Does the Use of Laser Photobiomodulation, Bone Morphogenetic Proteins, and Guided Bone Regeneration Improve the Outcome of Autologous Bone Grafts? An in Vivo Study in a Rodent Model

2008 ◽  
Vol 26 (4) ◽  
pp. 371-377 ◽  
Author(s):  
Cristian S. Torres ◽  
Jean N. dos Santos ◽  
Juliana S.C. Monteiro ◽  
Paulla G.M. Amorim ◽  
Antonio L.B. Pinheiro
2008 ◽  
Vol 26 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Antonio Luiz B. Pinheiro ◽  
Marleny E. Martinez Gerbi ◽  
Elizabeth Arruda Carneiro Ponzi ◽  
Luciana Maria Pedreira Ramalho ◽  
Aparecida M.C. Marques ◽  
...  

Author(s):  
Minh Khai Le Thieu ◽  
Håvard Jostein Haugen ◽  
Javier Sanz‐Esporrin ◽  
Mariano Sanz ◽  
Ståle Petter Lyngstadaas ◽  
...  

Materials ◽  
2016 ◽  
Vol 9 (11) ◽  
pp. 949 ◽  
Author(s):  
Eisner Salamanca ◽  
Chi-Yang Tsai ◽  
Yu-Hwa Pan ◽  
Yu-Te Lin ◽  
Haw-Ming Huang ◽  
...  

2018 ◽  
Vol 26 (0) ◽  
Author(s):  
Nicole Rosa de Freitas ◽  
Luísa Belluco Guerrini ◽  
Luis Augusto Esper ◽  
Michyele Cristhiane Sbrana ◽  
Gisele da Silva Dalben ◽  
...  

2008 ◽  
Vol 0 (0) ◽  
pp. 080316101137023-8
Author(s):  
Antonio Luiz B. Pinheiro ◽  
Marleny E. Martinez Gerbi ◽  
Elizabeth Arruda Carneiro Ponzi ◽  
Luciana Maria Pedreira Ramalho ◽  
Aparecida M.C. Marques ◽  
...  

2020 ◽  
Author(s):  
Yunzhi Peter Yang ◽  
Kevin Labus ◽  
Benjamin Gadomski ◽  
Arnaud Bruyas ◽  
Jeremiah Easley ◽  
...  

Abstract Autologous bone grafts are considered the gold standard grafting material for the treatment of nonunion, but in very large bone defects, traditional autograft alone is insufficient to induce repair. Recombinant human bone morphogenetic protein 2 (rhBMP-2) can stimulate bone regeneration and enhance the healing efficacy of bone grafts. The delivery of rhBMP-2 may even enable engineered synthetic scaffolds to be used in place of autologous bone grafts for the treatment of critical size defects, eliminating risks associated with autologous tissue harvest. We here demonstrate that an osteoinductive scaffold, fabricated by combining a 3D printed rigid polymer/ceramic composite scaffold with an rhBMP-2-eluting collagen sponge can treat extremely large-scale segmental defects in the sheep metatarsus. Bone regeneration after 24 weeks was evaluated by micro-computed tomography, mechanical testing, and histological characterization. Load-bearing cortical bridging was achieved in all animals, with increased bone volume observed in sheep that received osteoinductive scaffolds compared to sheep that received an rhBMP-2-eluting collagen sponge alone.


Polymers ◽  
2017 ◽  
Vol 9 (12) ◽  
pp. 410 ◽  
Author(s):  
Daniel Torres-Lagares ◽  
Lizett Castellanos-Cosano ◽  
María Serrera-Figallo ◽  
Francisco García-García ◽  
Carmen López-Santos ◽  
...  

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