Dietary Glycemic Index and Glycemic Load Are Associated with Metabolic Control in Type 2 Diabetes: The CAPRI Experience

2010 ◽  
Vol 8 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Katherine Esposito ◽  
Maria Ida Maiorino ◽  
Carmen Di Palo ◽  
Dario Giugliano
Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1280 ◽  
Author(s):  
Geoffrey Livesey ◽  
Richard Taylor ◽  
Helen F. Livesey ◽  
Anette E. Buyken ◽  
David J. A. Jenkins ◽  
...  

Published meta-analyses indicate significant but inconsistent incident type-2 diabetes (T2D)-dietary glycemic index (GI) and glycemic load (GL) risk ratios or risk relations (RR). It is now over a decade ago that a published meta-analysis used a predefined standard to identify valid studies. Considering valid studies only, and using random effects dose–response meta-analysis (DRM) while withdrawing spurious results (p < 0.05), we ascertained whether these relations would support nutrition guidance, specifically for an RR > 1.20 with a lower 95% confidence limit >1.10 across typical intakes (approximately 10th to 90th percentiles of population intakes). The combined T2D–GI RR was 1.27 (1.15–1.40) (p < 0.001, n = 10 studies) per 10 units GI, while that for the T2D–GL RR was 1.26 (1.15–1.37) (p < 0.001, n = 15) per 80 g/d GL in a 2000 kcal (8400 kJ) diet. The corresponding global DRM using restricted cubic splines were 1.87 (1.56–2.25) (p < 0.001, n = 10) and 1.89 (1.66–2.16) (p < 0.001, n = 15) from 47.6 to 76.1 units GI and 73 to 257 g/d GL in a 2000 kcal diet, respectively. In conclusion, among adults initially in good health, diets higher in GI or GL were robustly associated with incident T2D. Together with mechanistic and other data, this supports that consideration should be given to these dietary risk factors in nutrition advice. Concerning the public health relevance at the global level, our evidence indicates that GI and GL are substantial food markers predicting the development of T2D worldwide, for persons of European ancestry and of East Asian ancestry.


2008 ◽  
Vol 87 (1) ◽  
pp. 126-131 ◽  
Author(s):  
Nadine R Sahyoun ◽  
Amy L Anderson ◽  
Frances A Tylavsky ◽  
Jung Sun Lee ◽  
Deborah E Sellmeyer ◽  
...  

2012 ◽  
Vol 143 (1) ◽  
pp. 93-99 ◽  
Author(s):  
◽  
Ivonne Sluijs ◽  
Joline W. J. Beulens ◽  
Yvonne T. van der Schouw ◽  
Daphne L. van der A ◽  
...  

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Dallyla Jennifer Morais de Sousa ◽  
Larissa Layana Cardoso de Sousa ◽  
Joanne Ribeiro Rodrigues ◽  
Layla Rafaele Sampaio Learte ◽  
Gleyson Moura dos Santos

Introdução: Dietas com alto índice glicêmico (IG) induzem hiperglicemia o que induz ao estresse oxidativo e aumenta as citocinas pró-inflamatórias, incluindo IL-6 e TNF-α em indivíduos saudáveis e com tolerância a glicose diminuída. Objetivo: Realizar levantamento de dados na literatura sobre a influência do IG dos alimentos nas concentrações de marcadores inflamatórios. Material e método: Para a seleção dos estudos foi realizada uma busca de publicações indexadas nas bases de dados Pubmed, Scielo, Cochrane e Lilacs utilizando-se a combinação dos termos cadastrados no site DeCS (Descritores em Ciências da Saúde): Glycemic Index and Inflammation. Os artigos selecionados foram publicados no período compreendido entre 2008 e 2017, obtendo-se um total de 781 artigos, dos quais foram selecionados 38, após a remoção de duplicatas a amostra se constituiu por 10 artigos que foram lidos na integra. Resultados: Dentre os estudos obtidos, observou-se que 6 retratam a relação de dietas com alto IG e o  processo inflamatório, 2 relacionam o baixo IG com diminuição da inflamação e 2 por sua vez verificam tanto a relação da dieta de baixo IG como alto IG com o processo inflamatório. Conclusão: Foi demonstrado que uma dieta com alto IG aumenta as concentrações de marcadores inflamatórios como PCR, NF-kB e IL-6 e a dieta de baixo IG tem papel benéfico na inflamação crônica de baixo grau.Descritores: Inflamação; Índice Glicêmico; Dieta de Alto Índice Glicêmico.ReferênciasMayer LF, Bona KS, Abdalla FH, Almeida FL, Pozzobon RCR, Charão MF et al. Perspectivas laboratoriais na avaliação da resposta inflamatória. Rev Bras Farm. 2010;91(4):149-61.Lima RPE, Caetano CL, Nader DA Avaliação dos níveis séricos de proteína C-reativa em indivíduos com periodontite: um estudo piloto. Braz J Periodontol. 2016;6(1):13-9.Teixeira BC, Lopes AL, Macedo RCO, Correa CS, Ramis TR, Ribeiro JL et al. Marcadores inflamatórios, função endotelial e riscos cardiovasculares. J vasc bras. 2014;13(2):108-15.Cunha LS. Análise dos efeitos de dietas baseadas no índice glicêmico em diabéticos tipo 2 [monografia]. Brasília: Faculdade de Ciências da Educação e Saúde; 2013.Kim Y, Chen J, Wirth MD, Shivappa N, Herbert JR. Lower dietary inflammatory index scores are associated with lower glycemic index scores among college students. Nutrients. 2018;10(2):182.Dickinson S, Hancock DP, Petocz P, Ceriello A, Brand-Miller J. High-glycemic index carbohydrate increases nuclear factor-kappaB activation in mononuclear cells of young, lean healthy subjects. Am J Clin Nutr. 2008;87(5):1188-93.Du H, Van Der ADL, Van Bakel MIM, Van Der Kallen CJ, Blaak EE, Van Greevenbroek MM et al. Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population. Am J Clin Nutr. 2008;87(3):655-61.Levitan EB, Cook NR, Stampfer MJ, Ridker PM, Rexrode KM, Buring JE et al. Dietary glycemic index, dietary glycemic load, blood lipids, and C reactive protein. Metabolism. 2008;57(3):437-43.Buyken AE, Flood V, Empson M, Rochtchina E, Barclay AW, Brand-Miller J et al. Carbohydrate nutrition and inflammatory disease mortality in older adults. Am J Clin Nutr. 2010;92(3):634-43.Gogebakan O, Kohl A, Osterhoff MA, Van Baak MA, Jebb SA, Papadaki A et al. Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors. Circulation. 2011; 124(25):2829-38.Kelly KR, Haus JM, Solomon TP, Patrick-Melin AJ, Cook M, Rocco M et al. A low-glycemic index diet and exercise intervention reduces TNFa in isolated mononuclear cells of older, obese adults. J Nutr. 2011;141(6):1089-94.Bullo M, Casas R, Portillo MP, Basora J, Estruch R, Garcia-Arellano A et al. Dietary glycemic index/load and peripheral adipokines and inflammatory markers in elderly subjects at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2013;23(5):443-50.Goletzke J, Buyken AE, Joslowski G, Bolzenius K, Remer T, Carstensen M et al. Increased intake of carbohydrates from sources with a higher glycemic index and lower consumption of whole grains during puberty are prospectively associated with higher IL-6 concentrations in younger adulthood among healthy individuals. J Nutr. 2014;144(10):1586-93.Rouhani MH, Kelishadi R, Hashemipour M, Esmailzadeh A, Surkan PJ, Keshavarz A  et al. The impact of a low glycemic index diet on inflammatory markers and serum adiponectin concentration in adolescent overweight and obese girls: a randomized clinical trial. Horm Metab Res. 2016;48(4):251-56.Gomes JMG, Fabrini SP, Alfenas RCG. Low glycemic index diet reduces body fat and attenuates inflammatory and metabolic responses in patients with type 2 diabetes. Arch Endocrinol Metab. 2017;61(2):137-44.Mohanty P, Hamouda W, Garg R, Aljada A, Ghanim H, Dandona P. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J Clin Endocrinol Metab. 2000;85(8):2970-73.Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002;23(5):599-622.Ghanim H, Aljada A, Hofmeyer D, Syed T, Mohanty P, Dandona P. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation. 2004;110(12):1564-71.Hotamisligil GS. Inflammatory pathways and insulin action. Int J Obes Relat Metab Disord. 2003;27(Suppl 3):S53-5.Perseghin G, Petersen K, Shulman GI. Cellular mechanism of insulin resistance: potential links with inflammation. Int J Obes Relat Metab Disord. 2003;27(Suppl 3):S6-11.Bosma-den Boer MM, van Wetten ML, Pruimboom L. Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering. Nutr Metab (Lond). 2012;9(1):32.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 54-LB
Author(s):  
CRISTINA FACANHA ◽  
TATIANA U. PASSOS ◽  
LIVIANE C. MARANHÃO ◽  
FRANCIELLE C. COPPOLA ◽  
JULIANA D. MARTINS ◽  
...  

2011 ◽  
Vol 30 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Flávia M. Silva ◽  
Thais Steemburgo ◽  
Vanessa D.F. de Mello ◽  
Simone F. Tonding ◽  
Jorge L. Gross ◽  
...  

2014 ◽  
Vol 68 (4) ◽  
pp. 459-463 ◽  
Author(s):  
Maryam S Farvid ◽  
F Homayouni ◽  
M Shokoohi ◽  
A Fallah ◽  
Monir S Farvid

Food Research ◽  
2020 ◽  
Vol 4 (3) ◽  
pp. 722-730
Author(s):  
Nurul Hakimah ◽  
Mahmud Yunus ◽  
Sucipto Sucipto ◽  
Wignyanto Wignyanto ◽  
Aulanni'am Aulanni'am

This study was aimed to examine energy, density, proximate, dietary fiber and macronutrients ratio on the glycemic index and glycemic load of 6 kinds Indonesian local package menus made of red rice as a staple food and several other potentially antidiabetic food ingredients. The design was a quasi-experimental with 20 participants each of which were10 non-diabetic subjects (4 males and 6 females) aged between 20.3±1.0 years old and 10 subjects with type 2 diabetes (5 males and 5 females) aged between 54.4±9.3 years old. The results showed test package menu 1 (nasi liwet) has glycemic index and glycemic load can be accepted as healthy menu package in both, non-diabetic subjects (glycemic index = 23.8±9.2; glycemic load = 11.9±4.6) and diabetes subjects (glycemic index = 17.5±8.5; glycemic load = 8.7±3.3). There is a moderate to a strong negative correlation between glycemic index and the incremental area under the curve with the content of protein, fat, total dietary fiber, soluble dietary fiber, and moderate to strong positive correlation with macronutrients ratio. In conclusion, prevention of increased postprandial blood glucose in the management of type 2 diabetes mellitus diet can be done by preparing a local Indonesian menu package based on red rice food ingredients by considering the type of menu, protein, fat, total and soluble dietary fiber, and macronutrient ratio.


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