scholarly journals Transplants of Neurotrophin-Producing Autologous Fibroblasts Promote Recovery of Treadmill Stepping in the Acute, Sub-Chronic, and Chronic Spinal Cat

2017 ◽  
Vol 34 (10) ◽  
pp. 1858-1872 ◽  
Author(s):  
Alexander J. Krupka ◽  
Itzhak Fischer ◽  
Michel A. Lemay
Keyword(s):  
Autologous Fibroblasts ◽  
Treadmill Stepping

TREADMILL STEPPING IN AN INFANT BORN PRETERM WITH A GRADE III INTRAVENTRICULAR HEMORRHAGE

1998 ◽  
Vol 10 (4) ◽  
pp. 170
Author(s):  
A W Bodkin ◽  
R S Baxter ◽  
C B Heriza ◽  
M J Rapport
Keyword(s):  
Intraventricular Hemorrhage ◽  
Treadmill Stepping ◽  
Grade Iii

scholarly journals BODY-WEIGHT SUPPORT TREADMILL STEPPING IN INFANTS WITH SPINA BIFIDA

2006 ◽  
Vol 18 (1) ◽  
pp. 104-105
Author(s):  
Beth A. Smith ◽  
Victoria A. Moerchen ◽  
Beverly D. Ulrich
Keyword(s):  
Body Weight ◽  
Spina Bifida ◽  
Body Weight Support ◽  
Weight Support ◽  
Treadmill Stepping

scholarly journals F-037HUMAN ACELLULAR DERMIS SEEDED WITH AUTOLOGOUS FIBROBLASTS ENHANCES BRONCHIAL ANASTOMOTIC HEALING IN AN IRRADIATED RODENT SLEEVE RESECTION MODEL

2013 ◽  
Vol 17 (suppl_1) ◽  
pp. S10-S10
Author(s):  
Eric Roessner ◽  
A. Schulmeister ◽  
M. Vitacolonna ◽  
C. Tsagogiorgas ◽  
M. Brockmann ◽  
...  
Keyword(s):  
Anastomotic Healing ◽  
Sleeve Resection ◽  
Acellular Dermis ◽  
Autologous Fibroblasts

scholarly journals Treatment of Cutaneous Ulcers with Multilayered Mixed Sheets of Autologous Fibroblasts and Peripheral Blood Mononuclear Cells

2018 ◽  
Vol 47 (1) ◽  
pp. 201-211 ◽  
Author(s):  
Takahiro Mizoguchi ◽  
Koji Ueno ◽  
Yuriko Takeuchi ◽  
Makoto Samura ◽  
Ryo Suzuki ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Healing Rate ◽  
Mononuclear Cells ◽  
Mixed Cell ◽  
Peripheral Blood Mononuclear ◽  
Fibroblast Migration ◽  
Autologous Fibroblasts ◽  
Blood Mononuclear Cells ◽  
Wound Healing Rate

Background/Aims: We have developed a mixed-cell sheet consisting of autologous fibroblasts and peripheral blood mononuclear cells with a high potency for angiogenesis and wound healing against refractory cutaneous ulcers in mouse and rabbit models. To increase the effectiveness of the mixed sheet, we developed a multilayered mixed sheet. Methods: We assessed the therapeutic effects of multilayered sheets on cutaneous ulcers in mice. Growth factors and chemokines were assessed by enzyme-linked immunosorbent assay. Angiogenesis and fibroblast migration were measured by using tube formation and migration assays. Wound healing rate of cutaneous ulcers was evaluated in mice with diabetes mellitus. Results: The concentration of secreted vascular endothelial growth factor, hepatocyte growth factor, transforming growth factor, C-X-C motif chemokine ligand (CXCL)-1, and CXCL-2 in multilayered sheets was much higher than that in single-layered mixed-cell sheets (single-layered sheets) and multilayered sheets of fibroblasts alone (fibroblast sheets). The supernatant in multilayered sheets enhanced angiogenic potency and fibroblast migration compared with single-layered and fibroblast sheets in an in vitro experiment. The wound healing rate in the multilayered sheet-treated group was higher compared with the no-treatment group (control) at the early stage of healing. Moreover, both vessel lumen area and microvessel density in tissues treated with multilayered sheets were significantly increased compared with tissues in the control group. Conclusion: Multilayered sheets promoted wound healing and microvascular angiogenesis in the skin by supplying growth factors and cytokines. Accordingly, our data suggest that multilayered sheets may be a promising therapeutic material for refractory cutaneous ulcers.

scholarly journals Autologous fibroblasts for the treatment of cutaneous loxoscelism: First experience

2019 ◽  
Vol 16 (6) ◽  
pp. 1503-1505
Author(s):  
Antonio Guglielmetti ◽  
Catalina Jahr ◽  
Matías Gompertz‐Mattar
Keyword(s):  
Autologous Fibroblasts

scholarly journals Two-stage implantation of the skin- and bone-integrated pylon seeded with autologous fibroblasts induced into osteoblast differentiation for direct skeletal attachment of limb prostheses

2013 ◽  
Vol 102 (9) ◽  
pp. 3033-3048 ◽  
Author(s):  
Maxim A. Shevtsov ◽  
Oleg V. Galibin ◽  
Nataliya M. Yudintceva ◽  
Miralda I. Blinova ◽  
George P. Pinaev ◽  
...  
Keyword(s):  
Osteoblast Differentiation ◽  
Two Stage ◽  
Autologous Fibroblasts

scholarly journals TRPM8-mediated cutaneous stimulation modulates motor neuron activity during treadmill stepping in mice

2019 ◽  
Vol 69 (6) ◽  
pp. 931-938 ◽  
Author(s):  
Kotaro Tamura ◽  
Satoshi Sugita ◽  
Tadayuki Tokunaga ◽  
Yoshihiko Minegishi ◽  
Noriyasu Ota
Keyword(s):  
Motor Neuron ◽  
Neuron Activity ◽  
Cutaneous Stimulation ◽  
Treadmill Stepping
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