scholarly journals Common Genetic Variants in Sex Hormone Pathway Genes and Papillary Thyroid Cancer Risk

Thyroid ◽  
2012 ◽  
Vol 22 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Sara J. Schonfeld ◽  
Gila Neta ◽  
Erich M. Sturgis ◽  
Ruth M. Pfeiffer ◽  
Amy A. Hutchinson ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Papillary Thyroid Cancer ◽  
Genetic Variants ◽  
Sex Hormone ◽  
Papillary Thyroid ◽  
Common Genetic Variants ◽  
Thyroid Cancer Risk

scholarly journals Common Obesity-Related Genetic Variants and Papillary Thyroid Cancer Risk

2012 ◽  
Vol 21 (12) ◽  
pp. 2268-2271 ◽  
Author(s):  
Cari M. Kitahara ◽  
Gila Neta ◽  
Ruth M. Pfeiffer ◽  
Deukwoo Kwon ◽  
Li Xu ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Papillary Thyroid Cancer ◽  
Genetic Variants ◽  
Papillary Thyroid ◽  
Thyroid Cancer Risk

Serum osteopontin can improve papillary thyroid cancer risk assessment of Bethesda III thyroid nodules: a preliminary study

2021 ◽  
Author(s):  
Taha Ulutan Kars ◽  
Mustafa Kulaksizoglu ◽  
İbrahim Kılınç
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Papillary Thyroid Cancer ◽  
Thyroid Nodules ◽  
Cancer Risk Assessment ◽  
Papillary Thyroid ◽  
Operating Characteristics ◽  
Discriminative Performance ◽  
Thyroid Cancer Risk ◽  
Preliminary Study

Objective: Thyroid cancer can be detected in 5–10% of patients with thyroid nodules. Management may be a challenge if fine-needle aspiration biopsy yields Bethesda III findings. Most of these cases undergo surgery and are ultimately found benign. Our aim was to evaluate whether serum osteopontin can accurately estimate thyroid cancer risk in cases with cytologically Bethesda III thyroid nodules and, thereby, decrease the number of unnecessary surgical interventions. Design and Methods: We obtained blood samples of cases with repeated cytologically Bethesda III thyroid nodules before surgery, and followed up the pathology results after thyroidectomy. We evaluated serum osteopontin from 36 patients with papillary thyroid cancer and compared them with 40 benign cases. Results: Serum osteopontin levels in patients with papillary thyroid cancer are significantly higher than in benign cases (mean serum osteopontin: 10.48 ± 3.51 ng/mL vs 6.14 ± 2.29 ng/mL, p<0.001). The area under the receiver operating characteristics curve was 0.851, suggesting that serum osteopontin could have considerable discriminative performance. Conclusions: In our preliminary study, high serum osteopontin levels can predict the risk of papillary thyroid cancer in thyroid nodules with Bethesda III cytology. Further studies are necessary to confirm these findings.

Association of exposure to multiple metals with papillary thyroid cancer risk in China

2019 ◽  
Vol 26 (20) ◽  
pp. 20560-20572 ◽  
Author(s):  
Chi Zhang ◽  
Hua-Bing Wu ◽  
Meng-Xia Cheng ◽  
Ling Wang ◽  
Chao-Bing Gao ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Thyroid Cancer Risk

scholarly journals Common genetic variants related to genomic integrity and risk of papillary thyroid cancer

2011 ◽  
Vol 32 (8) ◽  
pp. 1231-1237 ◽  
Author(s):  
Gila Neta ◽  
Alina V. Brenner ◽  
Erich M. Sturgis ◽  
Ruth M. Pfeiffer ◽  
Amy A. Hutchinson ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Genetic Variants ◽  
Papillary Thyroid ◽  
Genomic Integrity ◽  
Common Genetic Variants

scholarly journals Common genetic variants in the 8q24 region and risk of papillary thyroid cancer

2012 ◽  
Vol 122 (5) ◽  
pp. 1040-1042 ◽  
Author(s):  
Gila Neta ◽  
Chu-Ling Yu ◽  
Alina Brenner ◽  
Fangyi Gu ◽  
Amy Hutchinson ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Genetic Variants ◽  
Papillary Thyroid ◽  
Common Genetic Variants ◽  
8Q24 Region
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