scholarly journals Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients

2019 ◽  
Vol 48 (5) ◽  
pp. 719-724 ◽  
Author(s):  
J Reiss ◽  
B Iglseder ◽  
R Alzner ◽  
B Mayr-Pirker ◽  
C Pirich ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Gait Speed ◽  
Older Patients ◽  
Handgrip Strength ◽  
Absolute Number ◽  
Case Finding ◽  
Newly Diagnosed ◽  
X Ray ◽  
Appendicular Muscle Mass ◽  
Geriatric Inpatients

Abstract Introduction we examined the consequences of applying the new EWGSOP2 algorithm for sarcopenia screening instead of the former EWGSOP algorithm (EWGSOP1) in geriatric inpatients. Methods the dataset of our formerly published Sarcopenia in Geriatric Elderly (SAGE) study includes 144 geriatric inpatients (86 women, 58 men, mean age 80.7±5.6 years) with measurements of gait speed, handgrip strength and appendicular muscle mass by dual x-ray absorptiometry (DXA). We analysed the agreement between EWGSOP and EWGSOP2 algorithms in identifying patients as sarcopenic/non-sarcopenic. Differences in the distribution sarcopenic vs. non-sarcopenic were assessed by Chi²-test. Results sarcopenia prevalence according to EWGSOP1 (41 (27.7%)) was significantly higher than with EWGSOP2 (26(18.1%), p<0.05). The sex-specific sarcopenia prevalence was 22.1% (EWGSOP1) and 17.4% (EWGSOP2), respectively, for women (difference not significant) and 37.9% vs. 19.4% for men (p<0.05%). The overall agreement in classifying subjects as sarcopenic/non-sarcopenic was 81.25% (81.4% for women, 81.0% for men). However, among the 41 sarcopenia cases identified by EWGSOP1, only 20 (48.8%) were diagnosed with sarcopenia by EWGSOP2 (9/19 w (47.4%), 11/22 m (50.0%)). Ten of 19 women (52.6%) and 11 of 22 men (50.0%) diagnosed with sarcopenia by EWGSOP1 were missed by EWGSOP2, while 6 of 15 women (40.0%) and 0 of 11 men (0.0%) were newly diagnosed. Discussion there is a substantial mismatch in sarcopenia case finding according to EWGSOP1 and EWGSOP2. The overall prevalence and the number of men diagnosed with sarcopenia are significantly lower in EWGSOP2. While the absolute number of women identified as sarcopenic remains relatively constant, the overlap of individual cases between the two definitions is low.

scholarly journals AB0267 BODY COMPOSITION IN PATIENTS WITH RHEUMATOID ARTHRITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1432.2-1432
Author(s):  
N. Toroptsova ◽  
O. Dobrovolskaya ◽  
N. Demin ◽  
L. Shornikova
Keyword(s):  
Rheumatoid Arthritis ◽  
Body Composition ◽  
Muscle Mass ◽  
Dual Energy ◽  
X Ray ◽  
T Score ◽  
Osteosarcopenic Obesity ◽  
The Mean ◽  
Total Fat ◽  
Appendicular Muscle Mass

Background:Rheumatoid arthritis (RA) is a complex inflammatory disease that modifies body composition. Using the dual-energy x-ray absorptiometry (DXA) in RA patients could be a method for body composition changes detection.Objectives:To study the body composition using DXA in patients with RA.Methods:The study involved 79 women with RA, median age 60 [55; 65] years. The bone mineral density (BMD) was measured by dual-energy x-ray absorptiometry using «Discovery A» (Hologic, USA). Assessment of body composition was carried out, using the program «Whole body». Sarcopenia (SP) was diagnosed as a decrease in appendicular mass index (AMI) <6.0 kg/m2. Osteoporosis (OP) was diagnosed as a decrease in T-score <-2.5 SD. Osteosarcopenia was determined when T-score was <-1.0 SD, AMI was <6.0 kg/m2, osteosarcopenic obesity - T-score was <-1.0 SD, AMI was <6.0 kg/m2and total fat was >35%.Results:The mean duration of RA was 9 [3; 11] years. The mean body mass index (BMI) was 27.6±4.8 kg/m2. Disease activity score in 28 joints-erythrocyte sedimentation rate was 4.5±1.3 points for the group. 39 (49.3%) patients used oral glucocorticoids continuously. Appendicular muscle mass and AMI were on average 17.8±3.0 kg and 6.8±1.0 kg/m2, respectively. AMI <6 kg/m2was detected in 20 (25.3%) patients. 56 (70.9%) women with RA had total fat > 35%, while only 22 (27.8%) of women with RA had obesity according to BMI (BMI >30 kg/m2). Isolated OP was found in 13 (16.5%), osteosarcopenia in 7 (8.9%) and osteosarcopenic obesity in 13 (16.5%) patients RA. No cases with isolated sarcopenia or sarcopenic obesity were detected. Only 3 (3.8%) patients did not have appendicular muscle mass, AMI and BMD decrease and overfat or obesity.Conclusion:About 97% women with RA had abnormal body composition phenotype: 16,5% - OP, 8.9% -osteosarcopenia, 16,5% - osteosarcopenic obesity and 54,4% - overfat.Disclosure of Interests:None declared

scholarly journals Lower Skeletal Muscle Mass at Admission Independently Predicts Falls and Mortality 3 Months Post-discharge in Hospitalized Older Patients

2018 ◽  
Vol 74 (10) ◽  
pp. 1650-1656 ◽  
Author(s):  
Esmee M Reijnierse ◽  
Sjors Verlaan ◽  
Vivien K Pham ◽  
Wen Kwang Lim ◽  
Carel G M Meskers ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Muscle Mass ◽  
Older Patients ◽  
Test Score ◽  
Handgrip Strength ◽  
Bed Rest ◽  
Post Discharge ◽  
Male Sex ◽  
Prospective Longitudinal

Abstract Background Approximately 10% of older adults are annually admitted to a hospital. Hospitalization is associated with a higher risk of falls and mortality after discharge. This study aimed to identify predictors at admission for falls and mortality 3 months post-discharge in hospitalized older patients. Methods The Evaluation of Muscle parameters in a Prospective cohort of Older patients at clinical Wards Exploring Relations with bed rest and malnutrition (EMPOWER) study is an observational, prospective longitudinal inception cohort of 378 patients aged 70 years and older who were subsequently admitted to a tertiary hospital (the Netherlands). Potential predictors for falls and mortality 3 months post-discharge were tested using univariate and multivariate logistic regression analyses and included the following domains: demographic (age, sex, living independently), lifestyle (alcohol, smoking), nutrition (SNAQ score), muscle mass (absolute, relative), physical function (handgrip strength, Katz ADL score), cognition (six-item cognitive impairment test score), and disease (medications, diseases). Results The mean age was 79.6 years (standard deviation 6.23) and 50% were male. Within 3 months post-discharge, 19% reported a fall and 13% deceased. Univariate predictors for falls were higher age, lower absolute muscle mass and higher six-item cognitive impairment test score. Lower absolute muscle mass independently predicted falls post-discharge (multivariate). Univariate predictors for mortality were higher age, male sex, no current alcohol use, higher SNAQ score, lower absolute and higher relative muscle mass, higher Katz ADL score and higher number of diseases. Male sex, higher SNAQ score, and lower absolute muscle mass independently predicted mortality post-discharge (multivariate). Conclusions In hospitalized older adults, muscle mass should be measured to predict future outcome. Future intervention studies should investigate if increasing muscle mass prevent short-term falls and mortality.

scholarly journals Prevalence of Sarcopenic Obesity Using Different Definitions and the Relationship With Strength and Physical Performance in the Canadian Longitudinal Study of Aging

2021 ◽  
Vol 11 ◽  
Author(s):  
Sarah A. Purcell ◽  
Michelle Mackenzie ◽  
Thiago G. Barbosa-Silva ◽  
Isabelle J. Dionne ◽  
Sunita Ghosh ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Physical Performance ◽  
Gait Speed ◽  
Walking Speed ◽  
Handgrip Strength ◽  
Sarcopenic Obesity ◽  
Cross Sectional ◽  
X Ray ◽  
The Relationship ◽  
Negative Health Outcomes

Sarcopenic obesity is associated with several negative health outcomes. However, the prevalence of this condition – and the relationship to physical performance parameters – varies across definitions. The aim of this cross-sectional investigation was to describe the prevalence of sarcopenic obesity using different published definitions and their relationship with handgrip strength and walking speed in older Canadian adults. Individuals aged 65+ in the Canadian Longitudinal Study on Aging (n = 11,803; 49.6% male, 50.4% female) were included. Body composition was measured using dual X-ray absorptiometry. Sarcopenic obesity was defined using 29 definitions. Low handgrip strength was identified as &lt; 27 kg in males and &lt; 16 kg in females and poor physical performance was defined as gait speed ≤ 0.8 m/s. The prevalence of sarcopenic obesity ranged from 0.1 to 85.3% in males, and from 0 to 80.4% in females. Sarcopenic obesity was frequently associated with low handgrip strength (p &lt; 0.05) in both males (14/17 definitions, 82.4%) and females (21/29 definitions, 72.4%). In very few definitions, sarcopenic obesity was associated with slow gait speed (males: 1/17 definitions [6.7%]; females: 2/29 [6.9%]). In conclusion, the prevalence of sarcopenic obesity varied greatly according to definitions and sarcopenic obesity was frequently associated with low handgrip strength.

SENSITIVITY AND SPECIFICITY OF THE HANDGRIP STRENGTH IN THE PREDICTION OF LOW MUSCLE MASS IN HOSPITALIZED OLDER PATIENTS

2012 ◽  
pp. 1-4
Author(s):  
V. Zanandrea ◽  
A.P. Rossi ◽  
M. Bertocchi ◽  
M. Zamboni
Keyword(s):  
Muscle Strength ◽  
Length Of Stay ◽  
Hospital Stay ◽  
Muscle Mass ◽  
Acute Care ◽  
Sensitivity And Specificity ◽  
Older Patients ◽  
Handgrip Strength ◽  
Hospitalized Patients ◽  
Acute Care Unit

To the Editor: In the article entitled “Potential prognosticvalue of handgrip strength in older hospitalized patients”published in the first issue of The Journal of Frailty & Aging(1), Savino and colleagues presented the handgrip strength as apredictor of hospitalization length of stay in older patientsadmitted to an acute care unit. Authors reported an inverseassociation between muscle strength at the admission andsubsequent duration of the hospital stay, even after adjustmentfor potential confounders.

scholarly journals Case finding for sarcopenia in geriatric inpatients: performance of bioimpedance analysis in comparison to dual X-ray absorptiometry

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Jens Reiss ◽  
Bernhard Iglseder ◽  
Martina Kreutzer ◽  
Ingrid Weilbuchner ◽  
Wolfgang Treschnitzer ◽  
...  
Keyword(s):  
Case Finding ◽  
Bioimpedance Analysis ◽  
X Ray ◽  
Geriatric Inpatients

scholarly journals Instrumented Assessment of Physical Activity Is Associated With Muscle Function but Not With Muscle Mass in a General Population

2017 ◽  
Vol 30 (9) ◽  
pp. 1462-1481 ◽  
Author(s):  
Anna G. M. Rojer ◽  
Esmee M. Reijnierse ◽  
Marijke C. Trappenburg ◽  
Rob C. van Lummel ◽  
Martijn Niessen ◽  
...  
Keyword(s):  
Physical Activity ◽  
General Population ◽  
Muscle Mass ◽  
Gait Speed ◽  
Muscle Function ◽  
Handgrip Strength ◽  
Group Discussion ◽  
Community Dwelling ◽  
Self Report ◽  
Middle Aged

Objectives: Self-reported physical activity has shown to affect muscle-related parameters. As self-report is likely biased, this study aimed to assess the association between instrumented assessment of physical activity (I-PA) and muscle-related parameters in a general population. Method: Included were 156 young-to-middle-aged and 80 older community-dwelling adults. Seven days of trunk accelerometry (DynaPort MoveMonitor, McRoberts B.V.) quantified daily physical activity (i.e., active/inactive duration, number and mean duration of active/inactive periods, and number of steps per day). Muscle-related parameters included muscle mass, handgrip strength, and gait speed. Results: I-PA was associated with handgrip strength in young-to-middle-aged adults and with gait speed in older adults. I-PA was not associated with muscle mass in either age group. Discussion: The association between I-PA and muscle-related parameters was age dependent. The lack of an association between I-PA and muscle mass indicates the relevance of muscle function rather than muscle mass.

scholarly journals Comparison of Sarcopenia Diagnostic Component Between Two Age Groups in Men

2020 ◽  
Vol 4 (6) ◽  
pp. 180-186
Author(s):  
Yahya Taqiuddin Robbani ◽  
Novira Widajanti ◽  
Nuniek Nugraheni Sulistiawaty
Keyword(s):  
Young Adult ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Gait Speed ◽  
Handgrip Strength ◽  
Age Groups ◽  
Sampling Technique ◽  
T Test ◽  
Bioelectric Impedance Analysis ◽  
Significant Difference

Sarcopenia is a condition which characterized by loss of muscle mass, muscle strength and muscle function due to aging. Some study found that sarcopenia prevalence was more common in men than women. This study aims to determine the comparison of sarcopenia diagnostic component between two group ages in men by observing and comparing muscle mass, handgrip strength and usual gait speed according to Asian Working Group on Sarcopenia (AWGS) diagnostic criteria that analyzed by Independent Sample T Test. The sample size with consecutive sampling technique was 149 mens which divided into two groups based on ages of elderly over 60 years (n = 73) and young adult between 18-40 years (n = 76). From the independent sample t test results, there was significant difference of muscle mass mean, handgrip strength mean and gait speed mean between elderly group and young adult group by 2.467 (SD ± 0.1454) kg/m2 (t(98.350) = -16.969; p = 0.000), 10.455 (SD ± 1.0983) kg (t(147) = -9.519; p = 0.000) and 0.4753 (SD ± 0.2808) m/s (t(11.636) = -16.747; p = 0.000) which means along with increasing age, sarcopenia diagnostic components value, i.e. muscle mass, muscle strength, and physical performance will also decrease. Keywords: sarcopenia; bioelectric impedance analysis; handgrip strength; gait speed; AWGS

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