scholarly journals Deep Brain Stimulation (DBS) and Spinal Cord Stimulation (SCS) – Ethical considerations in the use of Implants and Bio-Medical responsibility at manufacture

2018 ◽  
pp. 001-009
Author(s):  
Хан Аref
Keyword(s):  
Spinal Cord ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Ethical Considerations ◽  
Medical Responsibility ◽  
Deep Brain

scholarly journals Deep Brain Stimulation (DBS) and Spinal Cord Stimulation (SCS) – Ethical considerations in the use of Implants and Bio-Medical responsibility at manufacture

2018 ◽  
pp. 001-009
Author(s):  
Хан Аref
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Primary Objective ◽  
Implantable Devices ◽  
Ethical Considerations ◽  
Medical Responsibility ◽  
Deep Brain

Here in this brief we take a quick look into the use of certain biomedical devices and their benefits. At the same time, it is suggested that there are questionable practices by manufacturers, which raise concerns about corporate mores in general and around Ethics. As a Society, especially in these modern days, we need to be more aware of all that is going on and ensure accountability. Should not the primary objective be about saving lives and improving the quality of life, rather than putting the profit margin first. In this article we consider field of neuromodulation which is one of the fastest growing and the implantable devices such as pacemakers and IPGs. Let’s start off with a bit of background.

scholarly journals Ultrahigh Frequency Deep Brain Stimulation at 10 000 Hz Improves Motor Function

Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Irene E Harmsen ◽  
Darrin J Lee ◽  
Robert F Dallapiazza ◽  
Philippe De Vloo ◽  
Robert Chen ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Deep Brain Stimulation ◽  
Adverse Effects ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Ultrahigh Frequency ◽  
Clinical Effects ◽  
Stimulation Parameters ◽  
Clinical Benefits ◽  
Deep Brain

Abstract INTRODUCTION Stimulation frequency has been considered a crucial determinant of efficacy in deep brain stimulation (DBS). DBS at frequencies over 250 Hz is not currently employed and consensus in the field suggests that higher frequencies are not clinically effective. With the recent demonstration of clinically effective ultrahigh frequency (UHF) spinal cord stimulation at 10 kHz we tested whether UHF stimulation could also be clinically useful in movement disorder patients with DBS. We evaluated the clinical effects and safety of UHF DBS in patients with subthalamic nucleus (STN) or ventral intermediate thalamic nucleus (VIM) DBS. METHODS We studied the effects of conventional (130 Hz) and UHF stimulation in 5 patients with Parkinson's disease (PD) with STN DBS and in one patient with essential tremor (ET) with VIM DBS. We compared the clinical benefit and adverse effects of stimulation at various amplitudes either intraoperatively or postoperatively with the electrodes externalized. RESULTS Motor performance improved in all 6 patients with UHF DBS. About 10 kHz stimulation at amplitudes = 3.0 mA appeared to be as effective as 130 Hz in improving motor symptoms (46.2% vs 53.5% motor score reduction, P = .110, N = 90 trials). Interestingly, 10 kHz stimulation resulted in fewer stimulation-induced paresthesiae and speech adverse effects than 130 Hz stimulation. CONCLUSION Our results indicate that DBS at 10 kHz produces clinical benefits in patients with movement disorders. Like 10 kHz spinal cord stimulation, 10 kHz DBS has the potential to produce clinical benefits while possibly reducing stimulation-induced adverse effects. Further studies will be required to optimize UHF DBS stimulation parameters and to determine its clinical utility.

Spinal cord stimulation improves gait in patients with Parkinson's disease previously treated with deep brain stimulation

2016 ◽  
Vol 32 (2) ◽  
pp. 278-282 ◽  
Author(s):  
Carolina Pinto de Souza ◽  
Clement Hamani ◽  
Carolina Oliveira Souza ◽  
William Omar Lopez Contreras ◽  
Maria Gabriela dos Santos Ghilardi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Spinal Cord ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Previously Treated ◽  
Deep Brain

Deep Brain Stimulation and Spinal Cord Stimulation for Vegetative State and Minimally Conscious State

2013 ◽  
Vol 80 (3-4) ◽  
pp. S30.e1-S30.e9 ◽  
Author(s):  
Takamitsu Yamamoto ◽  
Yoichi Katayama ◽  
Toshiki Obuchi ◽  
Kazutaka Kobayashi ◽  
Hideki Oshima ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Vegetative State ◽  
Minimally Conscious State ◽  
Conscious State ◽  
Minimally Conscious ◽  
Deep Brain

Neuromodulation for Medically Refractory Neuropathic Pain: Spinal Cord Stimulation, Deep Brain Stimulation, Motor Cortex Stimulation, and Posterior Insula Stimulation

2021 ◽  
Vol 146 ◽  
pp. 246-260
Author(s):  
Giovanna Zambo Galafassi ◽  
Pedro Henrique Simm Pires de Aguiar ◽  
Renata Faria Simm ◽  
Paulo Roberto Franceschini ◽  
Marco Prist Filho ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Deep Brain Stimulation ◽  
Motor Cortex ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Motor Cortex Stimulation ◽  
Posterior Insula ◽  
Deep Brain

Primary orthostatic tremor: is deep brain stimulation better than spinal cord stimulation?

2017 ◽  
Vol 88 (9) ◽  
pp. 804-805 ◽  
Author(s):  
Han-Lin Chiang ◽  
Yi-Cheng Tai ◽  
Jacqueline McMaster ◽  
Victor SC Fung ◽  
Neil Mahant
Keyword(s):  
Spinal Cord ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Orthostatic Tremor ◽  
Better Than ◽  
Deep Brain

scholarly journals The continued relevance of Deep Brain Stimulation for chronic pain

2021 ◽  
Vol 6 (1) ◽  
pp. 009-014
Author(s):  
Farrell Sarah Marie ◽  
Aziz Tipu
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Spinal Cord Stimulation ◽  
Success Rates ◽  
Off Label ◽  
The Past ◽  
Variable Success ◽  
Deep Brain

For the millions of patients experiencing chronic pain despite pharmacotherapy, deep brain stimulation (DBS) provides a beacon of hope. Over the past decade the field has shifted away from DBS towards other forms of neuromodulation, particularly spinal cord stimulation (SCS). DBS for pain is still performed, albeit off-label in US and UK, and experiences variable success rates. SCS is an extremely useful tool for the modulation of pain but is limited in its application to specific pain aetiologies. We advocate use of DBS for pain, for patients for whom pharmacology has failed and for whom spinal cord stimulation is inadequate. DBS for chronic pain is at risk of premature neglect. Here we outline how this has come to pass, and in the process argue for the untapped potential for this procedure.

Ethical considerations in deep brain stimulation for psychiatric illness

2020 ◽  
pp. 247-251
Author(s):  
Ryan A. Grant ◽  
Casey H. Halpern ◽  
Gordon H. Baltuch ◽  
John P. O’Reardon ◽  
Arthur L. Caplan
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Psychiatric Illness ◽  
Ethical Considerations ◽  
Deep Brain
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