scholarly journals Deep Brain Stimulation at End of Life: Clinical and Ethical Considerations

2020 ◽  
Vol 23 (4) ◽  
pp. 582-585
Author(s):  
Lauren R. Sankary ◽  
Paul J. Ford ◽  
Andre G. Machado ◽  
Laura J. Hoeksema ◽  
Renato V. Samala ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
End Of Life ◽  
Brain Stimulation ◽  
Ethical Considerations ◽  
Deep Brain

Ethical considerations in deep brain stimulation for psychiatric illness

2020 ◽  
pp. 247-251
Author(s):  
Ryan A. Grant ◽  
Casey H. Halpern ◽  
Gordon H. Baltuch ◽  
John P. O’Reardon ◽  
Arthur L. Caplan
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Psychiatric Illness ◽  
Ethical Considerations ◽  
Deep Brain

Pediatric Deep Brain Stimulation for Dystonia: Current State and Ethical Considerations

2020 ◽  
Vol 29 (4) ◽  
pp. 557-573
Author(s):  
KATRINA A. MUÑOZ ◽  
JENNIFER BLUMENTHAL-BARBY ◽  
ERIC A. STORCH ◽  
LAURA TORGERSON ◽  
GABRIEL LÁZARO-MUÑOZ
Keyword(s):  
Quality Of Life ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
The United States ◽  
Childhood Onset ◽  
Ethical Considerations ◽  
Current State ◽  
Limited Effectiveness ◽  
Deep Brain

AbstractDystonia is a movement disorder that can have a debilitating impact on motor functions and quality of life. There are 250,000 cases in the United States, most with childhood onset. Due to the limited effectiveness and side effects of available treatments, pediatric deep brain stimulation (pDBS) has emerged as an intervention for refractory dystonia. However, there is limited clinical and neuroethics research in this area of clinical practice. This paper examines whether it is ethically justified to offer pDBS to children with refractory dystonia. Given the favorable risk-benefit profile, it is concluded that offering pDBS is ethically justified for certain etiologies of dystonia, but it is less clear for others. In addition, various ethical and policy concerns are discussed, which need to be addressed to optimize the practice of offering pDBS for dystonia. Strategies are proposed to help address these concerns as pDBS continues to expand.

scholarly journals Researcher Perspectives on Ethical Considerations in Adaptive Deep Brain Stimulation Trials

2020 ◽  
Vol 14 ◽  
Author(s):  
Katrina A. Muñoz ◽  
Kristin Kostick ◽  
Clarissa Sanchez ◽  
Lavina Kalwani ◽  
Laura Torgerson ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ethical Considerations ◽  
Deep Brain

Deep brain stimulation in the management of disorders of consciousness: a review of physiology, previous reports, and ethical considerations

2010 ◽  
Vol 29 (2) ◽  
pp. E14 ◽  
Author(s):  
Anish N. Sen ◽  
Peter G. Campbell ◽  
Sanjay Yadla ◽  
Jack Jallo ◽  
Ashwini D. Sharan
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Daily Practice ◽  
Disorders Of Consciousness ◽  
Ethical Considerations ◽  
Physiological Mechanisms ◽  
Future Directions ◽  
Ethical Concerns ◽  
Minimally Conscious ◽  
Deep Brain

Patients suffering from disorders of consciousness constitute a population that exists largely outside of the daily practice patterns of neurosurgeons. Historically, treatment has focused on nursing and custodial issues with limited neurosurgical intervention. Recently, however, deep brain stimulation has been explored to restore cognitive and physical function to patients in minimally conscious states. In this article, the authors characterize the physiological mechanisms for the use of deep brain stimulation in persistently vegetative and minimally conscious patients, review published cases and associated ethical concerns, and discuss future directions of this technology.

scholarly journals Deep brain stimulation for obesity: rationale and approach to trial design

2015 ◽  
Vol 38 (6) ◽  
pp. E8 ◽  
Author(s):  
Allen L. Ho ◽  
Eric S. Sussman ◽  
Arjun V. Pendharkar ◽  
Dan E. Azagury ◽  
Cara Bohon ◽  
...  
Keyword(s):  
Morbid Obesity ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Trial Design ◽  
Maladaptive Behavior ◽  
Inclusion Criteria ◽  
Ethical Considerations ◽  
Reward Circuitry ◽  
The Us ◽  
Deep Brain

Obesity is one of the most serious public health concerns in the US. While bariatric surgery has been shown to be successful for treatment of morbid obesity for those who have undergone unsuccessful behavioral modification, its associated risks and rates of relapse are not insignificant. There exists a neurological basis for the binge-like feeding behavior observed in morbid obesity that is believed to be due to dysregulation of the reward circuitry. The authors present a review of the evidence of the neuroanatomical basis for obesity, the potential neural targets for deep brain stimulation (DBS), as well as a rationale for DBS and future trial design. Identification of an appropriate patient population that would most likely benefit from this type of therapy is essential. There are also significant cost and ethical considerations for such a neuromodulatory intervention designed to alter maladaptive behavior. Finally, the authors present a consolidated set of inclusion criteria and study end points that should serve as the basis for any trial of DBS for obesity.

Chapter 5 Ethical Considerations in the Use of Deep Brain Stimulation

2016 ◽  
pp. 85-98
Author(s):  
Alexander Fiksdal ◽  
Osama A. Abulseoud ◽  
Richard R. Sharp
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ethical Considerations ◽  
Deep Brain
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