scholarly journals Dobrava Virus Carried by the Yellow-Necked Field Mouse Apodemus flavicollis, Causing Hemorrhagic Fever with Renal Syndrome in Romania

2014 ◽  
Vol 14 (5) ◽  
pp. 358-364 ◽  
Author(s):  
Raluca Ioana Panculescu-Gatej ◽  
Anca Sirbu ◽  
Sorin Dinu ◽  
Maria Waldstrom ◽  
Paul Heyman ◽  
...  
Keyword(s):  
Hemorrhagic Fever ◽  
Field Mouse ◽  
Apodemus Flavicollis ◽  
Dobrava Virus

scholarly journals Dobrava virus: a mortal agent of hemorrhagic fever with renal syndrome

2013 ◽  
Vol 7 (10) ◽  
pp. 767-768
Author(s):  
Selçuk Kaya
Keyword(s):  
Full Text ◽  
Hemorrhagic Fever ◽  
Dobrava Virus

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Belgrade Virus, a Cause of Hemorrhagic Fever with Renal Syndrome in the Balkans, is Closely Related to Dobrava Virus of Field Mice

1993 ◽  
Vol 168 (3) ◽  
pp. 750-753 ◽  
Author(s):  
A. M. Taller ◽  
S.-Y. Xiao ◽  
M. S. Godec ◽  
A. Gligic ◽  
T. Avsic-Zupanc ◽  
...  
Keyword(s):  
Hemorrhagic Fever ◽  
The Balkans ◽  
Dobrava Virus ◽  
Field Mice

scholarly journals Isolation of Dobrava Virus from Apodemus flavicollis in Greece

2001 ◽  
Vol 39 (6) ◽  
pp. 2291-2293 ◽  
Author(s):  
A. Papa ◽  
K. Nemirov ◽  
H. Henttonen ◽  
J. Niemimaa ◽  
A. Antoniadis ◽  
...  
Keyword(s):  
Apodemus Flavicollis ◽  
Dobrava Virus

scholarly journals Dobrava Virus RNA Load in Patients Who Have Hemorrhagic Fever with Renal Syndrome

2008 ◽  
Vol 197 (5) ◽  
pp. 681-685 ◽  
Author(s):  
Ana Saksida ◽  
Darja Duh ◽  
Misa Korva ◽  
Tatjana Avsic‐Zupanc
Keyword(s):  
Hemorrhagic Fever ◽  
Dobrava Virus ◽  
Virus Rna

Diversity of nematodes in the yellow-necked field mouseApodemus flavicollisfrom the Peripannonic region of Serbia

2014 ◽  
Vol 90 (1) ◽  
pp. 14-20 ◽  
Author(s):  
B. Čabrilo ◽  
V.M. Jovanović ◽  
O. Bjelić-Čabrilo ◽  
I. Budinski ◽  
J. Blagojević ◽  
...  
Keyword(s):  
Species Richness ◽  
Generalized Linear Models ◽  
Linear Models ◽  
Alpha Diversity ◽  
Nematode Species ◽  
Diversity Indices ◽  
Taxonomic Distinctness ◽  
Field Mouse ◽  
Apodemus Flavicollis ◽  
Longitudinal Gradient

AbstractUp to six nematode species were identified from 86 specimens of the yellow-necked field mouseApodemus flavicollisfrom three mountainous localities known as Avala, Cer and Liškovac in Serbia. The highest prevalence of infection of 97% was recorded from Mt. Avala. Only one nematode species,Syphacia frederici, occurred in all three localities. There was complete overlap in nematode species from Mts. Avala and Liškovac, whereas the taxonomic distinctness of Mt. Cer was seen in the presence of the insect-transmitted speciesRictularia proni. Locality was a statistically significant factor in all the best-fitted generalized linear models of variation in abundances. The highest level of both species richness and parasite alpha diversity (Shannon'sH= 1.47) was found in the easternmost Mt. Liškovac, whereas the diversity indices were lowest for the westernmost Mt. Cer (Shannon'sH= 0.48). In view of this geographical difference, the beta diversity indices were calculated along a west to east longitudinal gradient.

scholarly journals Genetic Interaction between Distinct Dobrava Hantavirus Subtypes in Apodemus agrarius and A. flavicollis in Nature

2003 ◽  
Vol 77 (1) ◽  
pp. 804-809 ◽  
Author(s):  
Boris Klempa ◽  
Heiko A. Schmidt ◽  
Rainer Ulrich ◽  
Stefan Kaluz ◽  
Milan Labuda ◽  
...  
Keyword(s):  
Homologous Recombination ◽  
Genetic Interaction ◽  
Phylogenetic Analyses ◽  
Rodent Species ◽  
Apodemus Flavicollis ◽  
Genetic Lineages ◽  
Genetic Reassortment ◽  
Dobrava Virus ◽  
Molecular Phylogenetic ◽  
Evolutionary Trajectories

ABSTRACT Dobrava virus (DOBV) occurs in two different rodent species, Apodemus flavicollis (DOBV-Af) and A. agrarius (DOBV-Aa). We sequenced the S and M genomic segments from sympatric DOBV-Af and DOBV-Aa strains which fell into two distinct genetic lineages. Molecular phylogenetic analyses gave evidence for genetic reassortment between S and M segments of DOBV-Af and DOBV-Aa and indicated homologous recombination events in DOBV evolution. DOBV-Af and DOBV-Aa are distinct but also subject to genetic exchanges that affect their evolutionary trajectories.

scholarly journals HLA-Associated Hemorrhagic Fever with Renal Syndrome Disease Progression in Slovenian Patients

2011 ◽  
Vol 18 (9) ◽  
pp. 1435-1440 ◽  
Author(s):  
Miša Korva ◽  
Ana Saksida ◽  
Sabina Kunilo ◽  
Blanka Vidan Jeras ◽  
Tatjana Avšič-Županc
Keyword(s):  
Strong Association ◽  
Hemorrhagic Fever ◽  
Class Ii ◽  
Protective Role ◽  
Severe Form ◽  
Slovenian Population ◽  
Dobrava Virus ◽  
Histocompatibility Complex ◽  
Severity Of The Disease ◽  
Hla Molecules

ABSTRACTMajor histocompatibility complex (MHC) class I and class II genes regulate the balance between appropriate aggressive responses and invading pathogens while minimizing the destruction of host tissue. Several studies have shown that in hemorrhagic fever with renal syndrome (HFRS) patients, the disease outcome is determined by a complex interaction between the virus and immunopathologic and human genetic factors. In Slovenia, the severity of the disease caused by Puumala virus (PUUV) is significantly lower than that of HFRS due to Dobrava virus (DOBV). We have determined 23 different HLA-B and 12 different HLA-DRB1 types in Slovenian HFRS patients. Comparison of HLA frequencies between healthy individuals and HFRS patients showed no strong association with the susceptibility for hantaviral infection. Significant associations were recognized when the patient group was separated according to the virus responsible for the infection. DOBV-infected patients have a significantly higher frequency of HLA-B*35 than PUUV-infected patients. For HLA class II genes, the biggest difference between the PUUV- and DOBV-infected groups of patients was in HLA-DRB1*13, where this phenotype was more frequent in PUUV-infected patients, especially in the severe form of the disease. HLA-B*07 could play a protective role in PUUV-caused HFRS in the Slovenian population. Our study shows diverse associations of HLA molecules with DOBV- and PUUV-induced HFRS, and therefore, we presume that different hantaviruses are presented differently through the same HLA molecules and that this might lead to either a more severe or a milder form of the disease. In line with this idea, we have noticed that HLA-B*35 might be a genetic risk factor for DOBV infection in the Slovenian population.

scholarly journals Molecular Diagnostics of Hemorrhagic Fever with Renal Syndrome during a Dobrava Virus Infection Outbreak in the European Part of Russia

2009 ◽  
Vol 47 (12) ◽  
pp. 4029-4036 ◽  
Author(s):  
T. K. Dzagurova ◽  
B. Klempa ◽  
E. A. Tkachenko ◽  
G. P. Slyusareva ◽  
V. G. Morozov ◽  
...  
Keyword(s):  
Virus Infection ◽  
Molecular Diagnostics ◽  
Hemorrhagic Fever ◽  
European Part ◽  
Dobrava Virus ◽  
European Part Of Russia
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