scholarly journals Effects of Laser Therapy on Experimental Wound Healing Using Oxidized Regenerated Cellulose Hemostat

2008 ◽  
Vol 26 (1) ◽  
pp. 10-13 ◽  
Author(s):  
Lívia Prates Soares ◽  
Marília Gerhardt De Oliveira ◽  
Antônio Luiz Barbosa Pinheiro ◽  
Bruna Rodrigues Fronza ◽  
Marconi Eduardo Souza Maciel
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Regenerated Cellulose ◽  
Oxidized Regenerated Cellulose

scholarly journals Efficacy of Oxidized Regenerated Cellulose/Collagen Dressing for Management of Skin Wounds: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Li Zhang ◽  
Simei Wang ◽  
Meihua Tan ◽  
Hongwei Zhou ◽  
Ying Tang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Rate ◽  
Standard Of Care ◽  
Regenerated Cellulose ◽  
Relative Reduction ◽  
Skin Wounds ◽  
Oxidized Regenerated Cellulose ◽  
Significant Difference ◽  
Chronic Skin ◽  
Wound Healing Rate

Objective. The purpose of this study was to evaluate the wound healing efficacy of oxidized regenerated cellulose (ORC)/collagen dressing and ORC/collagen/silver-ORC dressings compared to standard of care or control in treatment of chronic skin wounds such as diabetic foot ulcers (DFUs), venous leg ulcers (VLUs), and pressure injuries sore ulcers (PISUs). Methods. An electronic search was carried out in four popular databases PubMed, Scopus, Embase, and CENTRAL to identify thirteen included studies, comparing the clinical efficacy of ORC/collagen dressings when compared to control in management of chronic skin wounds, especially DFUs, VLUs, and PISUs, and skin graft donor site wounds. Results. Consolidated data from thirteen comparative clinical studies undertaken for management of DFUs, VLUs, and PISUs showed favorable outcomes towards use of ORC/collagen compared to other traditional and hydrocolloid foam dressings in terms of wound healing rate ( P = 0.02 ) and percentage wound relative reduction ( P = 0.003 ). The time taken to achieve complete wound healing in the included studies did not show any statistical significant difference ( P = 0.24 ). There was no significant difference in adverse events between ORC/collagen-treated group and comparative group ( P = 0.19 ). Conclusion. ORC/collagen wound dressings are beneficial in terms of improved wound healing rate and percentage wound relative reduction compared to already existing traditional standard of care with non-MMP, inhibiting biomaterials such as moistened gauze, autologous growth factors, hydrocolloid foam dressings, or ovine extracellular matrix.

Hemostatic wound dressings: Predicting their effects by in vitro tests

2019 ◽  
Vol 33 (9) ◽  
pp. 1285-1297 ◽  
Author(s):  
Cornelia Wiegand ◽  
Martin Abel ◽  
Uta-Christina Hipler ◽  
Peter Elsner ◽  
Michael Zieger ◽  
...  
Keyword(s):  
Blood Clot ◽  
Wound Dressings ◽  
In Vitro Tests ◽  
Regenerated Cellulose ◽  
Oxidized Regenerated Cellulose ◽  
Inflammatory Reactions ◽  
In Vitro Techniques ◽  
Cotton Gauze

Background Application of controlled in vitro techniques can be used as a screening tool for the development of new hemostatic agents allowing quantitative assessment of overall hemostatic potential. Materials and methods Several tests were selected to evaluate the efficacy of cotton gauze, collagen, and oxidized regenerated cellulose for enhancing blood clotting, coagulation, and platelet activation. Results Visual inspection of dressings after blood contact proved the formation of blood clots. Scanning electron microscopy demonstrated the adsorption of blood cells and plasma proteins. Significantly enhanced blood clot formation was observed for collagen together with β-thromboglobulin increase and platelet count reduction. Oxidized regenerated cellulose demonstrated slower clotting rates not yielding any thrombin generation; yet, led to significantly increased thrombin-anti-thrombin-III complex levels compared to the other dressings. As hemostyptica ought to function without triggering any adverse events, induction of hemolysis, instigation of inflammatory reactions, and initiation of the innate complement system were also tested. Here, cotton gauze provoked high PMN elastase and elevated SC5b-9 concentrations. Conclusions A range of tests for desired and undesired effects of materials need to be combined to gain some degree of predictability of the in vivo situation. Collagen-based dressings demonstrated the highest hemostyptic properties with lowest adverse reactions whereas gauze did not induce high coagulation activation but rather activated leukocytes and complement.

Wound-healing effects of low-level laser therapy in diabetic rats involve the modulation of MMP-2 and MMP-9 and the redistribution of collagen types I and III

2013 ◽  
Vol 15 (4) ◽  
pp. 210-216 ◽  
Author(s):  
Andreia Aparecida Da Silva ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
Ana Carolina Araruna Alves ◽  
Caroline Sobral Rambo ◽  
Solange Almeida Dos Santos ◽  
...  
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Diabetic Rats ◽  
Low Level Laser Therapy ◽  
Collagen Types ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Treatment of a Bronchopleural Fistula With a Fogarty Catheter and Oxidized Regenerated Cellulose (Surgicel)

CHEST Journal ◽  
1994 ◽  
Vol 105 (6) ◽  
pp. 1879-1881 ◽  
Author(s):  
Juraj Sprung ◽  
Mark J. Krasna ◽  
Amy Yun ◽  
Padmini Thomas ◽  
Denis L. Bourke
Keyword(s):  
Bronchopleural Fistula ◽  
Regenerated Cellulose ◽  
Fogarty Catheter ◽  
Oxidized Regenerated Cellulose
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