scholarly journals Topical Ketamine with Other Adjuvants: Underutilized for Refractory Cancer Pain? A Case Series and Suggested Revision of the World Health Organization Stepladder for Cancer Pain

2020 ◽  
Vol 23 (9) ◽  
pp. 1167-1171 ◽  
Author(s):  
Jennifer A. Winegarden ◽  
Daniel B. Carr ◽  
Ylisabyth S. Bradshaw
Keyword(s):  
Cancer Pain ◽  
World Health Organization ◽  
Case Series ◽  
World Health ◽  
The World ◽  
Topical Ketamine ◽  
Health Organization

scholarly journals Covid-19 and Pregnancy: An Overview

2020 ◽  
Vol 42 (07) ◽  
pp. 420-426
Author(s):  
Pedro Castro ◽  
Ana Paula Matos ◽  
Heron Werner ◽  
Flávia Paiva Lopes ◽  
Gabriele Tonni ◽  
...  
Keyword(s):  
Public Health ◽  
Pregnant Women ◽  
World Health Organization ◽  
Case Series ◽  
Public Health Emergency ◽  
Present Review ◽  
World Health ◽  
The World ◽  
Coronavirus Infection ◽  
Health Organization

AbstractSince the World Health Organization (WHO) declared coronavirus infection (COVID-19) a Public Health Emergency of International Concern in January 2020, there have been many concerns about pregnant women and the possible effects of this emergency with catastrophic outcomes in many countries. Information on COVID-19 and pregnancy are scarce and spread throughout a few case series, with no more than 50 cases in total. The present review provides a brief analysis of COVID-19, pregnancy in the COVID-19 era, and the effects of COVID-19 on pregnancy.

scholarly journals Appearance of a novel measles G3 strain in multiple European countries within a two month period, 2010

2011 ◽  
Vol 16 (17) ◽  
Author(s):  
K E Brown ◽  
M N Mulders ◽  
F Freymuth ◽  
S Santibanez ◽  
M M Mosquera ◽  
...  
Keyword(s):  
East Asia ◽  
World Health Organization ◽  
Case Series ◽  
European Countries ◽  
World Health ◽  
South East Asia ◽  
Travel History ◽  
The World ◽  
Health Organization ◽  
Genotype G3

During late 2010, a previously unrecognised strain of measles genotype G3 virus was identified in five different European countries by the World Health Organization Measles and Rubella Laboratory Network. Apart from one, none had a travel history to south-east Asia, the usual source of G3 viruses, although epidemiological links could be established between some of the cases. This case series illustrates the value of genotyping and sequencing in tracking measles infections, and identifying otherwise unrecognised chains of transmission.

scholarly journals Coronavirus Disease and Abdominal Pain: Mechanism, Diagnostic, and Treatment

2021 ◽  
Vol 9 (F) ◽  
Author(s):  
Aleksandra Bozhinovska
Keyword(s):  
Abdominal Pain ◽  
World Health Organization ◽  
Case Reports ◽  
Case Series ◽  
World Health ◽  
Publication Date ◽  
Gi Symptoms ◽  
The World ◽  
Methods Of Synthesis ◽  
Health Organization

BACKGROUND: On March 11, 2020, the General Director of the World Health Organization has announced that according to the organization, the level of spread and severity of symptoms of coronavirus disease (COVID-19) is becoming alarming and because of that, it can be characterized as a pandemic. The assessment of the World Health Organization stimulated more urgent and belligerent actions from the governments as the number of case reports and studies on COVID-19 symptoms and treatment increased dramatically. AIM: In this paper, the aim is to make a review of the studies and case reports/series that indicate that abdominal pain is one of the manifestations of COVID-19. METHODS: A search was performed on two electronic databases: PubMed Central and Google Scholar, using the key words “COVID-19 and abdominal pain.” Case reports and case series in adults and children were included regardless of the language, region, or the publication date. The methods of synthesis and comparison were also used. RESULTS: In general, it can be noted that the manifestation of the COVID-19 infection on the digestive tract and the consequences on the same are not fully examined. CONCLUSION: The conclusion of the analyzed papers is that clinical practitioners in COVID-19 pandemic should carefully distinguish abdominal pain and other GI symptoms from COVID-19 manifestations and should exclude acute surgical condition.

High-dose or multi-day praziquantel for imported schistosomiasis? A systematic review

2019 ◽  
Vol 26 (7) ◽  
Author(s):  
Giulia Cucchetto ◽  
Dora Buonfrate ◽  
Valentina Marchese ◽  
Paola Rodari ◽  
Anna Ferrari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
World Health Organization ◽  
Case Reports ◽  
Case Series ◽  
Sub Saharan Africa ◽  
World Health ◽  
The World ◽  
Endemic Areas ◽  
Health Organization

Abstract Background Schistosomiasis affects more than 260 million people worldwide, mostly in sub-Saharan Africa, where more than 280 000 deaths per year are estimated. In the past few years, the increasing flow of migrants from endemic areas and the upward number of international travels have caused the emergence of the disease also in non-endemic areas. A single course of praziquantel (PZQ) 40 mg/kg is the first-line treatment recommended by the World Health Organization, mainly based on clinical trials conducted in endemic countries. No trials have been performed in non-endemic areas. Methods We carried out a systematic review of case reports and case series published between 1956 and August 2017 on cases of chronic schistosomiasis (infection acquired >3 months before) diagnosed in non-endemic areas and treated with PZQ. Primary outcome was to assess the number of different therapeutic regimens deployed and their frequency of use, calculated as the number of reports for each regimen over the total number of included cases. Results The final database included 99 case reports and 51 case series, for a total of 1433 patients. In 57 of the 150 records (38%) the administered treatment was different from the one recommended by the World Health Organization. The proportion of ‘alternative’ regimens included increased doses of PZQ (up to 80 mg/kg) and/or prolonged duration of treatment and/or doses repeated some days/weeks apart. About 50% of the records regarding Western short-term travellers reported a non-standard treatment. Conclusion This is the first complete catalogue of the published experience with PZQ outside of endemic areas in the situation where reinfection is not an issue. We found a wide heterogeneity of the therapeutic regimens reported. Multicenter clinical trials conducted in non-endemic areas and guidelines specifically addressing the treatment of imported cases of chronic schistosomiasis are needed.

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