scholarly journals Transcranial Photobiomodulation for the Treatment of Major Depressive Disorder. The ELATED-2 Pilot Trial

2018 ◽  
Vol 36 (12) ◽  
pp. 634-646 ◽  
Author(s):  
Paolo Cassano ◽  
Samuel R. Petrie ◽  
David Mischoulon ◽  
Cristina Cusin ◽  
Husam Katnani ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Pilot Trial ◽  
Major Depressive

Trigeminal nerve stimulation in major depressive disorder: First proof of concept in an open pilot trial

2011 ◽  
Vol 22 (3) ◽  
pp. 475-478 ◽  
Author(s):  
Lara M. Schrader ◽  
Ian A. Cook ◽  
Patrick R. Miller ◽  
Eve R. Maremont ◽  
Christopher M. DeGiorgio
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Trigeminal Nerve ◽  
Nerve Stimulation ◽  
Pilot Trial ◽  
Proof Of Concept ◽  
Major Depressive ◽  
Trigeminal Nerve Stimulation ◽  
Open Pilot

Feasibility of an Exercise Program for Older Depressive Inpatients

GeroPsych ◽  
2015 ◽  
Vol 28 (4) ◽  
pp. 163-171 ◽  
Author(s):  
Andreas Heissel ◽  
Anou Vesterling ◽  
Stephanie A. White ◽  
Gunnar Kallies ◽  
Diana Behr ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Pilot Trial ◽  
Exercise Program ◽  
Exercise Group ◽  
Neurocognitive Functioning ◽  
Control Group ◽  
Active Control Group ◽  
Major Depressive ◽  
Older Inpatients ◽  
Relaxation Exercises

Abstract. Twelve older inpatients (M age = 66.8) with Major Depressive Disorder (MDD) participated in this controlled pilot trial either in a physical exercise group (PEG; n = 6; aerobic, strength, and coordination exercises) or an active control group (ACG; n = 6; relaxation exercises) twice a week for four weeks. While depressive symptoms decreased in both groups, reduction of symptoms was significantly larger in the PEG. However, the PEG had higher BDI scores compared to the ACG at pretest. Neurocognitive functioning and brain-derived neurotrophic factor (BDNF) concentration did not change significantly. A four-week exercise program may be a feasible adjunct therapy in older MDD patients but the efficacy of the program needs to be proven with larger samples.

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