A Multicenter Cohort Study to Explore Differentiating Factors between Tumor Fever and Infection among Advanced Cancer Patients

2019 ◽  
Vol 22 (11) ◽  
pp. 1331-1336
Author(s):  
Takuya Odagiri ◽  
Tatsuya Morita ◽  
Hiroki Sakurai ◽  
Hirohide Yamada ◽  
Naoki Matsuo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Advanced Cancer Patients ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort

Prognostic awareness in advanced cancer patients and their caregivers: A longitudinal cohort study

2021 ◽  
Author(s):  
Martin Loučka ◽  
Karolína Vlčková ◽  
Anna Tučková ◽  
Kristýna Poláková ◽  
Adam Houska ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Longitudinal Cohort Study ◽  
Advanced Cancer Patients ◽  
Longitudinal Cohort

Long-Term Central Venous Catheter Infection in HIV-infected and Cancer Patients: A Multicenter Cohort Study

1999 ◽  
Vol 20 (7) ◽  
pp. 494-498 ◽  
Author(s):  
Pascal Astagneau ◽  
Sylvie Maugat ◽  
Tuan Tran-Minh ◽  
Marie-Cécile Douard ◽  
Pascale Longuet ◽  
...  
Keyword(s):  
Cohort Study ◽  
Central Venous Catheter ◽  
Cancer Patients ◽  
Venous Catheter ◽  
Central Venous ◽  
Hiv Patients ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Hiv And Cancer

Objectives:To evaluate and compare the risk of long-term central venous catheter (CVC) infection in human immunodeficiency virus (HIV)-infected and cancer patients.Design:Prospective multicenter cohort study based on active surveillance of long-term CVC manipulations and patient outcome over a 6-month period.Setting:Services of infectious diseases and oncology of 12 university hospitals in Paris, France.Participants:In 1995, all HIV and cancer patients with solid malignancy were included at the time of long-term CVC implantation.Results:Overall, 31.6% of long-term CVC infections were identified in 32% of 201 HIV and 5% of 255 cancer patients. Most were associated with bacteremia, most commonly coagulase-negative staphylococci. The long-term CVC time-related infection risk was greater in HIV than in cancer patients (3.78 vs 0.39 infections per 1,000 long-term CVC days; P<.001). The independent risk factors of long-term CVC infection were as follows: in HIV patients, frequency of long-term CVC handling and neutropenia; in cancer patients, poor Karnofsky performance status; in both HIV and cancer patients, recent history of bacterial infection. The risk of long-term CVC infection was similar for tunneled catheters and venous access ports in each population.Conclusions:Prevention of long-term CVC infection should focus first on better sterile precautions while handling long-term CVC, especially in HIV patients who have frequent and daily use of the long-term CVC.

scholarly journals Severe symptoms and very low quality-of-life among outpatients newly diagnosed with advanced cancer: data from a multicenter cohort study

2020 ◽  
Vol 28 (11) ◽  
pp. 5547-5555
Author(s):  
Waldemar Siemens ◽  
Stefan S. Schönsteiner ◽  
Claudia Lorena Orellana-Rios ◽  
Ulrike Schaekel ◽  
Jens Kessler ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Cohort Study ◽  
Advanced Cancer ◽  
Physical Symptoms ◽  
Newly Diagnosed ◽  
Multicenter Cohort Study ◽  
European Organization ◽  
Multicenter Cohort

Abstract Purpose The aim of this study was to identify symptoms of severe intensity or very low scores for quality of life (QoL) domains in newly diagnosed outpatients with advanced cancer. Methods This multicenter cohort study from a state-wide palliative care network included adult outpatients with advanced cancer diagnosed within the preceding 8 weeks from four comprehensive cancer centers (DRKS00006162, registered on 19 May 2014). We used the Palliative Outcome Scale (POS), Hospital Anxiety and Depression Scale, and European Organization for Research and Treatment of Cancer QoL Questionnaire-C30. For each questionnaire, cut-off scores defined symptoms and QoL domains that were considered “severe” or “very low.” Results Of 3155 patients screened, 481/592 (81.3%) were analyzed (mean age 62.4; women n = 245, 50.9%). We identified 324/481 (67.4%) patients experiencing at least one severe symptom or a very low QoL domain (median 2; range 0 to 16). Role functioning (n = 180, 37.4%), fatigue (n = 162, 33.7%), and social functioning (n = 126, 26.2%) were most commonly affected. QoL was very low in 89 patients (18.5%). Women experienced more anxiety symptoms, fatigue, and had lower POS scores. Patients often mentioned physical symptoms and fears of adverse events resulting from disease-modifying therapies (e.g., chemotherapy) as most relevant problems. Conclusions Already within the first 8 weeks after diagnosis, the majority of patients reported at least one severe symptom or a very low QoL domain. Gender differences were evident. The findings illustrate the value of early routine assessment of patient burden and the development of multi-professional and interdisciplinary palliative care.

scholarly journals Multicenter cohort study on the survival time of cancer patients dying at home or in a hospital: Does place matter?

Cancer ◽  
2016 ◽  
Vol 122 (9) ◽  
pp. 1453-1460 ◽  
Author(s):  
Jun Hamano ◽  
Takashi Yamaguchi ◽  
Isseki Maeda ◽  
Akihiko Suga ◽  
Takayuki Hisanaga ◽  
...  
Keyword(s):  
Cohort Study ◽  
Survival Time ◽  
Cancer Patients ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Dying At Home ◽  
At Home

Symptom clusters (SCs) in advanced cancer patients (ACPs): A prospective cohort study.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e20664-e20664
Author(s):  
Pedro Miguel Coecho Barata ◽  
Sonia Margarida Duarte De Oliveira ◽  
Filipa Santos ◽  
Frederico Filipe ◽  
Maria Paula Custódio ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Symptom Clusters ◽  
Advanced Cancer Patients
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