA, many repeated sequences transiently present as non-canonical conformations (non-B DNA) such as triplexes, quadruplexes, Z-DNA, cruciforms, and slipped/hairpins. Those noncanonical DNAs (ncDNAs) are not only associated with many genetic events such as replication, transcription, and recombination, but are also related to the genetic instability that results in the predisposition to disease. Due to the crucial roles of ncDNAs in cellular and genetic functions, various computational methods have been implemented to predict sequence motifs that generate ncDNA. Objective: Here, we review strategies for the identification of ncDNA motifs across the whole genome, which is necessary for further understanding and investigation of the structure and function of ncDNAs. Conclusion: There is a great demand for computational prediction of non-canonical DNAs that play key functional roles in gene expression and genome biology. In this study, we review the currently available computational methods for predicting the non-canonical DNAs in the genome. Current studies not only provide an insight into the computational methods for predicting the secondary structures of DNA but also increase our understanding of the roles of non-canonical DNA in the genome.

The Application of the Blockchain Technology in Voting Systems

2021 ◽  
Vol 54 (3) ◽  
pp. 1-28
Author(s):  
Jun Huang ◽  
Debiao He ◽  
Mohammad S. Obaidat ◽  
Pandi Vijayakumar ◽  
Min Luo ◽  
...  
Keyword(s):  
Research Agenda ◽  
Future Research ◽  
Voting Systems ◽  
Comprehensive Review ◽  
Formal Expression ◽  
Future Research Agenda ◽  
Blockchain Technology ◽  
Peer Network ◽  
Peer To Peer Network ◽  
Insight Into

Voting is a formal expression of opinion or choice, either positive or negative, made by an individual or a group of individuals. However, conventional voting systems tend to be centralized, which are known to suffer from security and efficiency limitations. Hence, there has been a trend of moving to decentralized voting systems, such as those based on blockchain. The latter is a decentralized digital ledger in a peer-to-peer network, where a copy of the append-only ledger of digitally signed and encrypted transactions is maintained by each participant. Therefore, in this article, we perform a comprehensive review of blockchain-based voting systems and classify them based on a number of features (e.g., the types of blockchain used, the consensus approaches used, and the scale of participants). By systematically analyzing and comparing the different blockchain-based voting systems, we also identify a number of limitations and research opportunities. Hopefully, this survey will provide an in-depth insight into the potential utility of blockchain in voting systems and device future research agenda.

scholarly journals У каждого своя Сибирь. Два женских рассказа о депортации калмыков

2020 ◽  
Vol 12 (4) ◽  
pp. 778-800
Author(s):  
Elza-Bair M. Guchinova ◽  
Keyword(s):  
High School ◽  
Textual Analysis ◽  
Adaptation Strategies ◽  
The Body ◽  
Indigenous Populations ◽  
Young Generation ◽  
Inner Life ◽  
Life Choices ◽  
History Of ◽  
Insight Into

Introduction. The proposed publication consists of an introduction, texts of two biographical interviews and comments thereon. Both the conversations took place in Elista (2004, 2017) as part of the research project ‘Everyone Has One’s Own Siberia’ dedicated to the important period in the history of Kalmykia though not yet sufficiently explored by anthropologists and sociologists — the deportation of Kalmyks to Siberia (1943–1956) and related memories. Goals. The project seeks to show the daily survival practices of Kalmyks in Siberia. In the spontaneous biographical interviews focusing on the years of Kalmyk deportation, not only the facts cited are important — of which we would otherwise stay unaware but from the oral narratives — but also the introduced stories of inner life: feelings and thoughts of growing girls. Methods. The paper involves the use of textual analysis and the method of text deconstruction. Results. The transcribed texts show survival and adaptation strategies employed by the young generation of ‘special settlers’ in places of forced residence. For many Kalmyks of that generation, high school was a ‘glass ceiling’, a limitation in life choices. In the narrative of R. Ts. Azydova, we face a today unthinkable social package for KUTV students with children — this illustrates how the korenization policy for indigenous populations in the USSR worked, and provides insight into daily practices of pre-war Elista. The story of T. S. Kachanova especially clearly manifests the ‘language of trauma’, first of all, through the memory of the body, vocabulary of death and displays of laughter. The texts of the interviews shall be interesting to all researchers of Kalmyk deportation and the memory of that period.

APATITIC NANOPOWDERS AND COATINGS: A COMPREHENSIVE REVIEW

2021 ◽  
Author(s):  
RAVINDER PAL SINGH ◽  
UMA BATRA
Keyword(s):  
Sol Gel ◽  
Dip Coating ◽  
Clinical Applications ◽  
Hard Tissue ◽  
Preparation Methods ◽  
Comprehensive Review ◽  
Metallic Substrates ◽  
Surface Modification Techniques ◽  
Dental Applications ◽  
Insight Into

The use of artificial biomaterials has been acclaiming potential therapeutic scope in diverse clinical applications. This review started with the description of the basics of biomaterials, and desirable properties, which are the prerequisites to understand biomaterials. The orthopedic biomaterials, their classification and the importance of calcium phosphate (CaP) materials for hard-tissue applications were utterly discussed. Furthermore, among the various CaP biominerals, the importance of hydroxyapatite (HAP) and its synthesis techniques was comprehensively reviewed. The sol–gel route for the synthesis of HAP nanoparticles and deposition of coatings were systematically studied. Among the metallic substrates, Ti6Al4V alloy remained the focus of this study. Moreover, several film pre-preparation methods were also given due importance. The importance of other surface modification techniques, especially in the context of Ti6Al4V substrates, was also discussed. Among several coating techniques to deposit CaP coatings, special attention was paid to the spin and dip coating techniques. In addition to monolithic HAP coatings, reinforced and antimicrobial HAP coatings were also reviewed from broad perspectives. Therefore, this review provides an in-depth insight into the preparation and properties of apatitic nanoparticles and their coatings for orthopedic and dental applications.

Corporate Sustainability

2021 ◽  
pp. 26-43
Author(s):  
Iwona Bąk ◽  
Katarzyna Cheba
Keyword(s):  
Qualitative Research ◽  
Literature Review ◽  
Corporate Sustainability ◽  
Business Organizations ◽  
Research Directions ◽  
Comprehensive Review ◽  
Research Areas ◽  
Quantitative Analyses ◽  
Insight Into ◽  
The Web

This research provides a comprehensive review of corporate sustainability literature in various application areas. The chapter also highlights the gaps in clearly explaining the scope for it extending and incorporating the term of corporate sustainability into other research areas. The main advantage of this study is that it provides an insight into the state of the art of corporate sustainability in various application areas and future development and research directions. In addition to the literature review in this area, the chapter also presents numerous examples of the understanding of corporate sustainability by various business organizations. The chapter analyses nearly 200 different publications in this field available in the Web of Science database. In addition to quantitative analyses, in-depth qualitative research was also carried out.

scholarly journals Role of Computational Methods in Going beyond X-ray Crystallography to Explore Protein Structure and Dynamics

2018 ◽  
Vol 19 (11) ◽  
pp. 3401 ◽  
Author(s):  
Ashutosh Srivastava ◽  
Tetsuro Nagai ◽  
Arpita Srivastava ◽  
Osamu Miyashita ◽  
Florence Tama
Keyword(s):  
Protein Dynamics ◽  
Computational Methods ◽  
Protein Structures ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
X Ray ◽  
X Ray Crystallography ◽  
Insight Into

Protein structural biology came a long way since the determination of the first three-dimensional structure of myoglobin about six decades ago. Across this period, X-ray crystallography was the most important experimental method for gaining atomic-resolution insight into protein structures. However, as the role of dynamics gained importance in the function of proteins, the limitations of X-ray crystallography in not being able to capture dynamics came to the forefront. Computational methods proved to be immensely successful in understanding protein dynamics in solution, and they continue to improve in terms of both the scale and the types of systems that can be studied. In this review, we briefly discuss the limitations of X-ray crystallography in studying protein dynamics, and then provide an overview of different computational methods that are instrumental in understanding the dynamics of proteins and biomacromolecular complexes.

Expansion Joint Design, Manufacture and Testing for Large Capacity Steam Turbines

2014 ◽  
Vol 592-594 ◽  
pp. 1539-1543
Author(s):  
C.S. Pargaonkar ◽  
Maneesh Batrani
Keyword(s):  
Steam Turbine ◽  
Computational Methods ◽  
Steam Turbines ◽  
Expansion Joint ◽  
Large Capacity ◽  
Expansion Joints ◽  
Joint Design ◽  
Large Size ◽  
Limiting Values ◽  
Insight Into

The rapidly growing trend for higher capacity steam turbines with large steam flows demand the use of long lengths and large size pipes. Thermal expansions of up-to 50mm and pipe diameters up-to 2600mm are required to be dealt with calling for the use of Expansion Joints to control the stresses in both the pipes as well as the end equipment. The bellows in the Expansion Joints used for the steam turbine application are stretched to their limiting values of the stresses in order to make them as flexible as possible with the aim of limiting the pipe and end equipment operational stresses. Three fundamental types of loading are presented to provide insight into the way bellows convolutions are stressed during operation. The optimization of the bellows profile geometry is discussed briefly. A comparison of the resulsts obtainied by proven computational methods as well as by using international EJMA standard is made to highlight the safety built in the well established methods used.

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