Endothelial Cells Assemble into a 3-Dimensional Prevascular Network in a Bone Tissue Engineering Construct

2006 ◽  
Vol 12 (9) ◽  
pp. 2685-2693 ◽  
Author(s):  
Jeroen Rouwkema ◽  
Jan De Boer ◽  
Clemens A. Van Blitterswijk
Keyword(s):  
Tissue Engineering ◽  
Endothelial Cells ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
3 Dimensional ◽  
Tissue Engineering Construct

Gelatin/Hydroxyapatite Scaffolds: Studies on Adhesion, Growth and Differentiation of Mesenchymal Stem Cells

2010 ◽  
Vol 93-94 ◽  
pp. 121-124
Author(s):  
Nuttapon Vachiraroj ◽  
Siriporn Damrongsakkul ◽  
Sorada Kanokpanont
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Calcium Content ◽  
Population Doubling ◽  
Population Doubling Time ◽  
3 Dimensional

In this work, we developed a 3-dimensional bone tissue engineering scaffold from type B gelatin and hydroxyapatite. Two types of scaffolds, pure gelatin (pI~5) (Gel) and gelatin/hydroxyapatite (30/70 wt./wt.) (Gel/HA), were prepared from concentrated solutions (5% wt./wt.) using foaming/freeze drying method. The results SEM revealed the interconnected-homogeneous pores of Gel and Gel/HA were 121  119 and 148  83m, respectively. Hydroxyapatite improved mechanical property of the gelatin scaffolds, especially at dry state. Compressive modulus of Gel and Gel/HA scaffolds were at 118±21.68 and 510±109.08 kPa, respectively. The results on in vitro cells culture showed that Gel/HA scaffolds promoted attachment of rat’s mesenchymal stem cells (MSC) to a 1.23 folds higher than the Gel scaffolds. Population doubling time (PDT) of MSC on Gel and Gel/HA scaffolds were 51.16 and 54.89 hours, respectively. In term of osteogenic differentiation, Gel/HA scaffolds tended to enhance ALP activity and calcium content of MSC better than those of the Gel scaffold. Therefore the Gel/HA scaffolds had a potential to be applied in bone tissue engineering.

scholarly journals Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering

Biomaterials ◽  
2007 ◽  
Vol 28 (2) ◽  
pp. 240-248 ◽  
Author(s):  
Marina I. Santos ◽  
Sabine Fuchs ◽  
Manuela E. Gomes ◽  
Ronald E. Unger ◽  
Rui L. Reis ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Endothelial Cells ◽  
Bone Tissue Engineering ◽  
Bone Tissue

3-Dimensional functionalized polycaprolactone-hyaluronic acid hydrogel constructs for bone tissue engineering

2017 ◽  
Vol 44 (4) ◽  
pp. 428-437 ◽  
Author(s):  
Stephen M. Hamlet ◽  
Cedryck Vaquette ◽  
Amit Shah ◽  
Dietmar W. Hutmacher ◽  
Saso Ivanovski
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
3 Dimensional ◽  
Hyaluronic Acid Hydrogel

Bone tissue engineering by primary osteoblast-like cells in a monolayer system and 3-dimensional collagen gel

2003 ◽  
Vol 61 (12) ◽  
pp. 1455-1462 ◽  
Author(s):  
Hans Peter Wiesmann ◽  
Noorul Nazer ◽  
Christina Klatt ◽  
Thomas Szuwart ◽  
Ulrich Meyer
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Collagen Gel ◽  
3 Dimensional ◽  
Primary Osteoblast

scholarly journals 3-dimensional composite scaffolds consisting of apatite-PLGA-atelocollagen for bone tissue engineering

2012 ◽  
Vol 31 (3) ◽  
pp. 465-471 ◽  
Author(s):  
Masaaki TAKECHI ◽  
Koji OHTA ◽  
Yoshiaki NINOMIYA ◽  
Misato TADA ◽  
Masayuki MINAMI ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffolds ◽  
3 Dimensional
Sign in / Sign up

Export Citation Format

Share Document