Multicompartmental Analysis of Triiodothyronine Kinetics in Hypothyroid Patients Treated Orally or Intravenously with Triiodothyronine

Thyroid ◽  
1994 ◽  
Vol 4 (3) ◽  
pp. 285-293 ◽  
Author(s):  
ANGEL A. ZANINOVICH ◽  
ELIAS EL TAMER ◽  
SARA EL TAMER ◽  
MARIA I. NOLI ◽  
MARGUERITE T. HAYS
Author(s):  
Dr. Jyoti Kumari ◽  
Dr. Dev Kant ◽  
Dr. Mala Mahto

Objectives: This present study was to compare the serum electrolytes (Na, K and Cl) imbalances in hypothyroidism, hyperthyroidism with euthyroidism female cases. Methods: A detail history, clinical examinations and relevant investigations were performed to all female thyroid cases. Thyroid hormones were estimated by chemiluminiscence method using Siemens Advia Centaur XP instrument. Electrolyte levels (Na+, k+ & Cl-) were measured by ion selective electrode method using Eschweiler combi. Results: Data was analyzed with the help of SPSS (version 26) software. Paired samples statistics was used. Mean ± standard deviation and t value were calculated. P value was taken less than or equal to 0.05 (p ≤ 0.05) for significant differences. Conclusions: This present study concluded that electrolytes sodium, potassium and chloride levels were significantly reduced in hypothyroidism female cases compared to euthyroids female (controls). This suggests that hypothyroid patients should be regularly checked for serum electrolytes. Early detection and treatment can prevent the further complications related to the disorder and will be helpful during the management of thyroid patients. Key words: Hypothyroidism, hyperthyroidism, euthyroidism, electrolytes.


1970 ◽  
Vol 64 (4) ◽  
pp. 630-636 ◽  
Author(s):  
Stephen C. Thorson ◽  
Ronald Tsujikawa ◽  
James L. Brown ◽  
Robert T. Morrison ◽  
Hamish W. McIntosh

ABSTRACT Serum thyroxine concentrations were determined in 66 euthyroid, 30 hyperthyroid and 13 hypothyroid patients using both the established Murphy method and a simplified method of competitive protein binding analysis. A diagnosis compatibility of 96% was found with both methods indicating that the simplified method has comparable clinical application as an initial screen of thyroid status.


2018 ◽  
Author(s):  
Nilgun Sesen Oncul ◽  
Mine Adas
Keyword(s):  

1980 ◽  
Vol 95 (4) ◽  
pp. 472-478 ◽  
Author(s):  
A. Eugene Pekary ◽  
Jerome M. Hershman ◽  
Clark T. Sawin

Abstract. Basal serum TSH and the peak TSH response to a 500 μg TRH bolus were measured in 57 euthyroid and in 29 hypothyroid subjects either receiving graded thyroid hormone replacement or acutely removed from full replacement therapy. Serum TSH, total T4 and T3 were determined by sensitive radioimmunoassay methods. The peak versus basal TSH data for hypothyroid patients were linear within individuals. The regression slope of the peak versus basal TSH data for all hypothyroid subjects did not differ significantly from the corresponding slope for all euthyroid subjects. Basal and peak TSH versus T3 and T4 data for hypothyroid patients were also linear within each individual. Moreover, the regression of the basal TSH values averaged over the non-replacement to full replacement state against the TSH versus T3 slope had a significant negative correlation. This trend leads to an array of regression lines which average to the familiar hyperbolic relationship between thyrotrophin and thyroid hormone levels in man.


2013 ◽  
Vol 17 (3) ◽  
pp. 460 ◽  
Author(s):  
AartiS Mahajan ◽  
Veena Chowdhury ◽  
DineshK Dhanwal ◽  
AjayK Jain ◽  
Ram Lal

1981 ◽  
Vol 27 (1) ◽  
pp. 149-152 ◽  
Author(s):  
M J Obregon ◽  
A Kurtz ◽  
R Ekins ◽  
G Morreale de Escobar

Abstract We assessed a commercial kit (Corning Medical) for "free" and total thyroxine determination, results being compared to those obtained by the Ekins and Ellis dialysis method (free thyroxine) and the method of Weeke and Orskov (total thyroxine). The kit procedure permits determination of both free and total thyroxine within 4 to 5 h, and the combined results may disclose changes in binding to plasma proteins that would be missed if only free thyroxine were determined. With both free-thyroxine methods, the values distinguished hyperthyroid patients from normal controls and pregnant women with 100% accuracy, but there was some overlap between hypothyroid patients and controls. Absolute values with the kit procedure often exceed those obtained by dialysis, especially for hypothyroid patients and pregnant women. We conclude that the kit may be of as much diagnostic value as the dialysis method if the limitations regarding absolute values are kept in mind and the test is not used as a substitute for thyrotropin determinations in cases of suspected hypothyroidism.


Thyroid ◽  
2018 ◽  
Vol 28 (6) ◽  
pp. 707-721 ◽  
Author(s):  
Sarah J. Peterson ◽  
Anne R. Cappola ◽  
M. Regina Castro ◽  
Colin M. Dayan ◽  
Alan P. Farwell ◽  
...  

1984 ◽  
Vol 66 (2) ◽  
pp. 18P-19P
Author(s):  
J Vora ◽  
D B Barnett ◽  
S Peterson ◽  
B P O'Malley ◽  
F D Rosenthal

2009 ◽  
Vol 62 (4) ◽  
pp. 446-451 ◽  
Author(s):  
Allan Carlé ◽  
Peter Laurberg ◽  
Inge Bülow Pedersen ◽  
Nils Knudsen ◽  
Hans Perrild ◽  
...  

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