scholarly journals Interaction of obstructive sleep apnoea and cognitive impairment with slow gait speed in middle-aged and older adults

2017 ◽  
Author(s):  
Sunghee Lee ◽  
Chol Shin
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Obstructive Sleep Apnoea ◽  
Gait Speed ◽  
Sleep Apnoea ◽  
Middle Aged ◽  
Obstructive Sleep

scholarly journals Detection of mild cognitive impairment in middle-aged and older adults with obstructive sleep apnoea

2018 ◽  
Vol 52 (5) ◽  
pp. 1801137 ◽  
Author(s):  
Katia Gagnon ◽  
Andrée-Ann Baril ◽  
Jacques Montplaisir ◽  
Julie Carrier ◽  
Sirin Chami ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Obstructive Sleep Apnoea ◽  
Mental State ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Sleep Apnoea ◽  
Screening Tests ◽  
Obstructive Sleep ◽  
State Examination

Obstructive sleep apnoea increases the risk for mild cognitive impairment and dementia. The present study aimed to characterise the ability of two cognitive screening tests, the Mini-Mental State Examination and the Montreal Cognitive Assessment, to detect mild cognitive impairment in adults aged 55–85 years with and without obstructive sleep apnoea.We included 42 subjects with mild and 67 subjects with moderate-to-severe obstructive sleep apnoea. We compared them to 22 control subjects. Mild cognitive impairment was diagnosed by a comprehensive neuropsychological assessment. We used receiver operating characteristic curves to assess the ability of the two screening tests to detect mild cognitive impairment.The two screening tests showed similar discriminative ability in control subjects. However, among the mild and the moderate-to-severe obstructive sleep apnoea groups, the Mini-Mental State Examination was not able to correctly identify subjects with mild cognitive impairment. The Montreal Cognitive Assessment's discriminant ability was acceptable in both sleep apnoea groups and was comparable to what was observed in controls.The Mini-Mental State Examination should not be used to screen for cognitive impairment in patients with obstructive sleep apnoea. The Montreal Cognitive Assessment could be used in clinical settings. However, clinicians should refer patients for neuropsychological assessment when neurodegenerative processes are suspected.

scholarly journals Structural brain correlates of obstructive sleep apnoea in older adults at risk for dementia

2018 ◽  
Vol 52 (1) ◽  
pp. 1800740 ◽  
Author(s):  
Nathan E. Cross ◽  
Negar Memarian ◽  
Shantel L. Duffy ◽  
Casey Paquola ◽  
Haley LaMonica ◽  
...  
Keyword(s):  
Older Adults ◽  
At Risk ◽  
Sleep Disturbance ◽  
Obstructive Sleep Apnoea ◽  
Cortical Thickness ◽  
Neuropsychological Testing ◽  
Sleep Apnoea ◽  
Oxygen Desaturation ◽  
Obstructive Sleep ◽  
Brain Correlates

This study aimed to investigate associations between obstructive sleep apnoea (OSA) and cortical thickness in older adults with subjective and objective cognitive difficulties, who are considered “at-risk” for dementia.83 middle-aged to older adults (51–88 years) underwent neuropsychological testing, polysomnography assessment of OSA and a structural magnetic resonance imaging brain scan. A principal components analysis was performed on OSA measures. Cortical thickness and subcortical volumes were compared to extracted components of “oxygen desaturation” and “sleep disturbance”.Oxygen desaturation was significantly related to reduced cortical thickness in the bilateral temporal lobes (left: r=−0.44, p<0.001; right: r=−0.39, p=0.003). Conversely, sleep disturbance was associated with increased thickness in the right postcentral gyrus (r=0.48, p<0.001), pericalcarine (r=0.50, p=0.005) and pars opercularis (r=0.46, p=0.009) and increased volume of the hippocampus and amygdala. Decreased thickness in the bilateral temporal regions was associated with reduced verbal encoding (r=0.28, p=0.010).Given the clinical significance of this sample in terms of dementia prevention, these changes in grey matter reveal how OSA might contribute to neurodegenerative processes in older adults.

scholarly journals A rare instance of retrosternal goitre presenting with obstructive sleep apnoea in a middle-aged person

2013 ◽  
Vol 4 (12) ◽  
pp. 1064-1066 ◽  
Author(s):  
Jude Rodrigues ◽  
Renny Furtado ◽  
Anant Ramani ◽  
Nivedita Mitta ◽  
Shantata Kudchadkar ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Middle Aged ◽  
Middle Aged Person ◽  
Aged Person ◽  
Obstructive Sleep ◽  
Rare Instance

Vitamin D levels in middle-aged patients with obstructive sleep apnoea syndrome

2017 ◽  
Vol 40 ◽  
pp. e104
Author(s):  
K. Archontogeorgis ◽  
E. Nena ◽  
A. Galanou ◽  
A. Zissimopoulos ◽  
D. Siopi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Obstructive Sleep Apnoea Syndrome ◽  
Middle Aged ◽  
Aged Patients ◽  
Sleep Apnoea Syndrome ◽  
Obstructive Sleep ◽  
Vitamin D Levels
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