Acute Effect of the Transdermal Administration of Nicotine on Insulin Sensitivity in Healthy Individuals With and Without a Family History of Type 2 Diabetes Mellitus in the First Branch

2004 ◽  
Vol 2 (4) ◽  
pp. 227-233 ◽  
Author(s):  
José Miguel Mora-Martínez ◽  
Manuel González-Ortiz ◽  
Blanca R. Balcázar-Muñoz ◽  
Esperanza Martínez-Abundis
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Sensitivity ◽  
Family History ◽  
Acute Effect ◽  
Healthy Individuals ◽  
Transdermal Administration ◽  
History Of

scholarly journals Endocrinological and metabolic characteristics in patients who are non-obese and have polycystic ovary syndrome and different types of a family history of type 2 diabetes mellitus

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110166
Author(s):  
Yuan Wang ◽  
Hua Gao ◽  
Wen Di ◽  
Zhuowei Gu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
History Of ◽  
Second Degree

Objective We aimed to investigate whether patients with polycystic ovary syndrome (PCOS) and a family history (FH) of type 2 diabetes mellitus (T2DM) are at increased risk of endocrinological and metabolic abnormalities, and whether this risk differs between first-degree and second-degree relatives, and between maternal and paternal transmission. Methods A total of 680 patients with PCOS were enrolled in this retrospective, single-center study. Endocrine and glycolipid metabolism parameters were compared. Results The free androgen index (FAI), and levels of fasting blood glucose (FBG), fasting insulin (FINS), homeostatic model assessment-insulin resistance (HOMA-IR), total cholesterol (TC), and low-density lipoprotein cholesterol were significantly higher, whereas sex hormone binding globulin (SHBG) levels were significantly lower in patients with PCOS and a FH of T2DM. In patients with PCOS with a FH of T2DM in first-degree relatives, age and levels of FBG, FINS, and HOMA-IR were significantly higher than those who had a FH of T2DM in second-degree relatives. A maternal history of T2DM was associated with a higher body mass index, FAI, and TG levels, and lower SHBG levels. Conclusions Patients with PCOS and a FH of T2DM have more severe hyperandrogenism and metabolic disorders, especially in those with maternal transmission.

scholarly journals Metabolic dysfunction in women with bipolar disorder: the potential influence of family history of type 2 diabetes mellitus

2010 ◽  
Vol 12 (5) ◽  
pp. 504-513 ◽  
Author(s):  
Natalie L Rasgon ◽  
Heather A Kenna ◽  
Margaret F Reynolds-May ◽  
Pascale G Stemmle ◽  
Mytilee Vemuri ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Bipolar Disorder ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Metabolic Dysfunction ◽  
Potential Influence ◽  
History Of

scholarly journals Low Serum Adiponectin Levels in Korean Children with a Family History of Type 2 Diabetes Mellitus

2012 ◽  
Vol 77 (6) ◽  
pp. 382-387 ◽  
Author(s):  
Yeon Joung Oh ◽  
Hyo-Kyoung Nam ◽  
Young Jun Rhie ◽  
Sang Hee Park ◽  
Kee-Hyoung Lee
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Serum Adiponectin ◽  
Korean Children ◽  
History Of ◽  
Low Serum

Association of the TNF-α −308G/A polymorphism with family history of type 2 diabetes mellitus in a Mexican population

2012 ◽  
Vol 45 (1-2) ◽  
pp. 12-15 ◽  
Author(s):  
Elva Perez-Luque ◽  
Juan Manuel Malacara ◽  
Ma. Eugenia Garay-Sevilla ◽  
Martha Eugenia Fajardo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Mexican Population ◽  
Tnf Α ◽  
History Of

scholarly journals Coffee consumption and type 2 diabetes mellitus

Medicina ◽  
2009 ◽  
Vol 45 (1) ◽  
pp. 61
Author(s):  
Lina Radzevičienė ◽  
Rytas Ostrauskas
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Lower Risk ◽  
Conditional Logistic Regression ◽  
Coffee Consumption ◽  
Family History Of Diabetes ◽  
History Of

The aim of the study was to determine the association between coffee consumption and the risk of type 2 diabetes mellitus. Material and methods. A case-control study included 234 cases with newly confirmed diagnosis of type 2 diabetes mellitus and 468 controls who were free of the disease in 2001. Cases and controls were matched by gender and age (±5 years). Data on age, education level, occupation status, marital status, family history of diabetes, lifestyle (dietary habits, smoking habits, coffee consumption, alcohol consumption, physical activity), and stress were collected via a questionnaire. Variables were retained in models as confounders when their inclusion changed the value of the OR by more than 10% in any exposure category. Conditional logistic regression to compute the odds ratio (OR), 95% confidence interval (CI), and P for trend was used. Results. After adjustment for possible confounders (family history of diabetes, body mass index, eating speed, morning exercise, cigarette smoking, years of education, and stress), a statistically significant relationship was observed between type 2 diabetes mellitus and coffee consumption. Individuals consuming four or more cups of coffee per day were at lower risk of 2 diabetes mellitus (OR=0.51; 95% CI, 0.27–0.97) compared to those who consumed one or less than one cup of coffee per day. Conclusion. Habitual coffee consumption of four or more cups per day might be related to the lower risk of type 2 diabetes mellitus.

scholarly journals Factors Associated with Preventive Practices of Type 2 Diabetes Mellitus

2021 ◽  
Vol 9 (2) ◽  
pp. 151
Author(s):  
Nissa Kusariana ◽  
Tutut Okta Hardiyanti ◽  
Moh. Arie Wurjanto
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Family Support ◽  
Univariate Analysis ◽  
Knowledge Level ◽  
Preventive Practices ◽  
History Of

Background: Diabetes mellitus is a non-communicable disease that can be prevented by controlling the risk factors. Diabetes mellitus prevention practice is important so that prevention of type 2 diabetes mellitus can be carried out effectively. There are several factors that cause a person to practice prevention against diabetes mellitus. Objective: This study aims to analyze factors related to the practice of type 2 diabetes mellitus prevention among Diponegoro University students in Semarang. Methods: This is a quantitative study with an observational analytic approach and a cross-sectional study design. The time of research was May-August 2020. The instrument in this study was a google form questionnaire. The population in this study were active undergraduate students of Diponegoro University in 2020, amounting to 36,425 students. The sample size in this study was 407 respondents. The variables of the study were family history of type 2 diabetes mellitus, knowledge level, attitude, family support, and preventive practices of type 2 diabetes mellitus. This study used univariate analysis and bivariate analysis. The relationship test was performed using the chi-square test on a computer application. Results: This study showed there was a significant relationship between family history type 2 diabetes mellitus (0,017), knowledge level (0,00), attitude (0,00), and family support (0,00) for the preventive practices of type 2 diabetes mellitus in students. Conclusion: Family history of type 2 diabetes mellitus, knowledge level, attitude, and family support are factors related to the preventive practices of type 2 diabetes mellitus among students of Diponegoro University in Semarang. There is a need for education and provision of information related to knowledge on diabetes mellitus prevention for students at Diponegoro University, Semarang.

scholarly journals Life style factors associated with the risk of type 2 diabetes mellitus

2019 ◽  
Vol 1 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Bikash Shrestha ◽  
Bipin Nepal ◽  
Yagya Laxmi Shakya ◽  
Binaya Regmi
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Alcohol Use ◽  
Modifiable Risk Factors ◽  
Cross Sectional ◽  
History Of

 Introduction: Type 2 diabetes mellitus is the commonest form of diabetes affecting more than 90% of the diabetic population worldwide. The prevalence of type 2 diabetes and its complications are increasing in the world, including developing nations like Nepal. This study aimed to determine the association between the lifestyle risk factors and the risk of type 2 diabetes mellitus in Nepalese population. Methods: This is hospital based cross sectional observational study done in the urban area of Nepal. Records of clients coming for the general health checkup in Grande International Hospital were evaluated in this study. Comparisons of the lifestyle factors in participants having and not having type 2 diabetes mellitus were done. Results: Significant associations with diagnosis of diabetes mellitus (DM) type 2 were seen in age (P ≤ 0.001), associated hypertension (P ≤ 0.001), dyslipidemia, family history of DM (P ≤ 0.001), alcohol use (P ≤ 0.001), and tobacco use (P ≤ 0.001). Logistic regression analysis showed that the odds of having diabetes were high in age group above 40 (OR – 6.9, CI 3.82 – 12.47), history of hypertension (OR- 3.84, CI 2.42 – 6.08), tobacco users (OR-2.26, CI 1.12 – 4.53), alcohol users (OR-3.99, CI 2.47 – 6.44), family history of DM (OR-2.44, CI 1.53 – 3.89), and abdominal obesity in both males (OR-3.9, CI 2 – 7.4) and females (OR-9.6, CI 3.78 – 24.35). Conclusions: The modifiable risk factors - obesity, smoking and alcohol use carry significant risks of developing type 2 diabetes. These red flag signs call for urgent attention to look for and rectify the modifiable risk factors in Nepalese population to prevent diabetes.

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