Rabbit Calvarial Defect Model for Customized 3D-Printed Bone Grafts

2018 ◽  
Vol 24 (5) ◽  
pp. 255-262 ◽  
Author(s):  
Kang-Gon Lee ◽  
Kang-Sik Lee ◽  
Yu-Jeoung Kang ◽  
Jong-Hyun Hwang ◽  
Se-Hwan Lee ◽  
...  
2019 ◽  
Vol 7 (20) ◽  
pp. 3250-3259 ◽  
Author(s):  
Yali Miao ◽  
Yunhua Chen ◽  
Xiao Liu ◽  
Jingjing Diao ◽  
Naru Zhao ◽  
...  

3D-printed β-TCP scaffolds decorated with melatonin via dopamine mussel-inspired chemistry enhance the osteogenesis and in vivo bone regeneration.


2020 ◽  
Vol 20 ◽  
pp. 100706 ◽  
Author(s):  
Hoang Phuc Dang ◽  
Cedryck Vaquette ◽  
Tara Shabab ◽  
Román A. Pérez ◽  
Ying Yang ◽  
...  

2017 ◽  
Vol 13 (1) ◽  
pp. 015014 ◽  
Author(s):  
Jin-Hyung Shim ◽  
Jae-hyang Jeong ◽  
Joo-Yun Won ◽  
Ji-Hyeon Bae ◽  
Geunseon Ahn ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Xinchen Du ◽  
Le Wu ◽  
Hongyu Yan ◽  
Zhuyan Jiang ◽  
Shilin Li ◽  
...  

AbstractDeveloping an anti-infective shape-memory hemostatic sponge able to guide in situ tissue regeneration for noncompressible hemorrhages in civilian and battlefield settings remains a challenge. Here we engineer hemostatic chitosan sponges with highly interconnective microchannels by combining 3D printed microfiber leaching, freeze-drying, and superficial active modification. We demonstrate that the microchannelled alkylated chitosan sponge (MACS) exhibits the capacity for water and blood absorption, as well as rapid shape recovery. We show that compared to clinically used gauze, gelatin sponge, CELOX™, and CELOX™-gauze, the MACS provides higher pro-coagulant and hemostatic capacities in lethally normal and heparinized rat and pig liver perforation wound models. We demonstrate its anti-infective activity against S. aureus and E. coli and its promotion of liver parenchymal cell infiltration, vascularization, and tissue integration in a rat liver defect model. Overall, the MACS demonstrates promising clinical translational potential in treating lethal noncompressible hemorrhage and facilitating wound healing.


Drug Delivery ◽  
2019 ◽  
Vol 26 (1) ◽  
pp. 137-146 ◽  
Author(s):  
Xue Yang ◽  
Huthayfa N.S Almassri ◽  
Qiongyue Zhang ◽  
Yihui Ma ◽  
Dan Zhang ◽  
...  

2015 ◽  
Vol 103 (10) ◽  
pp. 3397-3406 ◽  
Author(s):  
Suzane C. Pigossi ◽  
Guilherme J. P. L. de Oliveira ◽  
Livia S. Finoti ◽  
Rafael Nepomuceno ◽  
Luis Carlos Spolidorio ◽  
...  

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