Graves' Disease as an Immune Reconstitution Syndrome in an HIV-1–Positive Patient Commencing Effective Antiretroviral Therapy: Case Report and Literature Review

2006 ◽  
Vol 19 (1) ◽  
pp. 102-107 ◽  
Author(s):  
Brygida Knysz ◽  
Marek Bolanowski ◽  
Malgorzata Klimczak ◽  
Andrzej Gladysz ◽  
Katarzyna Zwolinska
Keyword(s):  
Case Report ◽  
Antiretroviral Therapy ◽  
Literature Review ◽  
Immune Reconstitution ◽  
Positive Patient ◽  
Graves Disease ◽  
Immune Reconstitution Syndrome ◽  
Hiv 1

scholarly journals Graves’ disease in HIV patient receiving antiretroviral therapy

2020 ◽  
Vol 66 (3) ◽  
pp. 22-26
Author(s):  
Tatyana B. Morgunova ◽  
Anastasia A. Zorina ◽  
Ekaterina S. Maloletkina ◽  
Yulia P. Sytch ◽  
Ariadna V. Vasileva ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Thyroid Hormones ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Clinical Case ◽  
Graves Disease ◽  
Thyroid Disorders ◽  
Immune Reconstitution Syndrome ◽  
Highly Active ◽  
The World

The article focuses on the clinical case of Graves disease in a patient with HIV infection who is receiving antiretroviral therapy. The number of HIV-infected patients has increased significantly in recent decades all over the world. The currently used highly active antiretroviral therapy can significantly improve the prognosis for these patients. However, its use is associated with a number of complications, in particular the development of immune reconstitution syndrome, under which the development of such autoimmune diseases as Graves disease, polymyositis and Guillain-Barre syndrome may occur. Therefore, we would like to draw the attention of doctors to the possibility of such a complication in patients receiving antiretroviral therapy. Timely diagnosis and treatment of thyroid disorders will help to avoid the complications associated with an excess or deficit of thyroid hormones.

scholarly journals Prostatic abscess as a presenting feature of paradoxical TB-IRIS

2014 ◽  
Vol 5 (4) ◽  
pp. 111-112
Author(s):  
Basavaprabhu Achappa ◽  
Archana Shenoy ◽  
Mak Ching Hsia ◽  
Sujani Yadlapati ◽  
Deepak Madi ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Clinical Suspicion ◽  
Positive Patient ◽  
Clinical Deterioration ◽  
Hiv Positive ◽  
Immune Reconstitution Syndrome ◽  
Medical Sciences ◽  
Rare Presentation ◽  
Prostatic Abscess

Paradoxical tuberculosis – immune reconstitution syndrome (pTB-IRIS) is a well-recognized cause of clinical deterioration in HIV tuberculosis (HIV-TB) co-infected individuals following initiation of antiretroviral therapy (ART). Here, we present a rare presentation of pTB-IRIS which manifested as a prostatic abscess in a case of HIV positive patient. To the best of our knowledge this is the first reported case of pTB-IRIS reported in literature which manifested as a prostatic abscess. Paradoxical TB-IRIS manifesting as prostatic abscess is extremely rare and a high index of clinical suspicion is needed to diagnose and appropriately treat it. DOI: http://dx.doi.org/10.3126/ajms.v5i4.9498 Asian Journal of Medical Sciences 2014 Vol.5(4); 111-112

HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review

2017 ◽  
Vol 24 (1) ◽  
pp. 123-127 ◽  
Author(s):  
Bruno F. Guedes ◽  
Márcio A. A. Vieira Filho ◽  
Clarice Listik ◽  
Rafael B. Carra ◽  
Cristiane B. Pereira ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Immune Reconstitution ◽  
Early Infection ◽  
Immune Reconstitution Syndrome ◽  
Ataxia Syndrome

scholarly journals Graves' Disease as a Manifestation of Immune Reconstitution in HIV-Infected Individuals after Initiation of Highly Active Antiretroviral Therapy

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Samad Rasul ◽  
Robert Delapenha ◽  
Faria Farhat ◽  
Jhansi Gajjala ◽  
Syeda Mehreen Zahra
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Immunological Response ◽  
Signs And Symptoms ◽  
Graves Disease ◽  
Typically Develop ◽  
Highly Active ◽  
Inflammatory Syndrome ◽  
Haart Therapy

Graves' disease after the initiation of highly active antiretroviral therapy (HAART) in certain HIV-1-infected individuals has been described as an immune reconstitution inflammatory syndrome (IRIS). This phenomenon should be suspected in individuals who present with clinical deterioration and a presentation suggestive of hyperthyroidism despite good virological and immunological response to HAART. Signs and symptoms of hyperthyroidism may be discrete or overt and typically develop 8–33 months after initiating therapy. One to two percent of HIV-infected patients can present with overt thyroid disease. Relatively few cases of Graves' IRIS have been reported in the literature to date. We describe four cases of Graves' IRIS in HIV-infected patients who were started on HAART therapy.

Sign in / Sign up

Export Citation Format

Share Document