scholarly journals The Impact of Different CD4 Cell-Count Monitoring and Switching Strategies on Mortality in HIV-Infected African Adults on Antiretroviral Therapy: An Application of Dynamic Marginal Structural Models

2015 ◽  
Vol 182 (7) ◽  
pp. 633-643 ◽  
Author(s):  
Deborah Ford ◽  
James M. Robins ◽  
Maya L. Petersen ◽  
Diana M. Gibb ◽  
Charles F. Gilks ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Structural Models ◽  
Marginal Structural Models ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
The Impact ◽  
Switching Strategies

The Impact of Episodic CD4 Cell Count-Guided Antiretroviral Therapy on Quality of Life

2008 ◽  
Vol 47 (2) ◽  
pp. 185-193 ◽  
Author(s):  
William J Burman ◽  
Birgit Grund ◽  
Mollie P Roediger ◽  
Gerald Friedland ◽  
Janet Darbyshire ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
The Impact

scholarly journals The impact of prescribed opioids on CD4 cell count recovery among HIV-infected patients newly initiating antiretroviral therapy

HIV Medicine ◽  
2016 ◽  
Vol 17 (10) ◽  
pp. 728-739 ◽  
Author(s):  
EJ Edelman ◽  
KS Gordon ◽  
JP Tate ◽  
WC Becker ◽  
K Bryant ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
The Impact ◽  
Count Recovery

scholarly journals The Impact of HIV Tropism on Decreases in CD4 Cell Count, Clinical Progression, and Subsequent Response to a First Antiretroviral Therapy Regimen

2008 ◽  
Vol 46 (10) ◽  
pp. 1617-1623 ◽  
Author(s):  
Laura Waters ◽  
Sundhiya Mandalia ◽  
Paul Randell ◽  
Adrian Wildfire ◽  
Brian Gazzard ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Clinical Progression ◽  
Cd4 Cell Count ◽  
Therapy Regimen ◽  
Subsequent Response ◽  
Cd4 Cell ◽  
The Impact

Failure to achieve a CD4+ cell count response on combination antiretroviral therapy despite consistent viral load suppression

AIDS ◽  
2014 ◽  
Vol 28 (6) ◽  
pp. 919-924 ◽  
Author(s):  
Jemma L. O’Connor ◽  
Colette J. Smith ◽  
Fiona C. Lampe ◽  
Teresa Hill ◽  
Mark Gompels ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Cell Count ◽  
Combination Antiretroviral Therapy ◽  
Viral Load Suppression ◽  
Cd4 Cell Count ◽  
Count Response ◽  
Cd4 Cell

scholarly journals Current CD4 Cell Count and the Short‐Term Risk of AIDS and Death before the Availability of Effective Antiretroviral Therapy in HIV‐Infected Children and Adults

2008 ◽  
Vol 197 (3) ◽  
pp. 398-404 ◽  
Author(s):  
David Dunn ◽  
Patrick Woodburn ◽  
Trinh Duong ◽  
Julian Peto ◽  
Andrew Phillips ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Short Term ◽  
Cd4 Cell Count ◽  
Cd4 Cell

scholarly journals Using record linkage to assess the impact of late presentation for care and treatment on short-term mortality among HIV-infected adults in rural South Africa.

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Chodziwadziwa Whiteson Kabudula ◽  
Georges Reniers ◽  
Francesc Xavier Gómez-Olivé ◽  
Kathleen Kahn ◽  
Stephen Tollman
Keyword(s):  
South Africa ◽  
Cell Count ◽  
Late Presentation ◽  
Short Term ◽  
Cd4 Cell Count ◽  
Short Term Mortality ◽  
Care And Treatment ◽  
Cd4 Cell ◽  
The Impact ◽  
Rural South Africa

ABSTRACT ObjectivesTo assess the impact of late presentation (CD4 cell count <200 cells/μl at presentation) for care and treatment on short-term mortality (death within a year of presentation) among HIV-infected adults in rural South Africa. ApproachWe applied deterministic and probabilistic record linkage approaches to link adult patients seeking care and treatment for HIV from a health facility between 2007 and 2013 to population under continuous surveillance by the Agincourt Health and Demographic Surveillance System (HDSS) in rural northeast South Africa. The resulting record-linked dataset was thereafter analysed to estimate short-term mortality (death within a year of presentation) differences in late presenters (initial presentation at health facility with CD4 cell count less than 200 cells/μl) and early presenters (presentation with CD4 cell count of 200 or more cells/μl). In the linked dataset, CD4 cell count was extracted from the health facility database where as date of death came from the HDSS database. ResultsA total of 3,553 patients who sought care and treatment for HIV at Bhubhezi clinic between 2007 and 2013 were linked to the Agincourt HDSS surveillance population. Proportion of patients classified as late presenters was 60.9%. Short-term mortality was 8.9% (317/3,553): 11.1% among those who presented late and 5.5 % among those who presented early (P<0.001). ConclusionRecord linkage facilitated the assessment of the impact of late presentation for care and treatment on short-term mortality among HIV-infected adults in rural South Africa. In the population studied, late presentation is high and is contributing to high mortality among people living with HIV. Strategies that would facilitate early presentation are needed in order to reduce mortality among people living with HIV.

scholarly journals Early Postseroconversion CD4 Cell Counts Independently Predict CD4 Cell Count Recovery in HIV-1–Postive Subjects Receiving Antiretroviral Therapy

2011 ◽  
Vol 57 (5) ◽  
pp. 387-395 ◽  
Author(s):  
Hemant Kulkarni ◽  
Jason F Okulicz ◽  
Greg Grandits ◽  
Nancy F Crum-Cianflone ◽  
Michael L Landrum ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Cell Counts ◽  
Cd4 Cell Counts ◽  
Cd4 Cell ◽  
Hiv 1 ◽  
Count Recovery
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