Electroacupuncture Alleviates Brain Damage Through Targeting of Neuronal Calcium Sensor 1 by miR-191a-5p After Ischemic Stroke

2017 ◽  
Vol 20 (6) ◽  
pp. 492-505 ◽  
Author(s):  
Heng Zhou ◽  
Cen Yang ◽  
Fuhai Bai ◽  
Zhi Ma ◽  
Jingyi Wang ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Brain Damage ◽  
Calcium Sensor ◽  
Neuronal Calcium Sensor

Ca2+-Myristoyl Switch in Neuronal Calcium Sensor-1: A Role of C-Terminal Segment

2015 ◽  
Vol 14 (4) ◽  
pp. 437-451 ◽  
Author(s):  
Viktoriia Baksheeva ◽  
Aliya Nazipova ◽  
Dmitry Zinchenko ◽  
Marina Serebryakova ◽  
Ivan Senin ◽  
...  
Keyword(s):  
Terminal Segment ◽  
Calcium Sensor ◽  
Neuronal Calcium Sensor ◽  
Myristoyl Switch

scholarly journals Development of a photochemical thrombosis investigation system to obtain a rabbit ischemic stroke model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoonhee Kim ◽  
Yoon Bum Lee ◽  
Seung Kuk Bae ◽  
Sung Suk Oh ◽  
Jong-ryul Choi
Keyword(s):  
Ischemic Stroke ◽  
Brain Damage ◽  
Rabbit Model ◽  
Specific Area ◽  
Brain Atlas ◽  
Rabbit Brain ◽  
Stroke Model ◽  
Triphenyltetrazolium Chloride ◽  
Induction System

AbstractPhotochemical thrombosis is a method for the induction of ischemic stroke in the cerebral cortex. It can generate localized ischemic infarcts in the desired region; therefore, it has been actively employed in establishing an ischemic stroke animal model and in vivo assays of diagnostic and therapeutic techniques for stroke. To establish a rabbit ischemic stroke model and overcome the shortcoming of previous studies that were difficult to build a standardized photothrombotic rabbit model, we developed a photochemical thrombosis induction system that can produce consistent brain damage on a specific area. To verify the generation of photothrombotic brain damage using the system, longitudinal magnetic resonance imaging, 2,3,5-triphenyltetrazolium chloride staining, and histological staining were applied. These analytical methods have a high correlation for ischemic infarction and are appropriate for analyzing photothrombotic brain damage in the rabbit brain. The results indicated that the photothrombosis induction system has a main advantage of being accurately controlled a targeted region of photothrombosis and can produce cerebral hemisphere lesions on the target region of the rabbit brain. In conjugation with brain atlas, it can induce photochemical ischemic stroke locally in the part of the brain that is responsible for a particular brain function and the system can be used to develop animal models with degraded specific functions. Also, the photochemical thrombosis induction system and a standardized rabbit ischemic stroke model that uses this system have the potential to be used for verifications of biomedical techniques for ischemic stroke at a preclinical stage in parallel with further performance improvements.

scholarly journals Differential effects of swimming training on neuronal calcium sensor-1 expression in rat hippocampus/cortex and in object recognition memory tasks

2012 ◽  
Vol 88 (4) ◽  
pp. 385-391 ◽  
Author(s):  
Luciana Estefani Drumond ◽  
Flávio Afonso Gonçalves Mourão ◽  
Hércules Ribeiro Leite ◽  
Renata Viana Abreu ◽  
Helton José Reis ◽  
...  
Keyword(s):  
Object Recognition ◽  
Recognition Memory ◽  
Rat Hippocampus ◽  
Calcium Sensor ◽  
Swimming Training ◽  
Differential Effects ◽  
Neuronal Calcium Sensor ◽  
Object Recognition Memory

scholarly journals Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection

Aging Cell ◽  
2013 ◽  
Vol 12 (5) ◽  
pp. 842-850 ◽  
Author(s):  
Hiramani Dhungana ◽  
Tarja Malm ◽  
Adam Denes ◽  
Piia Valonen ◽  
Sara Wojciechowski ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Brain Damage ◽  
Peripheral Infection

scholarly journals Early administration of MPC-n(IVIg) selectively accumulates in ischemic areas to protect inflammation-induced brain damage from ischemic stroke

Theranostics ◽  
2021 ◽  
Vol 11 (17) ◽  
pp. 8197-8217
Author(s):  
Weili Jin ◽  
Ye Wu ◽  
Ning Chen ◽  
Qixue Wang ◽  
Yunfei Wang ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Brain Damage ◽  
Early Administration
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