Molecular hybridization based on (–)-epigallocatechin gallate as a new class of anti-glycation agents
Keyword(s):
Abstract (–)-Epigallocatechin gallate (EGCG) and olivetol hybrid molecules 1–4 were conveniently synthesized using dielectric barrier discharge (DBD) plasma irradiation. The structures of these unprecedented hybrid molecules were determined by interpretation of spectroscopic data. The unusual hybrid 1 showed improved anti-glycation potency toward the advanced formation of glycation end products (AGEs) than the original EGCG and olivetol. The novel hybrid 1 is an interesting new class of anti-glycation candidate that requires further investigation.
2021 ◽
Vol 1912
(1)
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pp. 012008
Keyword(s):
2019 ◽
Vol 37
(2)
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pp. 369-377
2018 ◽
Vol 643
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pp. 32-41
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2019 ◽
Vol 36
(2)
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pp. 157-173