Current Iodine Nutrition Status and Prevalence of Thyroid Disorders in Tibetan Adults in an Oxygen-Deficient Plateau, Tibet, China: A Population-Based Study

Thyroid ◽  
2020 ◽  
Vol 30 (5) ◽  
pp. 759-766 ◽  
Author(s):  
Peng Ning ◽  
Qian Ren ◽  
Di Teng ◽  
Zexin Zhang ◽  
Xuemei lv ◽  
...  
Keyword(s):  
Population Based ◽  
Nutrition Status ◽  
Thyroid Disorders ◽  
Iodine Nutrition ◽  
Population Based Study

Association between serum IGF-1 levels and thyroid disorders in a population-based study

2007 ◽  
Vol 115 (08) ◽  
Author(s):  
H Voelzke ◽  
N Friedrich ◽  
S Schipf ◽  
R Haring ◽  
J Luedemann ◽  
...  
Keyword(s):  
Population Based ◽  
Thyroid Disorders ◽  
Population Based Study

scholarly journals Changes in the Demographic and Clinicopathological Characteristics of Thyroid Cancer: A Population-Based Investigation in Algeria, 1993-2013

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Houda Boukheris ◽  
Arslan Bettayeb ◽  
Lesley Ann Anderson ◽  
Zineb Achour ◽  
Fatma Zohra Benbachir ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Case Series ◽  
Population Based ◽  
Clinicopathological Characteristics ◽  
Nutrition Status ◽  
Iodine Nutrition ◽  
Molecular Features ◽  
International Trends ◽  
Histologic Types ◽  
Over Time

Over the last three decades, the incidence of thyroid cancer has increased worldwide. The reasons for this increase remain controversial. In Algeria, however, to date, information on thyroid cancer has been limited to a hospital-based case series. We analyzed data from a population-based cohort study in Oran District, Algeria, to describe demographic and clinicopathological characteristics of patients diagnosed with thyroid cancer between 1993 and 2013. Medical records and pathology reports of thyroid cancer patients who had surgery were reviewed. Changes in demographic and clinicopathological features over the 21-year period are described. During the study period, thyroid cancer was diagnosed in 1248 women (86.5%, mean age 43.7±15.2 years) and 195 men (23.4%, mean age 48.1±15.9 years). Most cases (83.1% for women and 69.8% for men) sought a diagnosis following a self-neck check. The most common histologic types were papillary (58.3%), follicular (29.7%), anaplastic (4.1%), and medullary (0.8%) carcinomas. The incidence of papillary carcinomas significantly increased (p<0.001) while the incidence of other histologic types significantly decreased over time. Tumor size overall significantly decreased (p<0.001) while the frequency of small (≤20 mm) and larger (>20 mm) carcinomas significantly increased (p<0.05). The frequency of thyroid cancers with capsular effractions and angioinvasions also decreased over time. Thyroid cancer incidence in Algeria has increased substantially in line with international trends with changes in clinical practice being a possible contributing factor. However, the increasing papillary-to-follicular cancer ratio may be due to changes in iodine nutrition status in Algeria. Further research, including exploration of biological and molecular features of thyroid cancer, will enable a better understanding of risk factors and etiopathogenetic mechanisms.

More hypothyroidism and less hyperthyroidism with sufficient iodine nutrition compared to mild iodine deficiency—A comparative population-based study of older people

Maturitas ◽  
2009 ◽  
Vol 64 (2) ◽  
pp. 126-131 ◽  
Author(s):  
Stig Andersen ◽  
Finn Iversen ◽  
Steen Terpling ◽  
Klaus Michael Pedersen ◽  
Peter Gustenhoff ◽  
...  
Keyword(s):  
Older People ◽  
Iodine Deficiency ◽  
Population Based ◽  
Iodine Nutrition ◽  
Population Based Study ◽  
Comparative Population

scholarly journals High Prevalence of Thyroid Disorders in Pregnant Women in a Mildly Iodine-deficient Country: A Population-Based Study

2013 ◽  
Vol 98 (9) ◽  
pp. 3694-3701 ◽  
Author(s):  
Rodrigo Moreno-Reyes ◽  
Daniel Glinoer ◽  
Herman Van Oyen ◽  
Stefanie Vandevijvere
Keyword(s):  
Pregnant Women ◽  
Population Based ◽  
Thyroid Disorders ◽  
Population Based Study ◽  
High Prevalence

scholarly journals Reliability of thyroglobulin in serum compared with urinary iodine when assessing individual and population iodine nutrition status

2017 ◽  
Vol 117 (3) ◽  
pp. 441-449 ◽  
Author(s):  
Stig Andersen ◽  
Paneeraq Noahsen ◽  
Louise Westergaard ◽  
Peter Laurberg
Keyword(s):  
Subgroup Analysis ◽  
Urinary Iodine ◽  
Nutrition Status ◽  
Thyroid Disorders ◽  
Data Sampling ◽  
Iodine Nutrition ◽  
Serum Thyroglobulin ◽  
Thyroglobulin Antibodies ◽  
Supplement Use ◽  
Diet Supplement

AbstractThe occurrence of thyroid disorders relies on I nutrition and monitoring of all populations is recommended. Measuring I in urine is standard but thyroglobulin in serum is an alternative. This led us to assess the reliability of studies using serum thyroglobulin compared with urinary I to assess the I nutrition level and calculate the number of participants needed in a study with repeated data sampling in the same individuals for 1 year. Diet, supplement use and life style factors were assessed by questionnaires. We measured thyroglobulin and thyroglobulin antibodies in serum and I in urine. Participants were thirty-three Caucasians and sixty-four Inuit living in Greenland aged 30–49 years. Serum thyroglobulin decreased with rising I excretion (Kendall’sτ−0·29,P=0·005) and did not differ with ethnicity. Variation in individuals was lower for serum-thyroglobulin than for urinary I (mean individual CV: 15·1v. 46·1 %;P<0·01). It required 245 urine samples to be 95 % certain of having a urinary I excretion within 10 % of the true mean of the population. For serum-thyroglobulin the same precision required 206 samples. In an individual ten times more samples were needed to depict I deficiency when using urinary I excretion compared with serum-thyroglobulin. In conclusion, more participants are need to portray I deficiency in a population when using urinary I compared with serum-thyroglobulin, and about ten times more samples are needed in an individual. Adding serum-thyroglobulin to urinary I may inform surveys of I nutrition by allowing subgroup analysis with similar reliability.

scholarly journals Incidences of Hypothyroidism Associated With Surgical Procedures for Thyroid Disorders: A Nationwide Population-Based Study

2019 ◽  
Vol 10 ◽  
Author(s):  
Shin-Han Tsai ◽  
Shuo-Chen Chien ◽  
Phung-Anh Nguyen ◽  
Po-Han Chien ◽  
Hon-Ping Ma ◽  
...  
Keyword(s):  
Surgical Procedures ◽  
Population Based ◽  
Thyroid Disorders ◽  
Population Based Study

scholarly journals The Prevalence of Insufficient Iodine Intake in Pregnancy in Africa: a Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Charles Bitamazire Businge ◽  
Hannibal Tafadzwa Musarurwa ◽  
Benjamin Longo-Mbenza ◽  
Andre Pascal Kengne
Keyword(s):  
Iodine Deficiency ◽  
Meta Analysis ◽  
Grey Literature ◽  
Population Based ◽  
Iodine Intake ◽  
Nutrition Status ◽  
African Countries ◽  
Iodine Nutrition ◽  
Before And After ◽  
In Pregnancy

Abstract BackgroundFortification of foodstuffs with iodine, mainly through iodisation of salt, which commenced in several African countries after 1995 is the main method for mitigating iodine deficiency in Africa. We assessed the degree of iodine nutrition in pregnancy across Africa before and after the implementation of national iodine fortification programs (CRD42018099434).MethodsElectronic databases and grey literature were searched for baseline data before implementation of population-based iodine supplementation and for follow-up data up to September 2020. R-metamedian and metamean packages were used to pool country-specific median UIC estimates and derived mean UIC from studies with similar features. ResultsOf 54 African countries, 23 had data on iodine nutrition in pregnancy mostly from subnational samples. Data before 1995 showed that severe iodine deficiency was prevalent in pregnancy with a pooled pregnancy median UIC of 28.6 µg/L (95% CI 7.6 – 49.5). By 2005, five studies revealed a trend towards improvement in iodine nutrition state in pregnancy with a pooled pregnancy median UIC of 174.1 µg/L (95% CI 90.4 – 257.7). Between 2005 and 2020 increased numbers of national and subnational studies revealed that few African countries had sufficient, while most had mildly inadequate, and some severely inadequate iodine nutrition in pregnancy. The pooled pregnancy median UIC was 145 μg/L (95% CI 126 – 172). Conclusion Improvement in iodine nutrition status in pregnancy following the introduction of fortification of foodstuffs with iodine in Africa is sub-optimal, exposing a large proportion of pregnant women to the risk of iodine deficiency and associated disorders.

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